Results 41 to 50 of about 19,271 (221)
Interplay between bone and incretin hormones: A review [PDF]
, 2017 Bone is a tissue with multiple functions that is built from the molecular to anatomical levels to resist and adapt to mechanical strains. Among all the factors that might control the bone organization, a role for several gut hormones called "incretins ...
G. Mabilleau
core +4 more sources
Neuroprotective effects of glucose-dependent insulinotropic polypeptide in Alzheimer’s disease [PDF]
Reviews in the Neurosciences, 2016 AbstractGlucose-dependent insulinotropic polypeptide (GIP) is a member of the incretin hormones and growth factors. Neurons express the GIP receptor, and GIP and its agonists can pass through the blood brain barrier and show remarkable neuroprotective effects by protecting synapse function and numbers, promoting neuronal proliferation, reducing amyloid
Ji, Chenhui +4 more
openaire +3 more sources
Effects of Methotrexate on IL-6alphar, VCAM-1 and NF Kappa B Expression in a Rat Model of Metabolic Syndrome [PDF]
, 2016 Background: In this study, we used Methotrexate (Mtx) to examine the role of immunomodulation on the activation of IL-6 and VCAM-1, which could generate a microenvironment that supports cardiovascular remodelling.Methods: Male WKY and SHR rats were ...
Diez, Emiliano Raúl +4 more
core +1 more source
Glucose-dependent insulinotropic polypeptide - a new link in the development of obesity
Ожирение и метаболизм, 2015 Objective. Glucose-dependent insulinotropic polypeptide (GIP) as well as glucagon-like peptide-1 (GLP-1) is intestinal incretin hormone that stimulates insulin secretion in response to feeding. Much evidence of GIP contribution to obesity development has
Ekaterina Alekseevna Shestakova +3 more
doaj +1 more source
Bone Reports, 2021 Osteoblast lysyl oxidase (LOX) is a strongly up-regulated mRNA and protein by the glucose-dependent insulinotropic polypeptide (GIP). LOX is critically required for collagen maturation, and was shown to be dramatically down-regulated in a mouse model of ...
Eileen J. Daley, Philip C. Trackman
doaj +1 more source
The interplay of glucose-dependent insulinotropic polypeptide in adipose tissue. [PDF]
J EndocrinolAdipose tissue was once known as a reservoir for energy storage but is now considered a crucial organ for hormone and energy flux with important effects on health and disease. Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone secreted from the small intestinal K cells, responsible for augmenting insulin release, and has gained ...
Kagdi S, Lyons SA, Beaudry JL.
europepmc +3 more sources
A walnut-containing meal had similar effects on early satiety, CCK, and PYY, but attenuated the postprandial GLP-1 and insulin response compared to a nut-free control meal. [PDF]
, 2017 Regular nut consumption is associated with lower adiposity and reduced weight gain in adulthood. Walnut feeding studies have observed minimal effect on body weight despite potential additional energy intake.
Barkai, Hava-Shoshana +4 more
core +2 more sources
PLoS ONE, 2022 Pancreatic polypeptide (PP), secreted from γ cells of the islets of Langerhans, is a 36 amino-acid peptide encoded by the Ppy gene. Although previous studies have reported that PP causes a decrease in appetite, the molecular mechanism that regulates PP ...
Daisuke Saito +7 more
doaj +1 more source
Glucose-dependent insulinotropic polypeptide (GIP) directly affects collagen fibril diameter and collagen cross-linking in osteoblast cultures. [PDF]
, 2015 Glucose-dependent insulinotropic polypeptide (GIP) is absolutely crucial in order to obtain optimal bone strength and collagen quality. However, as the GIPR is expressed in several tissues other than bone, it is difficult to ascertain whether the ...
A. Mieczkowska +3 more
core +4 more sources
Nutrition Journal, 2019 Background Given the major role of glucose-dependent insulinotropic polypeptide (GIP) in the regulation of adiposity, this study examined the effects induced by a diet based on the Japanese tradition (SMART WASHOKU) on the visceral fat area (VFA) and GIP
Naoki Sakane +7 more
doaj +1 more source