Results 211 to 220 of about 41,898 (332)

Dexamethasone‐Mediated Regulation of CYP3A4 and UGTs in Human Hepatoma HuH‐7 Cells

Fundamental &Clinical Pharmacology, Volume 40, Issue 3, May 2026.
ABSTRACT Background The application of human hepatic cell lines to early drug discovery and development instead of human primary hepatocytes (HPHs) has been limited because of the low level of drug‐metabolizing enzymes (DMEs). Objective The study aimed to evaluate the effects of dexamethasone (DEX) treatment on DME expression, activities, and ...
Hana Yu, Song Hee Lee, Ji Hyeon Kim, Seung Jin Kim, Hee Eun Kang   +4 more
wiley   +1 more source

Building a predictive model for polycyclic aromatic hydrocarbon dosimetry in organotypically cultured human bronchial epithelial cells using benzo[<i>a</i>]pyrene. [PDF]

Toxicol Rep
Colvin VC, Bastin KM, Siddens LK, Vermillion Maier ML, Williams DE, Smith JN, Tilton SC.   +6 more
europepmc   +1 more source

Chromatography of anticancer drugs [PDF]

, 2013
Cserháti, Tibor, Szőgyi, Mária
core  

Human biomonitoring of mycotoxins: key challenges and future directions. [PDF]

Mycotoxin Res
Cramer B, Visintin L, Maris E, Kuhn M, Degen GH, Turner PC, Humpf HU, De Saeger S.   +7 more
europepmc   +1 more source

Chemical Isotope Labeling and Dual-Filtering Strategy for Comprehensive Profiling of Urinary Glucuronide Conjugates. [PDF]

Anal Chem
Chen ZQ, Yang RJ, Zhu CW, Li Y, Yan R, Wan JB.   +5 more
europepmc   +1 more source

Daidzein and genistein glucuronides in vitro are weakly estrogenic and activate human natural killer cells at nutritionally relevant concentrations.

Journal of NutriLife, 1999
Yan Zhang, T. Song, J. Cunnick, Patricia A. Murphy, S. Hendrich   +4 more
semanticscholar   +1 more source

Phenethylamine-derived designer drug diphenyl-2-pyrrolidinemethanol (D2PM) : Investigations of its biotransformation in rats [PDF]

, 2013
Schmitt, Sara Eva
core   +2 more sources

Chemopreventive Effects of Resveratrol and Curcumin on Melanoma Growth in C57BL/6 Mice. [PDF]

Asian Pac J Cancer Prev
Ul Islam S, Al Saidi A, Akbar S, Akhlaq A, Shehzad A, Ul-Islam M.   +5 more
europepmc   +1 more source

ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2.

Biochemical Journal, 1997
G. Jedlitschky, I. Leier, U. Buchholz, J. Hummel‐Eisenbeiss, B. Burchell, D. Keppler   +5 more
semanticscholar   +1 more source

In Silico Molecular Docking and Pharmacokinetic Evaluation of Cannabinoid Derivatives as Multi-Target Inhibitors for EGFR, VEGFR-1, and VEGFR-2 Proteins. [PDF]

Curr Issues Mol Biol
Ayoobi A, Choi HW.
europepmc   +1 more source