Results 91 to 100 of about 56,416 (247)

Identification of the Biotransformation Products of 2-Ethylhexyl 4-(N,N-Dimethylamino)benzoate [PDF]

, 2009
Nowadays, 2-ethylhexyl 4-(N,N-dimethylamino)benzoate (EDP) is one of the most widely used UV filters in sunscreen cosmetics and other cosmetic products.
Zacarias León, Jon Vlieger, Alberto Chisvert, Amparo Salvador, Henk Lingeman, Hubertus Irth, Martin Giera, JM Norris, P Kullavanijaya, S Lautenschlager, S Gonzalez, VE Reeve, C Kerr, C Couteau, R Roelandts, M Schlumpf, RS Ma, RHMM Schreurs, E Gomez, M Gulston, CX Xu, CGJ Hayden, GE Kenney, IH Blank, U Hagedorn-Leweke, CS Okereke, DL Giokas, L Vidal, A Balaguer, R Jiang, ND Brown, JM Allen, BS Mackie, SH Dromgoole, CF Chignell, AA Shaw, JC Sutherland, SR Aliwell, M Rooseboom, T Tanaka, F Gusson   +40 more
core   +4 more sources

Paracetamol prescribing to small animals by veterinarians in Australia and New Zealand

Australian Veterinary Journal, EarlyView.
Objective To describe the prescribing patterns of paracetamol by veterinarians in Australia and New Zealand. Methods An online survey was created and distributed to veterinarians in Australia and New Zealand over a 3‐month period (July–October 2024).
A Tse, W Chee, CJ Boyd, CR Sharp
wiley   +1 more source

Paediatric clinical pharmacology in the UK [PDF]

, 2014
Paediatric clinical pharmacology is the scientific study of medicines in children and is a relatively new subspecialty in paediatrics in the UK. Training encompasses both the study of the effectiveness of drugs in children (clinical trials) and aspects ...
Choonara, Imti, Sammons, Helen
core   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source

Insights into the Metabolism, Disposition, and Quantitative Profile of mGlu5 NAM AE90015 with Metabolite Identification and a Novel Integration Method

Molecules
AE90015 is a highly specific and effective negative allosteric modulator (NAM) for the human mGlu5 receptor, showing significant promise for treating Parkinson’s disease.
Zhiyang Zack Zou, Ming-Jie Han, Yu Chang, Guiying Li   +3 more
doaj   +1 more source

A Review of Nonsteroidal Anti‐Inflammatory Drugs for Food‐Producing Animals With a Focus on Potential Applications for Farmed Finfish

Journal of Fish Diseases, EarlyView.
ABSTRACT In finfish aquaculture, there are several inflammatory diseases impacting productivity and animal welfare, however there are limited options available to veterinarians to treat inflammation and pain in fish. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used in terrestrial animals raised for human consumption to treat a range of ...
Chloe J. English, Christine Huynh, William Roy, James W. Wynne, Hamish Rodger   +4 more
wiley   +1 more source

The role of mycotoxins in pig reproduction : a review [PDF]

, 2009
Mycotoxins are commonly present in feed for farm animals. Sows and gilts are highly susceptible to mycotoxins. This article presents a review describing the main mycotoxins encountered in pig feed which have a negative impact on sow fertility and ...
Kanora, Alain, Maes, Dominiek
core  

Age- and therapy-related effects on morphine requirements and plasma concentrations of morphine and its metabolites in postoperative infants [PDF]

, 2003
BACKGROUND: To investigate clinical variables such as gestational age, sex, weight, the therapeutic regimens used and mechanical ventilation that might affect morphine requirements and plasma concentrations of morphine and its ...
Anand, K.J.S. (Kanwaljeet), Anker, J.N. (John) van den, Bouwmeester, J. (Nancy), Hop, W.C.J. (Wim), Tibboel, D. (Dick)   +4 more
core   +3 more sources

Influence of Tramadol on the Intravenous Pharmacokinetics of Dipyrone Active Metabolites in Dogs

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT This study aimed to compare the pharmacokinetic profile of the active dipyrone metabolites 4‐methylaminoantipyrine (MAA) and 4‐aminoantipyrine (AA) administered alone and in combination with tramadol in dogs. Nine mixed‐breed dogs, weighing 15.33 ± 2.25 kg, participated in a two‐treatment crossover design: G1 received intravenous dipyrone (25 ...
Andressa Nunes Mouta, Kathryn Nóbrega Arcoverde, Robson dos Anjos Honorato, Naftáli Silva Fernandes, Caio Vinicius Almeida de Oliveira, Glícia Cavalcante Mesquita, Yanna Deysi Bandeira Passos, Gabriel Araújo‐Silva, Valéria Veras de Paula   +8 more
wiley   +1 more source

Adaptive evolution of multiple-variable exons and structural diversity of drug-metabolizing enzymes [PDF]

, 2007
Background The human genome contains a large number of gene clusters with multiple-variable-first exons, including the drug-metabolizing UDP glucuronosyltransferase (UGT1) and I-branching β-1,6-N-acetylglucosaminyltransferase (GCNT2, also known as IGNT ...
Wu Qiang, Li Can
core   +2 more sources