Results 191 to 200 of about 11,448 (264)

Efficacy and safety of switching to iGlarLixi from premixed insulin therapy in patients with type 2 diabetes: A real‐world experience

Diabetic Medicine, Volume 43, Issue 7, July 2026.
Abstract Aims Fixed‐ratio combinations such as iGlarLixi are recommended over premixed insulin as first‐line injectable therapy for type 2 diabetes mellitus (T2DM), yet real‐world evidence on transitions from premix to iGlarLixi remains limited. This study aimed to evaluate the efficacy and safety of switching from premixed insulin to iGlarLixi in a ...
Chun‐Jui Huang, Shun‐Jie Yang, Cheng‐Pin Cheng, Chun‐Hsing Lin, Ya‐Chun Lee, Harn‐Shen Chen   +5 more
wiley   +1 more source

Comparison of active site mutations at subsite + 2 of Anoxybacillus ayderensis A9 β-glucosidase for hydrolysis of pNPG and polydatin. [PDF]

BMC Biotechnol
Zada NS, Belduz AO, Alessa AH, Güler HI, Karaoğlan M, Badshah M, Shah AA, Kalsoom A, Khan S.   +8 more
europepmc   +1 more source

A systematic review and meta‐analysis of the relative benefit of dual versus single oral hypoglycaemic therapy following diagnosis with type 2 diabetes (T2D)

Diabetic Medicine, Volume 43, Issue 7, July 2026.
Abstract Introduction Achieving and sustaining target glycated haemoglobin (HbA1c) levels is fundamental in the management of type 2 diabetes (T2D). We here aimed to assess whether initial dual oral therapy outperforms monotherapy in reaching glycaemic targets in patients with treatment‐naive or early‐stage T2D.
Mairead Kelly, Sushant Saluja, Hugh Logan Ellis, Sarah Jamil, Martin B. Whyte, Adrian Heald   +5 more
wiley   +1 more source

Improvement of the capacity to hydrolyze corncob residues through deciphering the lignocellulolytic enzyme system of a hyper-cellulolytic mutant strain Trichoderma reesei CU7-4. [PDF]

Biotechnol Biofuels Bioprod
Wang Y, Li K, Li M, Lv S, Wang Y, Liu H, Zhong Y.   +6 more
europepmc   +1 more source

Impact of Simulated Risk Factor Management on Cardiovascular Disease and Costs in Type 2 Diabetes Using the ABC Model

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5670-5683, July 2026.
ABSTRACT Aims We evaluated the impact of scenario‐based multifactorial control on the 3‐year incidence of fatal/non‐fatal cardiovascular disease (CVD) and associated healthcare costs in Asian patients with type 2 diabetes (T2D). Materials and Methods We applied the validated ‘ABC’ model to simulate the 3‐year impact of attaining multiple treatment ...
Lee‐Ling Lim, Eric S. H. Lau, Juliana N. M. Lui, Linong Ji, A. G. Unnikrishnan, Sirinart Sirinvaravong, Siew‐Pheng Chan, Soo Lim, Andrea O. Y. Luk, Juliana C. N. Chan   +9 more
wiley   +1 more source

Impact of Changes in Buffer Ionic Concentration and Mutations on a GH1 β‑Glucosidase Homodimer. [PDF]

ACS Omega
Chagas RS, Marana SR.
europepmc   +1 more source

Bifidobacterium bifidum G9‐1 Intake Improves Gastrointestinal Symptoms in Type 2 Diabetes Mellitus: An Open‐Label, Randomized Controlled Trial (Binary STAR Study)

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5952-5967, July 2026.
ABSTRACT Aims To evaluate the effects of probiotics Bifidobacterium bifidum G9‐1 (BBG9‐1) on gastrointestinal symptoms in patients with Type 2 diabetes mellitus (T2DM) with diarrhoea or constipation. Materials and Methods In a 12‐week open‐label randomised controlled trial, 100 participants were randomized 1:1 to a control or BBG9‐1 group, with 12 mg ...
Genki Kobayashi, Yoshitaka Hashimoto, Tomoyuki Matsuyama, Noriyuki Kitagawa, Saori Majima, Takafumi Senmaru, Emi Ushigome, Hiroshi Okada, Naoko Nakanishi, Masahide Hamaguchi, Michiaki Fukui   +10 more
wiley   +1 more source

Long‐Term Cultivation of Perennial Energy Crops Enhance Ecosystem Multifunctionality on Marginal Red Soil Without Trade‐Offs

GCB Bioenergy, Volume 18, Issue 7, July 2026.
Switchgrass (SG) and Miscanthus (MS) boost ecosystem multifunctionality in marginal soils. Strong synergies, not trade‐offs, exist among ecosystem services under SG and MS. MS surpasses SG in provisioning and supporting services for higher multifunctionality. MS is ideal for maximizing multifunctionality, carbon sequestration, and stability.
Yini Wu (伍旖旎), Yi Xu (许依), Tongcheng Fu (傅童成), Meng Li (李蒙), Moritz von Cossel, Grant Campbell, Pete Smith, Yasir Iqbal, Zili Yi (易自力), Shuai Xue (薛帅)   +9 more
wiley   +1 more source

Genomic and Transcriptomic Analyses Provide Insights Into Erysiphe necator Pathogenicity and Grapevine Response

Plant Biotechnology Journal, Volume 24, Issue 7, Page 4599-4618, July 2026.
ABSTRACT Grapevine powdery mildew, caused by the fungus Erysiphe necator, is one of the most prevalent obligate biotrophic pathogens in vineyards, posing a significant threat to grape production. Despite its impact, research on E. necator pathogenicity and grapevine responses remains limited.
Bo Mu, Ruixin Tang, Zhaolin Teng, Jinfu Chen, Kaicheng Cui, Feng Wei, Wenxiang Kong, Shunyuan Xiao, Xiangnan Xu, Jia‐Yue Feng, Ying‐Qiang Wen   +10 more
wiley   +1 more source

Tolerance to Phosphorus Deficiency Improves Seed Phytic Acid‐to‐Iron Molar Ratios in Common Bean

Plant, Cell &Environment, Volume 49, Issue 7, Page 4152-4165, July 2026.
ABSTRACT Although significant advances have been achieved in the biofortification of common beans to overcome deficiencies in Zinc (Zn) and iron (Fe), the mechanisms involved remain poorly understood. We thus explored the relationships between phosphorus nutrition and Zn and Fe accumulation in four bean genotypes (Edar, Nizok, Colorado and Chimbolos ...
Barbara Karpinska, Christine H. Foyer
wiley   +1 more source