Abstracts submitted to the ‘EACR 2025 Congress: Innovative Cancer Science’, from 16–19 June 2025 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
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Functional expression of uridine diphospho glucuronosyltransferases in fission yeast [PDF]
Uridine diphospho (UDP) glucuronosyltransferases (UGTs) catalyze the transfer of a sugar moiety from UDP-sugar to endogenous or exogenous compounds. The water solubility of these substances is increased thereby and their excretion from the human body is ...
Buchheit, Daniela
core
BackgroundMaternal exposure to bisphenol A (BPA) during pregnancy is closely related to adverse growth and development conditions such as preterm birth and low birth weight, but the relevant mechanisms are still unclear.
Peili WANG+7 more
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Induction of Hepatic Microsomal UDP-Glucuronosyltransferase Activity in Nifedipine Treated Rats [PDF]
Young Sook Hong, Young-Sook Pae
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Irinotecan pathway genotype analysis to predict pharmacokinetics [PDF]
PURPOSE: The purpose was to explore the relationships between irinotecan disposition and allelic variants of genes coding for adenosine triphosphate binding cassette transporters and enzymes of putative relevance for irinotecan ...
Baker, S.D. (Sharyn)+7 more
core
Glucuronidation of benzidine and its metabolites by cDNA-expressed human UDP-glucuronosyltransferases and pH stability of glucuronides [PDF]
Marco Ciotti+5 more
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A Comparative Analysis of Michaelis-Menten, Hill, and Allosteric Models in Drug Metabolism
Background: Enzyme Kinetics it is a fundamental part of metabolic biochemistry because it helps to explore the mechanism of action and interaction of all substrates under the influence as well as environmental factors.
Ziyad K. Radeef
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Characterization of the UDP-glucuronosyltransferase isoenzyme expressed in rat ovary and its regulation by gonadotropins [PDF]
Luisa Becedas+2 more
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Glucuronidation of the environmental oestrogen bisphenol A by an isoform of UDP-glucuronosyltransferase, UGT2B1, in the rat liver [PDF]
Hiroshi Yokota+6 more
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