Results 141 to 150 of about 41,898 (332)

A Review of Nonsteroidal Anti‐Inflammatory Drugs for Food‐Producing Animals With a Focus on Potential Applications for Farmed Finfish

Journal of Fish Diseases, EarlyView.
ABSTRACT In finfish aquaculture, there are several inflammatory diseases impacting productivity and animal welfare, however there are limited options available to veterinarians to treat inflammation and pain in fish. Nonsteroidal anti‐inflammatory drugs (NSAIDs) are widely used in terrestrial animals raised for human consumption to treat a range of ...
Chloe J. English, Christine Huynh, William Roy, James W. Wynne, Hamish Rodger   +4 more
wiley   +1 more source

Efflux transport of estrogen glucuronides by human MRP2, MRP3, MRP4 and BCRP.

Journal of Steroid Biochemistry and Molecular Biology, 2017
Erkka Järvinen, Feng Deng, H. Kidron, M. Finel   +3 more
semanticscholar   +1 more source

Pharmacokinetics of a Single Subcutaneous Extended‐Release Buprenorphine (Ethiqa XR) in Healthy Beagles

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT This study evaluated the pharmacokinetics of an extended‐release buprenorphine formulation (Ethiqa XR) in dogs and explored potential sex differences. Twelve healthy intact beagles (6 males and 6 females) received a single subcutaneous injection of Ethiqa XR (0.2 mg/kg).
Kornelia Tiffinger, Hiroko Enomoto, Ronald E. Baynes, Laura M. Neumann, B. Duncan X. Lascelles, Masataka Enomoto   +5 more
wiley   +1 more source

Auxin‐Dependent Activation of RHD6‐RSL4 Cascade Promotes Root Hair Growth Under Boron Deficiency in Arabidopsis Primary Root Apices

Plant, Cell &Environment, EarlyView.
ABSTRACT Plants rapidly adjust their root system architecture to enhance resource uptake and cope with fluctuating soil environments. One such adaptive response is the development of root hairs (RH), which increase the effective root surface area and thereby improve water and nutrient acquisition.
Cristina Bahamonde, Clara de la Osa, Jesús Rexach, M. Begoña Herrera‐Rodríguez, Victoria Berdion Gabarain, José Manuel Estevez, M. Teresa Navarro‐Gochicoa, Agustín González‐Fontes, Juan J. Camacho‐Cristóbal   +8 more
wiley   +1 more source

The effects of a (poly)phenol‐rich food intervention on markers of exercise‐induced inflammation and oxidative stress: A randomised controlled trial

Experimental Physiology, EarlyView.
Abstract This study examined whether consuming a (poly)phenol‐rich food before strenuous muscle‐damaging exercise can modify post‐exercise markers of inflammation and oxidative stress. Using a double‐blinded, randomised, placebo‐controlled, between‐subjects design, 26 recreationally active males (n = 15) and females (n = 11) consumed higher‐(poly ...
Abrar Al Hebshi, Josh Thorley, Ana Rodriguez‐Mateos, Zicheng Zhang, Lewis J James, Tom Clifford   +5 more
wiley   +1 more source

Analysis of cannabinoids in oral fluid by liquid chromatography-tandem mass spectrometry [PDF]

, 2018
A sensitive method was developed for quantifying a wide range of cannabinoids in oral fluid (OF) by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Fabritius, Marie, Giroud, Christian, Mangin, Patrice, Staub, Christian   +3 more
core  

Physiological and anatomical determinants of placental drug transfer

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis, Anandita Umapathy, Jane K. Cleal, Bram G. Sengers   +3 more
wiley   +1 more source

Stereoselective Inhibition of Methotrexate Excretion by Glucuronides of Nonsteroidal Anti-inflammatory Drugs via Multidrug Resistance Proteins 2 and 4

Journal of Pharmacology and Experimental Therapeutics, 2016
A. Kawase, Taiki Yamamoto, Sachiko Egashira, M. Iwaki   +3 more
semanticscholar   +1 more source

Transfer of paracetamol across the placenta and fetal blood–brain barriers and its safety for use in pregnancy

The Journal of Physiology, EarlyView.
Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley   +1 more source

Characterization of Grape Cane Stilbenoids and Their Photo‐Degradation Products by HPLC‐DAD Coupled With Trapped Ion Mobility Spectrometry and High‐Resolution Tandem Mass Spectrometry

Rapid Communications in Mass Spectrometry, Volume 40, Issue 15, 15 August 2026.
ABSTRACT Rationale Bioactive (E)‐stilbenoids in vine extracts are prone to light‐induced transformation into the respective (Z)‐isomers and further degradation products, often resulting in a loss of bioactivity. We sought to study stilbenoid degradation beyond that of the well‐researched resveratrol due to the high diversity of stilbenoids in nature ...
Paul Besrukow, Friederike A. Schnitker, Ralf Schweiggert, Christof B. Steingass   +3 more
wiley   +1 more source