Results 21 to 30 of about 228,854 (227)

Chronic noise stress-induced alterations of glutamate and gamma-aminobutyric acid and their metabolism in the rat brain

open access: yesNoise and Health, 2014
Chronic stress induces neurochemical changes that include neurotransmitter imbalance in the brain. Noise is an environmental factor inducing stress. Chronic noise stress affects monoamine neurotransmitter systems in the central nervous system. The effect
Amajad Iqbal Kazi, Anna Oommen
doaj   +1 more source

A Novel, Easy Assay Method for Human Cysteine Sulfinic Acid Decarboxylase

open access: yesLife, 2021
Cysteine sulfinic acid decarboxylase catalyzes the last step of taurine biosynthesis in mammals, and belongs to the fold type I superfamily of pyridoxal-5′-phosphate (PLP)-dependent enzymes.
Angela Tramonti   +5 more
doaj   +1 more source

The Role of Elastase Antibodies, Circulating Autoantibodies to Glutamate Decarboxylase and Islet Cells Antigens in Chronic Pancreatitis

open access: yesGastroenterologìa, 2014
The article presents an analysis of the occurrence of elastase antibodies, circulating autoantibodies to glutamate decarboxylase and islet cells antigens in different forms of chronic pancreatitis.
V.Yu. Koval
doaj   +1 more source

Safety and efficacy of autoantigen‐specific therapy with 2 doses of alum‐formulated glutamate decarboxylase in children with multiple islet autoantibodies and risk for type 1 diabetes: A randomized clinical trial

open access: yesPediatric Diabetes, 2018
Treatments have failed to delay or stop the autoimmune process, preceding onset of type 1 diabetes. We investigated if autoantigen‐specific treatment with alum‐formulated glutamate decarboxylase (GAD‐Alum) was safe and affected progression to type 1 ...
H. Elding Larsson   +4 more
semanticscholar   +1 more source

Extraction and Quantification of GABA and Glutamate from Cyanobacterium Synechocystis sp. PCC 6803

open access: yesBio-Protocol, 2016
GABA (γ-amino butyric acid) is a biologically active four carbon non-protein amino acid found in prokaryotes and eukaryotes. Glutamate is a five carbon α-amino acid which can be converted to GABA catalyzed by the enzyme glutamate decarboxylase.
Simab Kanwal, Aran Incharoensakdi
doaj   +1 more source

The effect of sodium thiopental as a GABA mimetic drug in neonatal period on expression of GAD65 and GAD67 genes in hippocampus of newborn and adult male rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2017
Objective(s): Development of the nervous system in human and most animals is continued after the birth. Critical role of this period in generation and specialization of the neuronal circuits is confirmed in numerous studies.
Masoud Naseri, Abbas Parham, Ali Moghimi
doaj   +1 more source

Enhance Production of γ-Aminobutyric Acid (GABA) and Improve the Function of Fermented Quinoa by Cold Stress

open access: yesFoods, 2022
Quinoa is an excellent source of γ-aminobutyric acid (GABA), which is a natural four-carbon non-protein amino acid with great health benefits. In this study, the quinoa was treated by cold stress before fermentation with Lactobacillus plantarum to ...
Yucui Zhang   +4 more
doaj   +1 more source

Elevated histone H3 acetylation is associated with genes involved in T lymphocyte activation and glutamate decarboxylase antibody production in patients with type 1 diabetes

open access: yesJournal of Diabetes Investigation, 2019
Aims/Introduction Genetic and epigenetic mechanisms have been implicated in the pathogenesis of type 1 diabetes, and histone acetylation is an epigenetic modification pattern that activates gene transcription.
Yanfei Wang   +7 more
doaj   +1 more source

Modulation of gene expression in guinea pig paraflocculus after induction of hearing loss [v2; ref status: indexed, http://f1000r.es/3c5]

open access: yesF1000Research, 2014
Hearing loss often results in plastic changes in the central auditory pathways, which may be involved in the generation of tinnitus, a phantom auditory sensation.
Wilhelmina H. A. M. Mulders   +3 more
doaj   +1 more source

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