The Dual Role of the Gut Microbiota in Cancer Chemoresistance
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi +3 more
wiley +1 more source
Hepatic uptake of estradiol-3-glucuronide and estradiol-3-sulfate-17β-glucuronide by human organic anion transporting polypeptides 1B1, 1B3, and 2B1. [PDF]
Li L +7 more
europepmc +1 more source
Microbiome‐Phytochemical Crosstalk Along the Gut‐Brain Axis in Alzheimer and Parkinson's Disease
Phytochemicals remodel the gut microbiota by enriching beneficial bacteria and microbial metabolites while suppressing dysbiosis and inflammation. Through modulation of the gut–brain axis, they restore intestinal barrier integrity, regulate neuroimmune and neuroprotective signaling pathways, reduce amyloid‐β, tau, and α‐synuclein pathology, and ...
Md. Emon +6 more
wiley +1 more source
Recurrent <i>SLCO1B1</i> and <i>SLCO1B3</i> mutations identified in three patients with Rotor syndrome. [PDF]
Zhao C, Huang H.
europepmc +1 more source
Uptake and Transport of Monotropein and Monotropein Esters in a Caco‐2/HT29‐MTX‐E12 Co‐Culture Model
Monotropein and its naturally occurring ester derivatives (monotropein‐10‐coumarate and monotropein‐10‐cinnamate) from Gaultheria spp. berries exhibit limited intestinal permeability in a validated Caco‐2:HT29‐MTX‐E12 co‐culture model. Absorption occurs predominantly via passive diffusion, with partial SGLT1‐ and OATP‐mediated uptake contribution for ...
Christian Zielinski +7 more
wiley +1 more source
Efflux and uptake transport and gut microbial reactivation of raloxifene glucuronides. [PDF]
Uoti A +7 more
europepmc +1 more source
Possible immunomodulatory effects of caffeic acid on BALB/cnu mice subcutaneously loaded with HT‐29 cells. ABSTRACT The effects of caffeic acid (CA) intervention on the relationship between human colorectal cancer (CRC) HT‐29 cell growth and Th1/Th2 immune balance in vivo are not fully understood.
Hsuan‐Yin Chen +3 more
wiley +1 more source
Potential Modulation of Polygoni Cuspidati Rhizoma et Radix on Breast Cancer Resistance Protein and Marked Alteration on Methotrexate Pharmacokinetics. [PDF]
Hou YC +5 more
europepmc +1 more source
Urban waterways are important reservoirs and transmission pathways for antimicrobial resistance (AMR), but AMR measurements are not routine in water quality monitoring. This two‐year environmental study investigated the prevalence, diversity and surveillance potential of AMR Escherichia coli in the Ōtākaro/Avon River and tributaries in Ōtautahi ...
Sophie van Hamelsveld +8 more
wiley +1 more source
Advancements in curcuminoid formulations: An update on bioavailability enhancement strategies curcuminoid bioavailability and formulations. [PDF]
Darmonkow A, Rowe ZEM, Harding SV.
europepmc +1 more source

