Results 101 to 110 of about 249,745 (307)

Investigating glutamate receptor-like gene co-expression in Arabidopsis thaliana [PDF]

, 2008
There is increasing evidence of the important roles of glutamate receptors (GLRs) in plant development and in adaptation to stresses. However, the studies of these putative ion channels, both in planta and in Xenopus oocytes, may have been limited by our
P. RICHARDSON, Miller, A. J., Liu, L., Leigh, R., A. J. MILLER, Essah, P., S. J. ROY, M. GILLIHAM, Leigh, R. A., Roy, S., Roy, S. J., Tester, M., Liu, L-H., Miller, A., J. M. DAVIES, Davenport, R. J., Essah, P. A., M. TESTER, Gilliham, M., Davies, J. M., P. A. ESSAH, L.‐H. LIU, B. BERGER, Berger, B., R. J. DAVENPORT, Skynner, M., Richardson, P., Davenport, R., M. J. SKYNNER, R. A. LEIGH, Cheffings, C., C. CHEFFINGS, Davies, J., Skynner, M. J.   +33 more
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A Chemical Framework for Engineering Extracellular Vesicles’ Biointerface to Advance Precision Therapeutics

Advanced Materials, EarlyView.
Extracellular vesicles (EVs) are cell‐derived nanoparticles that mediate intercellular communication through their dynamic biointerfaces. Owing to their intrinsic biological functions, EVs have emerged as promising platforms for biomedical applications.
Leila Pourtalebi Jahromi, Felix Geng, Jan‐Noël Frenzke, Gregor Fuhrmann   +3 more
wiley   +1 more source

Intrinsically Stretchable Piezoelectric Nanocomposites for Artificial Ultrasonic Sensory Synapse

Advanced Materials, EarlyView.
Applying ultrasonic stimulations to a soft‐stretchable underwater piezoelectric sensor based on the soft‐stretchable nanocomposite from the thermal cross‐linking between the ─C─F group of P(VDF‐TrFE) and the ─NH2 group of (PEG‐diamine) with incorporating amine‐terminated BTO@APTES nanofillers on the soft PDMS substrates generated high piezoelectric ...
Trung Dieu Do, Tran Quang Trung, Priyanuj Bhuyan, Minh Chien Nguyen, Que Thi Nguyen, Namjun Jo, Yeonsu Kim, Thanh Duy Cam Ha, Myung‐Gil Kim, Sungjune Park, Woo Jong Yu, Nae‐Eung Lee   +11 more
wiley   +1 more source

Plasticity of GABAB receptor-mediated heterosynaptic interactions at mossy fibers after status epilepticus [PDF]

, 2003
Several neurotransmitters, including GABA acting at presynaptic GABAB receptors, modulate glutamate release at synapses between hippocampal mossy fibers and CA3 pyramidal neurons.
Bowery, N.G., Walker, M.C., Chandler, K.E., Chandler, K. E., Princivalle, A.P., Walker, M. C., Princivalle, A. P., Fabian-Fine, R., Bowery, N. G., Kullmann, D. M., Kullmann, D.M.   +10 more
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Glutamate Receptor Agonists and Glutamate Transporter Antagonists Regulate Differentiation of Osteoblast Lineage Cells [PDF]

, 2016
Development and function of osteoblast lineage cells are regulated by a complex microenvironment consisting of the bone extracellular matrix, cells, systemic hormones and cytokines, autocrine and paracrine factors, and mechanical load.
Hofstetter, Wilhelm, Wetterwald, Antoinette, Dolder, Silvia, Siegrist, Mark, Xie, Wenjie   +4 more
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Control of cleft glutamate concentration and glutamate spill-out by perisynaptic glia: uptake and diffusion barriers.

PLoS ONE, 2013
Most glutamatergic synapses in the mammalian central nervous system are covered by thin astroglial processes that exert a dual action on synaptically released glutamate: they form physical barriers that oppose diffusion and they carry specific ...
Jean-Pierre Kessler
doaj   +1 more source

CPP–PEG‐Guided Surface Engineering of Mitochondria Enables Efficient Cellular Uptake and Respiratory Modulation

Advanced Materials Interfaces, EarlyView.
PEG‐guided mitochondrial surface engineering supports structural stabilization and controlled presentation of cell‐penetrating peptides. CPP–PEG‐modified mitochondria exhibit enhanced cellular uptake and uptake‐associated respiratory modulation, providing a proof‐of‐concept framework for modular organelle engineering and future bioenergetic modulation ...
Masahiro Shiraishi, Yukari Muramatsu, Akihiro Nakaya, Yuji Maruo, Rick C. Tsai, Masashi Suganuma, Hisashi Ohta, Atsuhito Takeda, Hideyoshi Harashima, Yuma Yamada   +9 more
wiley   +1 more source

Hypoxic injury of isolated axons is independent of ionotropic glutamate receptors

Neurobiology of Disease, 2007
Axonal injury in white matter is an important consequence of many acute neurological diseases including ischemia. A role for glutamate-mediated excitotoxicity is suggested by observations from in vitro and in situ models that AMPA/kainate blockers can ...
Suzanne M. Underhill, Mark P. Goldberg
doaj   +1 more source

Phosphorylation‐Facilitated CKB Lactylation At K11 By GCN5 Enhances Creatine Kinase Activity and Mitigates Neuronal Damage After Cerebral Ischemia‐Reperfusion

Advanced Science, EarlyView.
This study uncovers hierarchical coordination between K11 lactylation and S199 phosphorylation of CKB in cerebral ischemia‐reperfusion injury. Such dual modifications potentiate CKB enzymatic function, remodel energy metabolism, alleviate oxidative stress and neuronal damage, and represent a viable therapeutic target for stroke treatment.
Chao Duan, Ruolin Zhang, Shihui Ding, Ying Feng, Tao Shen, Ziwei Wang, Wendai Bao, Ke Shui, Jun Qin, Jun Chen, Min Zhang, Zijing Ren, Dongmei Zhao, Xingrong Guo, Zhibing Ai, Xin Yang, Peiyang Zhou, Zhiqiang Dong   +17 more
wiley   +1 more source

Allosteric modulators of metabotropic glutamate receptors: from virtual screening to experimental validation [PDF]

, 2007
The goal of this thesis was to gain further insight into the binding behavior of ligands in the heptahelical domain (HD) of group I metabotropic glutamate receptors (mGluRs).
Noeske, Tobias
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