Results 11 to 20 of about 227,873 (271)

Transaminations catalysed by brain glutamate decarboxylase [PDF]

Biochemical Journal, 1985
In addition to normal decarboxylation of glutamate to 4-aminobutyrate, glutamate decarboxylase from pig brain was shown to catalyse decarboxylation-dependent transamination of L-glutamate and direct transamination of 4-aminobutyrate with pyridoxal 5′-phosphate to yield succinic semialdehyde and pyridoxamine 5′-phosphate in a 1:1 stoichiometric ratio ...
T G, Porter, D C, Spink, S B, Martin, D L, Martin   +3 more
openaire   +4 more sources

Enhanced production of gamma-aminobutyrate (GABA) in recombinant Corynebacterium glutamicum by expressing glutamate decarboxylase active in expanded pH range [PDF]

Microbial Cell Factories, 2015
BackgroundGamma-aminobutylate (GABA) is an important chemical in pharmacetucal field and chemical industry. GABA has mostly been produced in lactic acid bacteria by adding L-glutamate to the culture medium since L-glutamate can be converted into GABA by ...
Jae Woong Choi, S. Yim, S. H. Lee, T. Kang, Si Jae Park, K. Jeong   +5 more
semanticscholar   +2 more sources

A randomized trial of oral gamma aminobutyric acid (GABA) or the combination of GABA with glutamic acid decarboxylase (GAD) on pancreatic islet endocrine function in children with newly diagnosed type 1 diabetes

Nature Communications, 2022
Based on preclinical studies, gamma aminobutyric acid (GABA) and immunization for the enzyme that produces GABA glutamate decarboxylase (GAD) could be a potential therapy for type 1 diabetes.
Alexandra Martin, Gail J. Mick, Heather M. Choat, Alison A. Lunsford, Hubert M. Tse, Gerald G. McGwin, Kenneth L. McCormick   +6 more
doaj   +2 more sources

An H-NS Family Protein, Sfh, Regulates Acid Resistance by Inhibition of Glutamate Decarboxylase Expression in Shigella flexneri 2457T [PDF]

Frontiers in Microbiology, 2017
The glutamate-dependent acid-resistance system is the most effective acid tolerance pathway in Shigella, allowing survival in extremely acidic environments. However, the regulation of this system in Shigella remains elusive.
Chang Niu, Chang Niu, Dongshu Wang, Xiaoqing Liu, Hongsheng Liu, Xiankai Liu, Erling Feng, Chao Pan, Ruifeng Wang, Wei Xiao, Xingming Liu, Xinrui Liu, Li Zhu, Hengliang Wang   +13 more
doaj   +2 more sources

A plasmid-borne gadRCB operon contributes to acid tolerance in Lactiplantibacillus plantarum ZR79 [PDF]

Applied Microbiology and Biotechnology
The glutamate decarboxylase (GAD) system catalyzed the conversion of L-glutamate to gamma-aminobutyric acid (GABA) in a proton-consuming reaction, which played a critical role to maintain intracellular pH homeostasis.
Chengfei Fan, Zeyu Cao, Xinfeng Liu, Yan Hao, Zhengyuan Zhai, Yanling Hao   +5 more
doaj   +2 more sources

Effect of different salt concentrations on the gamma-aminobutyric-acid content and glutamate decarboxylase activity in germinated sorghum (Sorghum bicolor L. Moench) grain. [PDF]

Food Sci Nutr, 2022
Elbaloula MF, Hassan AB.
europepmc   +2 more sources

Glutamate decarboxylase 67 contributes to compensatory insulin secretion in aged pancreatic islets. [PDF]

Islets, 2019
Cho JH, Lee KM, Lee YI, Nam HG, Jeon WB.
europepmc   +3 more sources

Molecular evolution and population genetics of glutamate decarboxylase acid resistance pathway in lactic acid bacteria. [PDF]

Front Genet, 2023
Sezgin E, Tekin B.
europepmc   +2 more sources

Biochemical and Enzymatic Analyses to Understand the Accumulation of γ-Aminobutyric Acid in Wheat Grown under Flooding Stress

Oxygen, 2023
Flooding induces low-oxygen stress, which reduces plant growth. The activity of the γ-aminobutyric acid (GABA) shunt is crucial for plant stress adaptation, in which it acts by changing cytosolic pH, limiting reactive oxygen species production ...
Setsuko Komatsu, Natsuru Nishiyama, Azzahrah Diniyah   +2 more
doaj   +1 more source

Glutamic Acid Decarboxylase in Legumes [PDF]

Nature, 1956
Since the pioneer researches of Okuniki1,2 and Schales and his associates3–5 on glutamic acid decarboxylase, rather scanty data have been made available on amino-acid decarboxylases of plants. Most of the work deals with glutamic acid decarboxylase of higher plants; so it was thought of interest to study the enzyme system in the case of dry seeds of ...
L, KULKARNI, K, SOHONIE
openaire   +2 more sources