Kemelut politik zaman kesultanan Melayu dalam Tuhfat al-Nafis [PDF]
, 2016 Kemelut politik yang berlaku dalam sesebuah kerajaan adalah antara punca utama tercetusnya kejatuhan sesebuah kerajaan tersebut. Permasalahan ini wujud, apabila terdapat pihak yang tidak lagi mengikut undang-undang negeri dan tidak lagi memperjuangkan ...
Amir Rullah Mohd Noor, +1 more
core +1 more source
Investigating the role of GLUL as a survival factor in cellular adaptation to glutamine depletion via targeted stable isotope resolved metabolomics [PDF]
Frontiers in Molecular Biosciences, 2022 Cellular glutamine synthesis is thought to be an important resistance factor in protecting cells from nutrient deprivation and may also contribute to drug resistance. The application of ‟targeted stable isotope resolved metabolomics” allowed to directly measure the activity of glutamine synthetase in the cell.
Șafak Bayram +10 more
openaire +3 more sources
Fungsi Sastra Lisan “Tanduk” Masyarakat Genaharjo Kabupaten Tuban Bagi Masyarakat Pendukungnya [PDF]
, 2016 This study aims to investigate the function of “tanduk” oral literature for its society. In this case, the people in question are society Genaharjo of Tuban district. Through the use of the theory of functions Alan Dundes and William R.
Suantoko, S. (Suantoko)
core +3 more sources
Leukemia Cells Resistant to Glutamine Deprivation Express Glutamine Synthetase Protein
Turkish Journal of Hematology, 2022 Objective: Low glutamine levels have been shown in tumor environments for several cancer subtypes. Therefore, it has been suggested that cancer cells rewire their metabolism to adopt low nutrient levels for survival and proliferation.
Burcu Yücel, Saniye Ada
doaj +1 more source
TP53-inducible Glycolysis and Apoptosis Regulator (TIGAR) Metabolically Reprograms Carcinoma and Stromal Cells in Breast Cancer. [PDF]
, 2016 A subgroup of breast cancers has several metabolic compartments. The mechanisms by which metabolic compartmentalization develop in tumors are poorly characterized. TP53 inducible glycolysis and apoptosis regulator (TIGAR) is a bisphosphatase that reduces
Bartrons, Ramon +15 more
core +2 more sources
Open Medicine, 2023 Acute myeloid leukemia (AML) is classified into favorable-risk, intermediate-risk, and poor-risk subtypes. This study aimed to compare the serum proteomic signatures of the three AML subtypes and identify prognostic biomarkers for AML. Serum samples from
Zhang Wei, Liu Bei, Wu Shiwen, Zhao Li
doaj +1 more source
Molecular Metabolism, 2022 Objective: Dicer is an enzyme that processes microRNAs (miRNAs) precursors into mature miRNAs, which have been implicated in various aspects of cancer progressions, such as clinical aggressiveness, prognosis, and survival outcomes.
Ji Min Park +10 more
doaj +1 more source
Variant rs10911021 that associates with coronary heart disease in type 2 diabetes, is associated with lower concentrations of circulating HDL cholesterol and large HDL particles but not with amino acids. [PDF]
, 2016 AIMS: An intergenic locus on chromosome 1 (lead SNP rs10911021) was previously associated with coronary heart disease (CHD) in type 2 diabetes (T2D). Using data from the UCLEB consortium we investigated the relationship between rs10911021 and CHD in T2D,
Ala-Korpela, Mika +19 more
core +8 more sources
Neurobiology of Disease, 2006 Mild cognitive impairment (MCI) is generally referred to the transitional zone between normal cognitive function and early dementia or clinically probable Alzheimer's disease (AD).
D. Allan Butterfield +6 more
doaj +1 more source
Gene transfer engineering for astrocyte-specific silencing in the CNS. [PDF]
, 2015 Cell-type-specific gene silencing is critical to understand cell functions in normal and pathological conditions, in particular in the brain where strong cellular heterogeneity exists.
Delzor, A. +6 more
core +1 more source