Inside the genome: understanding genetic influences on oxidative stress
Genetics is a key factor that governs the susceptibility to oxidative stress. In the body, oxidative burden is regulated by the balance between the prooxidant genes that orchestrate processes that produce oxidant species, while the antioxidant genes aid ...
Hari Krishnan Krishnamurthy +7 more
doaj +1 more source
This study elucidated the regulatory mechanisms of age-related meat flavor precursors in naturally grazed Sunit sheep of different ages (6, 18, and 30 months) by analyzing their metabolite and mRNA profiles.
Yajuan Huang +8 more
doaj +1 more source
Altered Functional Protein Networks in the Prefrontal Cortex and Amygdala of Victims of Suicide [PDF]
Czurkó, András +10 more
core +1 more source
Exploring key genes in NAFLD linked to glutamine metabolism: A comprehensive analysis combining multi-omics, machine learning and SHAP. [PDF]
Chen C, Liu W, Lan Y, Li F, Li X.
europepmc +1 more source
Mechanistic study of glutamine metabolic reprogramming driving non-small cell lung cancer progression via the FGF17-FGFR4 axis mediating epithelial-mesenchymal transition. [PDF]
Kong Q, Wang X, Ding W.
europepmc +1 more source
Hepatic zonation determines tumorigenic potential of mutant β-catenin. [PDF]
Raven A +33 more
europepmc +1 more source
HDAC inhibitor MS275 reprograms metabolism to induce differentiation and suppress proliferation in hepatocellular carcinoma. [PDF]
Li J +10 more
europepmc +1 more source
Impaired nitrogenous waste clearance promotes hepatocellular carcinoma. [PDF]
Han X +21 more
europepmc +1 more source
The Glutamine Metabolic Switch Influences the Response of Neonatal Intestinal Macrophages to Breast Milk. [PDF]
Han X +12 more
europepmc +1 more source
Objective / As dysfunction of glutamatergic neurotransmission is one of the plausible hypotheses for the pathogenesis of schizophrenia, genes involved in the glutamate neurotransmitter system are candidates for schizophrenia susceptibility. The aim of this study is to clarify the contribution of two genes encoding glutamate metabolic enzymes: the ...
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