Results 71 to 80 of about 41,898 (332)
Agricultural Science, 2023 The study assessed the quality and safety parameters of poultry meat from two local producers. Broiler chicken carcasses, refrigerated and packed in polyethylene, were collected from the marketing network for laboratory evaluations at the Republican ...
Alisa PÎRLOG
doaj +1 more source
Systematic analysis of the polyphenol metabolome using the Phenol-Explorer database [PDF]
, 2017 SCOPE: The Phenol-Explorer web database details 383 polyphenol metabolites identified in human and animal biofluids from 221 publications. Here we exploit these data to characterize and visualize the polyphenol metabolome, the set of all metabolites ...
Andrés Lacueva, Ma. Cristina +9 more
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Green tea inhibited the elimination of nephro-cardiovascular toxins and deteriorated the renal function in rats with renal failure [PDF]
, 2015 Chronic kidney disease (CKD) is a major health problem worldwide. Indoxyl sulfate (IS) and p-cresyl sulfate (PCS) are highly protein-bound nephro-cardiovascular toxins, which are not efficiently removed through hemodialysis.
Chao, Pei-Dawn Lee +5 more
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IN VITRO IRREVERSIBLE BINDING AND DEGRADATION OF (R)- AND (S)-KETOPROFEN GLUCURONIDES TO PLASMA PROTEINS [PDF]
Malaysian Journal of Pharmaceutical Sciences, 2007 This study describes the in vitro degradation studies of the diastereomeric ketoprofen glucuronides, under physiological conditions (pH 7.4, 37°C, (R)-ketoprofen glucuronide t½ = 30 min, (S)-ketoprofen glucuronide t½ = 70 min) and the irreversible ...
PETER J. HAYBALL, KELLIE L. TUCK
doaj
Pharmaceutics, 2020 DWP16001 is currently in a phase 2 clinical trial as a novel anti-diabetes drug for the treatment of type 2 diabetes by selective inhibition of sodium-glucose cotransporter 2.
Ju-Hyun Kim +7 more
doaj +1 more source
, 2004 Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals.
Adlercreutz H +37 more
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British Journal of Clinical Pharmacology, EarlyView.Aim The aim of this study was to develop a novel workflow to identify human urine biomarkers for drugs of abuse and new psychoactive substances. Metabolites of amphetamine, cocaine, LSD, MDMA, methamphetamine, THC, MDMB‐CHMICA, and MDPPP were first identified in a zebrafish embryo (ZE) metabolism study followed by comparison to most abundant human ...
Simon K. Wellenberg +7 more
wiley +1 more source
Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies. [PDF]
, 2019 Variation in steroid hormone levels has wide implications for health and disease. The genes encoding the proteins involved in steroid disposition represent key determinants of interindividual variation in steroid levels and ultimately, their effects ...
Boerwinkle, Eric +13 more
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British Journal of Clinical Pharmacology, EarlyView.Background and Purpose Although opioids are central to end of life (EoL) care, tissue‐level opioid exposure remains poorly understood. The objective of this study was to characterize the relationship between prescription‐derived morphine equivalent daily dose (MEDD) and measured morphine concentrations across multiple organs.
Niamh Higgins +23 more
wiley +1 more source
Antioxidative Flavonol Glucuronides and Anti-HBsAg Flavonol from Rotala rotundifolia
Journal of Traditional and Complementary Medicine, 2011 Two new flavonol glucuronides, quercetin 3-O-β-d-2″-acetylglucuronide (1) and quercetin 3-O-β-d-2″-acetylglucuronide methyl ester (2), along with four known flavonoids (3-6) were isolated from the whole parts of Rotala rotundifolia.
Li-Jie Zhang +4 more
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