Results 111 to 120 of about 41,570 (221)

Comparative analysis of two genomic regions among four strains of Buchnera aphidicola, primary endosymbiont of aphids.

open access: yes, 2004
Preliminary analysis of two selected genomic regions of Buchnera aphidicola BCc, the primary endosymbiont of the cedar aphid Cinara cedri, has revealed a number of interesting features when compared with the corresponding homologous regions of the three ...
Gil, Rosario   +3 more
core   +1 more source

Cleavage of the apoptosis inhibitor DIAP1 by the apical caspase DRONC in both normal and apoptotic drosophila cells [PDF]

open access: yes, 2005
In Drosophila S2 cells, the apical caspase DRONC undergoes a low level of spontaneous autoprocessing. Unintended apoptosis is prevented by the inhibitor of apoptosis DIAP1, which targets the processed form of DRONC for degradation through its E3 ...
Clem, Rollie J.   +2 more
core   +1 more source

Chrysin Mitigates Acetamiprid‐Induced Testicular Injury in Mice via Suppression of Endoplasmic Reticulum Stress and Inflammation

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Acetamiprid (ACP) is a neonicotinoid pesticide that is extensively utilized for the management of insect populations, but its toxic effects on the male reproductive system have become a source of concern. Chrysin (CHR) is a natural flavone found in many plants and bee products, including honey and propolis.
Selim Demir   +7 more
wiley   +1 more source

Implication of the glutamate-cystine antiporter xCT in schizophrenia cases linked to impaired GSH synthesis. [PDF]

open access: yes, 2017
xCT is the specific chain of the cystine/glutamate antiporter, which is widely reported to support anti-oxidant defenses in vivo. xCT is therefore at the crossroads between two processes that are involved in schizophrenia: oxidative stress and ...
Baumann, P.S.   +5 more
core   +3 more sources

Comparative Analysis of Heat Exposure‐Induced Molecular Changes in Two Turtle Species with Contrasting Thermal Adaptations

open access: yesIntegrative Zoology, EarlyView.
Protein processing in the endoplasmic reticulum is highlighted in response to heat stress in Platysternon megacephalum. Under heat stress, the up‐regulation of genes such as CHOP in protein processing in the endoplasmic reticulum pathway, along with the suppression of energy and lipid metabolism and the up‐regulation of JARID2 expression, leads to ...
Jian Hong   +7 more
wiley   +1 more source

Expression, purification and characterization of glutamate cysteine ligase from Saccharomyces cerevisiae

open access: yesThe FASEB Journal, 2008
Glutathione is a critical cellular reductant and its homeostasis is required for maintenance of intracellular redox balance. glutamate‐cysteine ligase (GCL) catalyses the ATP‐dependent peptide bond formation between gamma‐carboxylate of glutamate and cysteine, the first step of glutathione biosynthesis.
Ekaterina Biterova   +2 more
openaire   +1 more source

Plasmids in the aphid endosymbiont Buchnera aphidicola with the smallest genomes. A puzzling evolutionary story.

open access: yes, 2006
Buchnera aphidicola, the primary endosymbiont of aphids, has undergone important genomic and biochemical changes as an adaptation to intracellular life.
Gil, Rosario   +4 more
core   +1 more source

Moderate increase of MET in hepatocytes protects against cholestatic liver injury by promoting an effective antioxidant response

open access: yesThe FEBS Journal, EarlyView.
Moderate overexpression of wild‐type Met in hepatocytes (Alb‐R26Met mouse model) boosts a strong antioxidant response dependent on the glutathione system while impairing TGF‐β signaling in the liver. This leads to improved liver regeneration and protects against DDC‐induced injury, a model for cholestatic disease sharing features with primary ...
Carlos González‐Corralejo   +16 more
wiley   +1 more source

Age-dependent regulation of antioxidant genes by p38α MAPK in the liver

open access: yesRedox Biology, 2018
p38α is a redox sensitive MAPK activated by pro-inflammatory cytokines and environmental, genotoxic and endoplasmic reticulum stresses. The aim of this work was to assess whether p38α controls the antioxidant defense in the liver, and if so, to elucidate
Salvador Pérez   +6 more
doaj   +1 more source

Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]

open access: yes, 2008
Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama   +4 more
core   +1 more source

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