Possible involvement of nitric oxide and reactive oxygen species in glucose deprivation-induced activation of transcription factor rst2. [PDF]
PLoS ONE, 2013 Glucose is one of the most important sources of cellular nutrition and glucose deprivation induces various cellular responses. In Schizosaccharomyces pombe, zinc finger protein Rst2 is activated upon glucose deprivation, and regulates gene expression via
Toshiaki Kato, Xin Zhou, Yan Ma
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N-hydroxy-N'-(4-butyl-2-methylphenyl)-formamidine attenuates oxygen-glucose deprivation and reoxygenation-induced cerebral ischemia-reperfusion injury via regulation of microRNAs [PDF]
Journal of Integrative Neuroscience, 2020 Cerebral ischemia-reperfusion injury is a common complication that occurs during stroke treatment. Increasingly, microRNAs have been found to participate in the modulation of neuron function; however, the role of microRNAs in cerebral ischemia ...
Tiansong Yang, Dongyan Wang, Yuanyuan Qu, Yulin Wang, Yuenan Feng, Yan Yang, Qiang Luo, Xiaowei Sun, Guoqiang Yu, Jia He, Zhongren Sun, Yulan Zhu
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Repeated Glucose Deprivation/Reperfusion Induced PC-12 Cell Death through the Involvement of FOXO Transcription Factor [PDF]
Diabetes & Metabolism Journal, 2016 BackgroundCognitive impairment and brain damage in diabetes is suggested to be associated with hypoglycemia. The mechanisms of hypoglycemia-induced neural death and apoptosis are not clear and reperfusion injury may be involved.
Na Han +13 more
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ROS Mediate xCT-Dependent Cell Death in Human Breast Cancer Cells under Glucose Deprivation
Cells, 2020 xCT, also known as solute carrier family 7 member 11 (SLC7A11), the light chain of the cystine/glutamate antiporter, is positively correlated with cancer progression due to antioxidant function.
Mei-Chun Chen +5 more
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Astrocyte–neurone communication following oxygen–glucose deprivation [PDF]
Journal of Neurochemistry, 2005 AbstractWe looked at the possible interactions between astrocytes and neurones during reperfusion using an in vitro model of ischaemia–reperfusion injury, as a controlled environment that lends itself easily to manipulation of the numerous variables involved in such an insult.
S, Griffin, J B, Clark, L, Canevari
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Cancer control via glucose and glutamine deprivation [PDF]
Journal of Internal Medicine, 2013 Dear Sir, Polet and Feron [1] elucidate inter alia pharmacological interventions, which affect the glucose, glutamine and lactate pathways. These are important due to their putative anticancer effects. Recapitulating their therapeutic effect is unfortunately difficult by only cytotoxic means [2] due to, among others, the ‘innocent bystander effect’ [3].
E H, Mathews, L, Liebenberg
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Study of global transcriptional changes of N-GlcNAc2 proteins-producing T24 bladder carcinoma cells under glucose deprivation. [PDF]
PLoS ONE, 2013 Increased levels of N-linked (β-N- acetylglucosamine)2 [N-GlcNAc2]-modified proteins have been recognized to be an effective response to glucose deprivation.
Takahiro Isono +3 more
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GRASP55 facilitates autophagosome maturation under glucose deprivation [PDF]
Molecular & Cellular Oncology, 2018 Under growth condition, the Golgi reassembly-stacking protein of 55 kDa (GRASP55)/GORASP2 serves as the "glue" to hold adjacent Golgi cisternae into stacks by forming trans-oligomers. Upon glucose starvation, GRASP55 is de-O-GlcNAcylated and functions as a membrane tether to facilitate autophagosome-lysosome fusion through the interactions with LC3-II ...
Xiaoyan Zhang, Yanzhuang Wang
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Critical role of H2O2 generated by NOX4 during cellular response under glucose deprivation. [PDF]
PLoS ONE, 2013 Glucose is the most efficient energy source, and various cancer cells depend on glycolysis for energy production. For maintenance of survival and proliferation, glucose sensing and adaptation to poor nutritional circumstances must be well organized in ...
Satoshi Owada +3 more
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EXPRESSION OF UBIQUITIN SPECIFIC PEPTIDASE GENES IN IRE1 KNOCKDOWN U87 GLIOMA CELLS UPON GLUCOSE DEPRIVATION [PDF]
Biotechnologia Acta, 2016 We have studied the effect of glucose deprivation on the expression of genes encoding for ubiquitin specific peptidases — USP and autophagy related 7 ATG7 in U87 glioma cells in relation to inhibition of inositol requiring enzyme-1 (IRE1).
O. H. Minchenko +5 more
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