Results 91 to 100 of about 39,507 (336)
Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. family GH3 β-D-glucosidases [PDF]
The industrial conversion of cellulosic plant biomass into useful products such as biofuels is a major societal goal. These technologies harness diverse plant degrading enzymes, classical exo- and endo-acting cellulases and, increasingly, cellulose ...
Agirre+55 more
core +2 more sources
Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives
ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos+8 more
wiley +1 more source
Molecular characterization and heterologous expression of a Xanthophyllomyces dendrorhous ¿-glucosidase with potential for prebiotics production [PDF]
Basidiomycetous yeast Xanthophyllomyces dendrorhous expresses an α-glucosidase with strong transglycosylation activity producing prebiotic sugars such as panose and an unusual tetrasaccharides mixture including α–(1–6) bonds as major products, which ...
Fernández Lobato, María+5 more
core +1 more source
Abstract An infusion of Ageratina grandifolia, a traditional preparation, and major compounds [3,5‐diprenyl‐4‐hydroxyacetophenone (1), O‐methylencecalinol (2), encecalin (3), and encecalinol (4)], tested at 10, 31.6, and 100 mg/kg, intragastrically administered, showed a significant antinociceptive effect in both phases of the formalin test in mice ...
José Alberto Gutiérrez‐González+5 more
wiley +1 more source
New records of potent in-vitro antidiabetic properties of Dalbergia tonkinensis heartwood and the bioactivity-guided isolation of active compounds [PDF]
[[abstract]]Alpha-glucosidase inhibitory activity has been commonly used for the evaluation of antidiabetic property in vitro. The aim of this study is to investigate and characterize Dalbergia tonkinensis as a potential source of antidiabetic compounds.
Aguiree+12 more
core +1 more source
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves+3 more
wiley +1 more source
Iminosugar inhibitors of carbohydrate-active enzymes that underpin cereal grain germination and endosperm metabolism [PDF]
Starch is a major energy store in plants. It provides most of the calories in the human diet and, as a bulk commodity, it is used across broad industry sectors.
Alison M. Smith+57 more
core +2 more sources
Essential oil from Cinnamomum camphora leaves: Chemical profiling using FTIR analysis and bioactivity assessment for diverse bio‐pharmaceutical applications. ABSTRACT This study explores key biopharmaceutical properties of Cinnamomum camphora essential oil (EO), including antioxidant, anti‐enzymatic, and antifungal activities, and evaluates its minimum
Maroua Cheribot Cherif+6 more
wiley +1 more source
Acarbose impairs gut Bacteroides growth by targeting intracellular glucosidases
Acarbose is a type 2 diabetes medicine that prevents dietary starch breakdown into glucose by inhibiting host amylase and glucosidase enzymes. Numerous gut species in the Bacteroides genus enzymatically break down starch and change in relative abundance ...
Haley A. Brown+6 more
doaj +1 more source