Flurbiprofen ameliorates glucose deprivation-induced leptin resistance [PDF]
Leptin resistance is one of the mechanisms involved in the pathophysiology of obesity. The present study showed that glucose deprivation inhibited leptin-induced phosphorylation of signal transducer and activator of transcription 3 (STAT3) and signal ...
Toru Hosoi +3 more
doaj +2 more sources
GLUT1 protects prostate cancer cells from glucose deprivation-induced oxidative stress [PDF]
Glucose, chief metabolic support for cancer cell survival and growth, is mainly imported into cells by facilitated glucose transporters (GLUTs). The increase in glucose uptake along with tumor progression is due to an increment of facilitative glucose ...
Pedro Gonzalez-Menendez +9 more
doaj +2 more sources
Study of global transcriptional changes of N-GlcNAc2 proteins-producing T24 bladder carcinoma cells under glucose deprivation. [PDF]
Increased levels of N-linked (β-N- acetylglucosamine)2 [N-GlcNAc2]-modified proteins have been recognized to be an effective response to glucose deprivation.
Takahiro Isono +3 more
doaj +1 more source
Critical role of H2O2 generated by NOX4 during cellular response under glucose deprivation. [PDF]
Glucose is the most efficient energy source, and various cancer cells depend on glycolysis for energy production. For maintenance of survival and proliferation, glucose sensing and adaptation to poor nutritional circumstances must be well organized in ...
Satoshi Owada +3 more
doaj +1 more source
EXPRESSION OF UBIQUITIN SPECIFIC PEPTIDASE GENES IN IRE1 KNOCKDOWN U87 GLIOMA CELLS UPON GLUCOSE DEPRIVATION [PDF]
We have studied the effect of glucose deprivation on the expression of genes encoding for ubiquitin specific peptidases — USP and autophagy related 7 ATG7 in U87 glioma cells in relation to inhibition of inositol requiring enzyme-1 (IRE1).
O. H. Minchenko +5 more
doaj +1 more source
GLUCOSE DEPRIVATION AFFECTS THE EXPRESSION OF LONP1 AND CATHEPSINS IN IRE1 KNOCKDOWN U87 GLIOMA CELLS [PDF]
To study the effect of glucose deprivation on the expression of genes encoding for LONP1/PRSS15 and cathepsins in U87 glioma cells in relation to inhibition of inositol requiring enzyme-1 (IRE1) was the aim of the research.
O. H. Minchenko +5 more
doaj +1 more source
ERN1 dependent regulation of TMED10, MYL9, SPOCK1, CUL4A and CUL4B genes expression at glucose and glutamine deprivations in U87 glioma cells [PDF]
It was shown previously that inhibition of ERN1 (endoplasmic reticulum to nucleus signaling 1) pathway, a central mediator of the unfolded protein response, leads to suppression of tumor growth through down-regulation of key pro-proliferative and up ...
O. H. Minchenko +7 more
doaj +1 more source
Effects of daytime food intake on memory consolidation during sleep or sleep deprivation. [PDF]
Sleep enhances memory consolidation. Bearing in mind that food intake produces many metabolic signals that can influence memory processing in humans (e.g., insulin), the present study addressed the question as to whether the enhancing effect of sleep on ...
Fujita, Naoko +21 more
core +2 more sources
Exercise modifies lipid and glucose metabolism alterations induced by sleep deprivation in mice
Insufficient sleep compromises lipid/glucose homeostasis. In opposition, exercise increases energy expenditure and has positive effects on glucose and fatty acid metabolism.
Paulo Iury Gomes Nunes +9 more
core +1 more source
The role of biological rhythms and blood glucose levels in maintaining a positive mood state. [PDF]
A thesis submitted in partial fulfilment of the requirements of the University of Wolverhampton for the degree of Doctor of PhilosophyAlthough the effects of both the menstrual and circadian cycles on mood have been well documented, the question of ...
Martino, Orsolina I.
core +3 more sources

