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Differential glucose repression in common yeast strains in response to HXK2 deletion [PDF]
Under aerobic, high glucose conditions, Saccharomyces cerevisiae exhibits glucose repression and thus a predominantly fermentative metabolism. Here, we show that two commonly used prototrophic representatives of the CEN.PK and S288C strain families ...
Anne Kümmel +2 more
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Glucose repression of the Kluyveromyces lactis invertase gene KlINV1 does not require Mig1p
Kluyveromyces lactis, a budding yeast related to Saccharomyces cerevisiae, can grow on a wider variety of substrates and shows less sensitivity to glucose repression than does Saccharomyces cerevisiae. Many genes that are subject to glucose repression in
J Vandenhaute
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Carbon catabolite repression: not only for glucose
Current Genetics, 2019Most organisms prefer to utilize glucose as a carbon source. Accordingly, the expression of genes involved in the catabolism of other carbon sources is repressed by the presence of glucose in a process known as (carbon) catabolite repression. However, much less is known about the relationships between "poor" carbon sources.
Kobi Simpson-Lavy, Martin Kupiec
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Mitochondrial DNA and glucose repression in yeast
Biochemical and Biophysical Research Communications, 1972Abstract The amount of mitochondrial DNA, oxygen uptake, cytochrome content and number of mitochondria were examined in Saccharomyces carlsbergensis subjected to various degrees of glucose repression in chemostate cultures. The proportion of mitochondrial DNA varied from 11.5% of nuclear DNA in nonrepressed to 3.3% in repressed cells. Even at 0.
H S, Bleeg +4 more
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The role of hormones in glucose repression in rat liver
Advances in Enzyme Regulation, 1969Abstract Previous studies from this laboratory have demonstrated that the admin istration of amino acid mixtures to rats previously fed a 0% protein diet will markedly induce the synthesis of several hepatic enzymes. In particular, serine dehydratase is markedly induced under these conditions.
H D, Söling +3 more
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Trends in Genetics, 1995
In many organisms, glucose represses genes that are used to metabolize other carbon sources. Work in yeast and filamentous fungi has revealed a mechanism for glucose repression in eukaryotes that is different from that found in bacteria. Zinc finger proteins, such as Mig1 and CREA, that bind GC-boxes play a key role in mediating this response.
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In many organisms, glucose represses genes that are used to metabolize other carbon sources. Work in yeast and filamentous fungi has revealed a mechanism for glucose repression in eukaryotes that is different from that found in bacteria. Zinc finger proteins, such as Mig1 and CREA, that bind GC-boxes play a key role in mediating this response.
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Construction of glucose-repressible yeast expression vectors
Gene, 1993A set of two episomal yeast expression vectors, pYME1 and pYME2, were constructed. These Saccharomyces cerevisiae-Escherichia coli shuttle vectors each contain a modified yeast MAL6S (encoding maltase) promoter that is expressed constitutively, but is subject to carbon catabolite repression by glucose.
B, Yao, J, Marmur, P, Sollitti
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Hexose phosphorylation was studied in Aspergillus nidulans wild-type and in a fructose non-utilising mutant (frA). The data indicate the presence of at least one hexokinase and one glucokinase in wild-type A.
George J G Ruijter +2 more
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GLUCOSE REPRESSION OF OXIDATION OF ORGANIC COMPOUNDS BY SPHAEROTILUS
Canadian Journal of Microbiology, 1967Sphaerotilus discophorus and Sphaerotilus natans, when grown in media containing glucose, exhibit a very limited capacity to oxidize sugars, amino acids, and compounds of the tricarboxylic acid cycle. However, when grown in the absence of glucose, these species oxidize the above compounds rapidly and extensively.
J L, Stokes, M T, Powers
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Isolation and characterization of a Neurospora glucose-repressible gene
Current Genetics, 1988Using differential hybridization, the cDNA copy of a Neurospora gene coding for an abundant glucose-repressible mRNA (grg-1) has been isolated. The cDNA was used to clone the genomic copy, and both were sequenced. The cDNA is nearly full length and contains putative translational start and termination codons. Conceptual translation indicates that grg-1
M T, McNally, S J, Free
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