Results 31 to 40 of about 4,211,438 (402)

Identification and Spatial Visualization of Dysregulated Bile Acid Metabolism in High-Fat Diet-Fed Mice by Mass Spectral Imaging

Frontiers in Nutrition, 2022
Changes in overall bile acid (BA) levels and specific BA metabolites are involved in metabolic diseases, gastrointestinal, and liver cancer. BAs have become established as important signaling molecules that enable fine-tuned inter-tissue communication ...
Qi Zhang, Qi Zhang, Zhen-Hua Wu, Zhen-Hua Wu, Zhen-Hua Wu, Shan-Shan Zhao, Shan-Shan Zhao, Shan-Shan Zhao, Jing Yang, Jing Yang, Jing Yang, Lei Chen, Lei Chen, Lei Chen, Xiao-Yu Wang, Xiao-Yu Wang, Xiao-Yu Wang, Zhan-You Wang, Hui-Xin Liu, Hui-Xin Liu, Hui-Xin Liu   +20 more
doaj   +1 more source

Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.

New England Journal of Medicine, 2008
BACKGROUND In patients with type 2 diabetes, the effects of intensive glucose control on vascular outcomes remain uncertain. METHODS We randomly assigned 11,140 patients with type 2 diabetes to undergo either standard glucose control or intensive ...
Anushka Patel, S. MacMahon, J. Chalmers, B. Neal, L. Billot, M. Woodward, M. Marre, M. Cooper, P. Glasziou, D. Grobbee, P. Hamet, S. Harrap, S. Heller, Li-sheng Liu, G. Mancia, C. Mogensen, C. Pan, N. Poulter, A. Rodgers, B. Williams, Severine Bompoint, B. D. de Galan, R. Joshi, F. Travert   +23 more
semanticscholar   +1 more source

Loss of AMP-activated protein kinase alpha 2 subunit in mouse beta-cells impairs glucose-stimulated insulin secretion and inhibits their sensitivity to hypoglycaemia [PDF]

, 2010
AMPK (AMP-activated protein kinase) signalling plays a key role in whole-body energy homoeostasis, although its precise role in pancreatic β-cell function remains unclear.
Affourtit, Ashcroft, Benoit Viollet, Bosi, Brand, Cantley, Chan, Chang, Choudhury, Claret, Cool, Craig Beall, David Carling, da Silva Xavier, Del Guerra, Dominic J. Withers, Fu, Gleason, Gloyn, Gloyn, Granot, Hind Al-Qassab, Johnson, Kaisa Piipari, Khan, Krauss, Leclerc, Lim, MacDonald, Marchetti, Mark A. Smith, Matschinsky, Meakin, Michael L. J. Ashford, Miki, Mirshamsi, Mukhtar, Nadeene Parker, Ning, Ostenson, Parton, Pi, Richards, Robertson, Salt, Seghers, Thorens, Vincent, Viollet, Viollet, Wajchenberg, Walker, Wang, Wang, Xue, Yamada, Zhang, Zhang, Zhang   +58 more
core   +6 more sources

The Role of Branched-Chain Amino Acids and Branched-Chain α-Keto Acid Dehydrogenase Kinase in Metabolic Disorders

Frontiers in Nutrition, 2022
Branched-chain amino acids (BCAAs), composed of leucine, isoleucine, and valine, are important essential amino acids in human physiology. Decades of studies have revealed their roles in protein synthesis, regulating neurotransmitter synthesis, and the ...
Chuang Du, Chuang Du, Chuang Du, Chuang Du, Wen-Jie Liu, Wen-Jie Liu, Wen-Jie Liu, Jing Yang, Jing Yang, Jing Yang, Shan-Shan Zhao, Shan-Shan Zhao, Shan-Shan Zhao, Shan-Shan Zhao, Hui-Xin Liu, Hui-Xin Liu, Hui-Xin Liu   +16 more
doaj   +1 more source

GLUT2, glucose sensing and glucose homeostasis [PDF]

Diabetologia, 2014
The glucose transporter isoform GLUT2 is expressed in liver, intestine, kidney and pancreatic islet beta cells, as well as in the central nervous system, in neurons, astrocytes and tanycytes. Physiological studies of genetically modified mice have revealed a role for GLUT2 in several regulatory mechanisms.
openaire   +4 more sources

Glucose control and vascular complications in veterans with type 2 diabetes.

New England Journal of Medicine, 2009
BACKGROUND The effects of intensive glucose control on cardiovascular events in patients with long-standing type 2 diabetes mellitus remain uncertain.
W. Duckworth, C. Abraira, Thomas E. Moritz, D. Reda, N. Emanuele, P. Reaven, F. Zieve, J. Marks, S. Davis, R. Hayward, S. Warren, S. Goldman, M. Mccarren, Mary Ellen Vitek, W. Henderson, Grant D. Huang   +15 more
semanticscholar   +1 more source

Glucose [PDF]

Scientific American, 1880
n ...
openaire   +2 more sources

The glycaemic effects of single doses of Panax ginseng in young healthy volunteers [PDF]

, 2006
The results of two acute placebo-controlled, double-blind cross-over studies assessing the effect of Panax ginseng (G115) on blood glucose levels are reported.
Kennedy, David, Reay, Jonathon, Scholey, Andrew   +2 more
core   +1 more source

International Consensus on Use of Continuous Glucose Monitoring

Diabetes Care, 2017
Measurement of glycated hemoglobin (HbA1c) has been the traditional method for assessing glycemic control. However, it does not reflect intra- and interday glycemic excursions that may lead to acute events (such as hypoglycemia) or postprandial ...
Danne T, Nimri R, Battelino T, Bergenstal Rm, Close Kl, D. Jh, G. S, Heinemann L, Hirsch I, Amiel Sa, Beck R, B. E, Buckingham B, Cobelli C, Dassau E, Doyle Fj, Heller S, Hovorka R, J. W, Jones T, Kordonouri O, Kovatchev B, Kowalski A, Laffel L, Maahs D, Murphy Hr, Nørgaard K, Parkin Cg, Renard E, Saboo B, Scharf M, Tamborlane Wv, Weinzimer Sa, Phillip M   +33 more
semanticscholar   +1 more source

Glucose [PDF]

Scientific American, 1886
n ...
openaire   +2 more sources