Results 111 to 120 of about 42,461 (214)

Modulation of Macrophage Inflammatory Responses by UDP-Glucuronosyltransferase-Mediated PGE₂ Glucuronidation. [PDF]

J Pers Med
Lee D, Cho HY, Ahn S, Cho YS, Kim DH, Shin JG, Lee SJ.   +6 more
europepmc   +1 more source

Multiscale zonation-resolved modeling of dose-dependent determinants of acetaminophen-induced liver injury. [PDF]

Front Pharmacol
Ghosh D, Camara Dit Pinto S, Malka-Markovitz A, Cherkaoui M, Sadeghi R, Vierling JM, Gallo NR.   +6 more
europepmc   +1 more source

Cross-species metabolic characterization of eutylone and mechanism-based inhibition of CYP2D6 and CYP2B6 with drug interaction implications. [PDF]

Sci Rep
Lee MS, Song IS, Jang Y, Cho YY, Lee JY, Kang HC, Kim JH, Lee HS.   +7 more
europepmc   +1 more source

The Impact of <i>UGT1A1</i> Genetic Variability on Enzyme Expression in Liver Pathology. [PDF]

Genes (Basel)
Szeląg-Pieniek S, Kucak J, Malinowski D, Oswald S, Droździk M, Kurzawski M.   +5 more
europepmc   +1 more source

Design, expression, purification, and application of novel recombinant miR-491 molecules to define the biogenesis and function of miR-491-3p versus -5p in posttranscriptional regulation of UDP-glucuronosyltransferase 1A1. [PDF]

Drug Metab Dispos
Wang Y, Tu MJ, Batra N, Guan S, Zhou Y, Yu AM.   +5 more
europepmc   +1 more source

An integrated strategy based on LC/MS for the systematic screening of loganin metabolites <i>in vivo</i>. [PDF]

RSC Adv
Wu P, Zhu H, Hu D, Tan Y, Yang S, Huang Y, Li K, Li H.   +7 more
europepmc   +1 more source

Stereoselective Biotransformation: Transfer of Learning to Advance Drug Metabolism and Biocatalysis. [PDF]

Angew Chem Int Ed Engl
Okunlola GA, Aleku GA.
europepmc   +1 more source

UGTformer: a pretrained graph transformer model for predicting UDP-glucuronosyltransferase-mediated drug metabolism. [PDF]

J Cheminform
Zhan M, Li X, Xiong L, Song W, Fang J, Liu G, Tang Y, Li W.   +7 more
europepmc   +1 more source

Exploring the pharmacokinetic mechanisms that affect bictegravir exposure during pregnancy. [PDF]

J Antimicrob Chemother
van der Wekken-Pas L, Hidalgo-Tenorio C, Rockstroh JK, van Bremen K, Richel O, Molto J, Lambert JS, de Kanter C, Konopnicki D, Burger D, Colbers A.   +10 more
europepmc   +1 more source

Characterization of the Formation of the Acyl Glucuronide Metabolite of 7-Carboxy-Cannabidiol in Human Liver, Kidney, and Intestinal Microsomes and <i>in Vivo</i> in Mice. [PDF]

ACS Med Chem Lett
Simon KT, Hailemariam SE, Friedman E, Wen YW, Freaney M, Barker-Haliski M, Isoherranen N.   +6 more
europepmc   +1 more source