Results 11 to 20 of about 39,507 (336)
Peptide modulators of alpha‐glucosidase [PDF]
Journal of Diabetes Investigation, 2015 AbstractAims/IntroductionAcute glucose fluctuations during the postprandial period pose great risk for cardiovascular complications and thus represent an important therapeutic approach in type 2 diabetes. In the present study, screening of peptide libraries was used to select peptides with an affinity towards mammalian intestinal alpha‐glucosidase as ...
Irena Roskar +5 more
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-Glucosidase Activity in Mycoplasma [PDF]
Journal of General Microbiology, 1964 Summary: Strains of three groups of Mycoplasma with different nutritional requirements were analysed for β-glucosidase activity. The enzyme was found in the cell membrane of Mycoplasma laidlawii strain b and M. gallisepticum strain J, which metabolize carbohydrates; negligible β-glucosidase activity was found in M.
C. V. Henrikson, P. F. Smith
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Mechanism of activation of glucocerebrosidase by CO-β-glucosidase (glucosidase activator protein) [PDF]
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1981 The nature of the stimulatory action of the protein 'coglucosidase' on glucocerebrosidase was investigated with the use of highly purified cofactor from bovine spleen, radioactive glucosyl ceramide and methylumbelliferyl-beta-glucoside. A complex between glucosidase and either substrate could not be detected under equilibrium and non-equilibrium ...
Berent, Susan L., Radin, Norman S.
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Beta-glucosidase 1 (GBA1) is a second bile acid β-glucosidase in addition to β-glucosidase 2 (GBA2). Study in β-glucosidase deficient mice and humans [PDF]
Biochemical and Biophysical Research Communications, 2012 Beta-glucosidase 1 (GBA1; lysosomal glucocerebrosidase) and β-glucosidase 2 (GBA2, non-lysosomal glucocerebrosidase) both have glucosylceramide as a main natural substrate. The enzyme-deficient conditions with glucosylceramide accumulation are Gaucher disease (GBA-/- in humans), modelled by the Gba-/- mouse, and the syndrome with male infertility in ...
Harzer, Klaus +6 more
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Interaction of antidiabetic α‐glucosidase inhibitors and gut bacteria α‐glucosidase [PDF]
Protein Science, 2018 AbstractCarbohydrate hydrolyzing α‐glucosidases are commonly found in microorganisms present in the human intestine microbiome. We have previously reported crystal structures of an α‐glucosidase from the human gut bacterium Blaubia (Ruminococcus) obeum (Ro‐αG1) and its substrate preference/specificity switch.
Christine Tesar +4 more
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Transglucosylation of a-Glucosidase
Journal of the Japanese Society of Starch Science, 1979 a-Glucosidases which are essentially hydrolase have been found to catalyze also the trans-glucosylation which means the transfer action on the acceptors other than water. The action patterns of some a-glucosidases were compared with one another. Sacch. logos a-glucosidase, an a-1, 6-transglucosylase, showed the transfer activity of a glucosyl moiety to
Seiya Chiba, Tokuji Shimomura
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Frontiers in Microbiology, 2022 Three β-glucosidases from Bifidobacterium adolescentis ATCC15703, namely, BaBgl1A, BaBgl3A, and BaBgl3B, were overexpressed in Escherichia coli. The recombinant β-glucosidases were sufficiently purified using Ni2+ affinity chromatography, and BaBgl1A ...
Yanbo Hu +6 more
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Crystal Structure of Thermotoga maritima α-Glucosidase AglA Defines a New Clan of NAD+-dependent Glycosidases [PDF]
, 2003 Glycoside hydrolase family 4 represents an unusual group of glucosidases with a requirement for NAD(+), divalent metal cations, and reducing conditions. The family is also unique in its inclusion of both alpha- and beta-specific enzymes.
Hoffmann, Volker +4 more
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Biochemical characterization of digestive carbohydrases in Moroccan locust, Dociostaurus maroccanus Thunberg (Orthoptera: Acrididae) [PDF]
Arthropods, 2020 The Moroccan locust, Dociostaurus maroccanus (Thunberg), is an agricultural pest which has caused considerable agricultural damage and economic importance.
Bahareh Rafiei +2 more
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