Results 101 to 110 of about 42,461 (214)
eFood, Volume 7, Issue 4, August 2026.This review aims to evaluate the anti‐inflammatory potential of these spice blends, emphasizing their synergistic mechanisms, and to investigate how cultivation practices, post‐harvest processing, and environmental stressors shape their medicinal efficacy. By addressing this gap, it seeks to provide a comprehensive framework for integrating traditional
Qudrat Ullah +5 more
wiley +1 more source
The Journal of Clinical Pharmacology, Volume 66, Issue 8, August 2026.Abstract Spaceflight induces altered physiology that has the potential to alter medication pharmacokinetics due to factors including gastrointestinal motility, fluid balance, circulatory dynamics, hormonal changes, and metabolic alterations. Here, we report the first pharmacokinetic analysis using blood samples during spaceflight.
David Mampre +13 more
wiley +1 more source
Uptake and Transport of Monotropein and Monotropein Esters in a Caco‐2/HT29‐MTX‐E12 Co‐Culture Model
Molecular Nutrition &Food Research, Volume 70, Issue 15, 17 August 2026.Monotropein and its naturally occurring ester derivatives (monotropein‐10‐coumarate and monotropein‐10‐cinnamate) from Gaultheria spp. berries exhibit limited intestinal permeability in a validated Caco‐2:HT29‐MTX‐E12 co‐culture model. Absorption occurs predominantly via passive diffusion, with partial SGLT1‐ and OATP‐mediated uptake contribution for ...
Christian Zielinski +7 more
wiley +1 more source
Molecular Nutrition &Food Research, Volume 70, Issue 16, 27 August 2026.Possible immunomodulatory effects of caffeic acid on BALB/cnu mice subcutaneously loaded with HT‐29 cells. ABSTRACT The effects of caffeic acid (CA) intervention on the relationship between human colorectal cancer (CRC) HT‐29 cell growth and Th1/Th2 immune balance in vivo are not fully understood.
Hsuan‐Yin Chen +3 more
wiley +1 more source
Could NAPQI Contribute to Paracetamol Analgesia? Redox Modulation of Kv7 Ion Channels
Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.ABSTRACT Paracetamol (acetaminophen, APAP) is one of the most widely used analgesic and antipyretic drugs worldwide, yet its mechanism of action remains incompletely understood. While several pathways have been proposed, including cyclooxygenase inhibition and endocannabinoid modulation via AM404, none fully account for its pharmacological profile. The
Sara M‐Alicante +6 more
wiley +1 more source
Clinical and Translational Science, Volume 19, Issue 8, August 2026.ABSTRACT Given the increasing prevalence of postpartum depression (PPD) and the stigma associated with this condition, it is essential to address this significant health concern. Brexanolone is an FDA‐approved treatment for PPD that works by positive‐allosteric modulation of type A γ‐aminobutyric acid (GABAA) receptors.
Laura Gayanova +4 more
wiley +1 more source
Characterization of Atrasentan Metabolic Pathway in Human Liver Microsomes Using Feature-Based Molecular Networking. [PDF]
PharmaceuticsSeo HJ, Liang Z, Kim EH, Liu KH.
europepmc +1 more source
Dexamethasone-Mediated Regulation of CYP3A4 and UGTs in Human Hepatoma HuH-7 Cells. [PDF]
Fundam Clin PharmacolYu H, Lee SH, Kim JH, Kim SJ, Kang HE.
europepmc +1 more source