The Effect of IDO on Neural Progenitor Cell Survival Under Oxygen Glucose Deprivation
Frontiers in Cellular Neuroscience, 2020 Objective: Indoleamine 2,3-dioxygenase (IDO) activity plays an important role in many neurological disorders in the central nervous system, which may be associated with immunomodulation or anti-inflammatory activity.
Jixian Wang +6 more
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IRE1 KNOCKDOWN MODIFIES GLUCOSE AND GLUTAMINE DEPRIVATION EFFECTS ON THE EXPRESSION OF PROLIFERATION RELATED GENES IN U87 GLIOMA CELLS [PDF]
Biotechnologia Acta, 2016 We have studied the expression of genes encoding proliferation related factors and enzymes such as IL13RA2, KRT18, CD24, ING1, ING2, MYL9, BET1, TRAPPC3, ENDOG, POLG, TSFM, and MTIF2 in U87 glioma cells upon glucose and glutamine deprivation in relation ...
D. O. Tsymbal +4 more
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Inhibition of IRE1 modifies effect of glucose deprivation on the expression of TNFα-related genes in U87 glioma cells [PDF]
The Ukrainian Biochemical Journal, 2015 Inhibition of IRE1 (inositol requiring enzyme-1), the major signaling pathway of endoplasmic reticulum stress, significantly decreases glioma cell proliferation and tumor growth.
I. V. Kryvdiuk +5 more
doaj +1 more source
Neurobiology of Disease, 2012 The use of energy substrates, such as lactate and pyruvate, has been shown to improve synaptic function when administered during glucose deprivation. In the present study, we investigated whether prolonged incubation with monocarboxylate (pyruvate or ...
Pavan K. Shetty +3 more
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Moderate glucose deprivation preconditions myocardium against infarction [PDF]
, 2005 Glucose-free perfusion preconditions myocardium against the consequences of subsequent ischemia. We investigated whether mitochondrial ATP-sensitive potassium (mK (ATP)) channels are involved in preconditioning by glucose deprivation, and whether ...
D. Ebel +9 more
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Phospholipase D1 mediates AMP-activated protein kinase signaling for glucose uptake. [PDF]
PLoS ONE, 2010 Glucose homeostasis is maintained by a balance between hepatic glucose production and peripheral glucose utilization. In skeletal muscle cells, glucose utilization is primarily regulated by glucose uptake.
Jong Hyun Kim +5 more
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IRE1 KNOCKDOWN MODIFIES THE GLUTAMINE AND GLUCOSE DEPRIVATION EFFECT ON THE EXPRESSION OF NUCLEAR GENES ENCODING MITOCHONDRIAL PROTEINS IN U87 GLIOMA CELLS [PDF]
Biotechnologia Acta, 2016 We have studied the glucose and glutamine deprivation effect on the expression of nuclear genes encoding mitochondrial proteins in U87 glioma cells in relation to inhibition of inositol requiring enzyme-1 (IRE1).
O. O. , D. O. , D. O. , O.O. , O. H.
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Exosome Release by Glucose Deprivation Is Important for the Viability of TSC-Null Cells
Cells, 2022 The control of exosome release is associated with numerous physiological and pathological activities, and that release is often indicative of health, disease, and environmental nutrient stress.
Ji-Hyun Bae, Jong Hyun Kim
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Tumor-suppressive function of EZH2 is through inhibiting glutaminase
Cell Death and Disease, 2021 Tumors can use metabolic reprogramming to survive nutrient stress. Epigenetic regulators play a critical role in metabolic adaptation. Here we screened a sgRNA library to identify epigenetic regulators responsible for the vulnerability of colorectal ...
Yongfeng Liu +10 more
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Ischemia-Like Stress Conditions Stimulate Trophic Activities of Adipose-Derived Stromal/Stem Cells
Cells, 2020 Adipose-derived stromal/stem cells (ASCs) have been shown to exert regenerative functions, which are mainly attributed to the secretion of trophic factors. Upon transplantation, ASCs are facing an ischemic environment characterized by oxygen and nutrient
Julia Bachmann +6 more
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