Results 51 to 60 of about 2,049,261 (287)

Glucose Variability: Where It Is Important and How to Measure It [PDF]

Diabetes, 2013
Glucose variability predicts hypoglycemia in both type 1 and type 2 diabetes and has consistently been related to mortality in nondiabetic patients in the intensive care unit. SD and mean amplitude of glycemic excursions have historically been very popular measures of glucose variability.
openaire   +2 more sources

Perioperative Hyperglycemia and Glucose Variability in Gynecologic Laparotomies [PDF]

Journal of Diabetes Science and Technology, 2015
Background: The glycemic response and its relation to postoperative complications following gynecologic laparotomies is unknown, although these surgeries carry a substantial risk for postoperative morbidity.
Polderman, Jorinde A. W., Hollmann, Markus W., DeVries, J. Hans, Preckel, Benedikt, Hermanides, Jeroen   +4 more
openaire   +3 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Estimation of insulin sensitivity from continuous glucose monitoring and insulin pump data in type 1 diabetes [PDF]

, 2012
Diabetes mellitus is a disease characterized by chronic hyperglycemia either due to a lack of secretion of the hormone insulin (Type 1 Diabetes Mellitus, T1DM) or due to impaired action of this hormone (Type 2 Diabetes Mellitus, T2DM).
Ronca, Gabriele
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

A moderately higher time-in-range threshold improves the prognosis of type 2 diabetes patients complicated with COVID-19

Frontiers in Endocrinology
ObjectiveAfter fully lifting coronavirus disease 2019 (COVID-19) pandemic control measures in mainland China in 12/2022, the incidence of COVID-19 has increased markedly, making it difficult to meet the general time-in-range (TIR) requirement.
Riping Cong, Jianbo Zhang, Jianbo Zhang, Lujia Xu, Yujian Zhang, Hao Wang, Jing Wang, Wei Wang, Yingli Diao, Haijiao Liu, Jing Zhang, Kuanxiao Tang   +11 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Glycemic Variability Before and After Hypoglycemia Across Different Timeframes in Type 1 Diabetes with and Without Automated Insulin Delivery

Diabetology
Background: Managing Type 1 diabetes (T1D) aims to optimize glucose within the target range while minimizing hyperglycemia and hypoglycemia, yet exercise complicates glycemic outcomes.
Ahtsham Zafar, Abiodun A. Solanke, Dana M. Lewis, Arsalan Shahid   +3 more
doaj   +1 more source

Effects of Variability in Glycemic Indices on Longevity in Chinese Centenarians

Frontiers in Nutrition, 2022
BackgroundLarge fluctuations in blood glucose levels greatly impact the health and life span of elderly individuals. This study describes the characteristics of variability in glycemic indices in centenarians with the aim of emphasizing the importance of
Sheng-han Ji, Sheng-han Ji, Chen Dong, Rou Chen, Rou Chen, Chen-chen Shen, Jing Xiao, Yun-juan Gu, Yun-juan Gu, Jian-lin Gao   +9 more
doaj   +1 more source

Glucose variability and mood in adults with diabetes: A systematic review [PDF]

Endocrinology, Diabetes & Metabolism, 2020
AbstractAimsTo systematically review the literature regarding the association between glucose variability (GV) and mood in adults with diabetes, appraise the used methods and make suggestions for future research.MethodsA systematic review of literature published up to May 2019 was performed.
Linda T. Muijs, Caterina Racca, Maartje de Wit, Annelies Brouwer, Thomas H. Wieringa, Ralph de Vries, Erik H. Serné, Daniël H. van Raalte, Femke Rutters, Frank J. Snoek   +9 more
openaire   +4 more sources