Synthesis and in vivo evaluation of non-hepatotoxic acetaminophen analogs [PDF]
A series of acetaminophen (APAP) analogs, 2-(1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)-N-(4-hydroxyphenyl)alkanecarboxamides, bearing a heterocyclic moiety linked to the p-acylaminophenol fragment, were prepared in a general project to develop APAP ...
Bazan, Nicolas G. +11 more
core +3 more sources
Glucuronoyl Esterase Screening and Characterization Assays Utilizing Commercially Available Benzyl Glucuronic Acid Ester [PDF]
Research on glucuronoyl esterases (GEs) has been hampered by the lack of enzyme assays based on easily obtainable substrates. While benzyl d-glucuronic acid ester (BnGlcA) is a commercially available substrate that can be used for GE assays, several ...
Charavgi, M. D. +4 more
core +2 more sources
Plausible role of estrogens in pathogenesis, progression and therapy of lung cancer [PDF]
Malignant neoplasms are among the most common diseases and are responsible for the majority of deaths in the developed world. In contrast to men, available data show a clear upward trend in the incidence of lung cancer in women, making it almost as ...
Baczek T. +9 more
core +1 more source
The Glycobiome of the Rumen Bacterium Butyrivibrio proteoclasticus B316T Highlights Adaptation to a Polysaccharide-Rich Environment [PDF]
Determining the role of rumen microbes and their enzymes in plant polysaccharide breakdown is fundamental to understanding digestion and maximising productivity in ruminant animals.
Altermann, Eric +11 more
core +4 more sources
O-Sulfated Derivatives of Glucuronic Acid [PDF]
4-O-Substituted D-glucuronic acid derivatives were synthesized from D-glucose in order to study the regioselectivity of sulfation.
Castro, M.J.L. +3 more
openaire +5 more sources
Herbal medicine has taken a prominent place in the North African skincare system because of the increased installation of herbalists and healers, but unfortunately most of these do not have the required level to practice this medicine.
Rachid, Djafer
core +2 more sources
Glucuronate, the precursor of vitamin C, is directly formed from UDP‐glucuronate in liver [PDF]
The conversion of UDP‐glucuronate to glucuronate, usually thought to proceed by way of glucuronate 1‐phosphate, is a site for short‐term regulation of vitamin C synthesis by metyrapone and other xenobiotics in isolated rat hepatocytes [Linster CL & Van Schaftingen E (2003) J Biol Chem278, 36328–36333].
Emile Van Schaftingen, Carole L. Linster
openaire +3 more sources
High‐Yield Production, Characterization, and Functionalization of Recombinant Magnetosomes in the Synthetic Bacterium Rhodospirillum rubrum “magneticum” [PDF]
Recently, the photosynthetic Rhodospirillum rubrum has been endowed with the ability of magnetosome biosynthesis by transfer and expression of biosynthetic gene clusters from the magnetotactic bacterium Magnetospirillum gryphiswaldense.
Mickoleit, Frank +6 more
core +2 more sources
Beer Polyphenols and Menopause: Effects and Mechanisms-A Review of Current Knowledge [PDF]
Beer is one of the most frequently consumed fermented beverages in the world, and it has been part of the human diet for thousands of years. Scientific evidence obtained from the development of new techniques of food analysis over the last two decades ...
Andree Sandoval-Ramirez, Berner +5 more
core +1 more source
Background As yet, the genetic abnormalities involved in the exacerbation of Ulcerative colitis (UC) have not been adequately explored based on bioinformatic methods. Materials and methods The gene microarray data and clinical information were downloaded
Yao Wang +5 more
semanticscholar +1 more source

