Results 231 to 240 of about 2,577,793 (359)

Structural conservation of ion conduction pathways in K channels and glutamate receptors.

open access: green, 1995
Michael W. Wood   +2 more
openalex   +1 more source

Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder

open access: yesNature Genetics, 2011
J. Elia   +70 more
semanticscholar   +1 more source

Phenylalanine‐Based DNA‐Encoded Chemical Libraries for the Discovery of Potent and Selective Small Organic Ligands Against Markers of Cancer and Immune Cells

open access: yesAdvanced Science, EarlyView.
FM‐DEL1 and FM‐DEL2 are constructed by installing one or two sets of building blocks on a phenylalanine central scaffold. FM‐DELs are screened against markers of prostate, and renal cell carcinoma, and against an immunological target expressed on the surface of natural killer cells.
Francesca Migliorini   +12 more
wiley   +1 more source

Effectiveness of positive allosteric modulators of metabotropic glutamate receptor 2/3 (mGluR2/3) in animal models of schizophrenia. [PDF]

open access: yesTransl Psychiatry
Olivares-Berjaga D   +6 more
europepmc   +1 more source

Contribution of Prostaglandin E2‐Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood–Brain Barrier Crossing Celecoxib Derivative

open access: yesAdvanced Science, EarlyView.
Glioblastoma (GBM) is an aggressive brain cancer that often recurs and resists chemotherapy. This study found that a chemical called PGE2 causes surrounding brain cells (neurons) to become over‐excited, which makes GBM cells resistant to treatment. Researchers developed a new drug, “Compound 11,” which can cross into the brain and effectively block ...
Chih‐Jie Shen   +14 more
wiley   +1 more source

Role of Glutamate Receptor-Mediated Excitotoxicity in Bilirubin-Induced Brain Injury in the Gunn Rat Model

open access: hybrid, 1998
John W. McDonald   +3 more
openalex   +1 more source

Antibodies to metabotropic glutamate receptor 5 in the Ophelia syndrome

open access: yesNeurology, 2011
E. Lancaster   +15 more
semanticscholar   +1 more source

Genomic Insights into the Origin, High Fecundity and Environmental Adaptation of Hu Sheep

open access: yesAdvanced Science, EarlyView.
The Hu sheep diverged from the Small‐tailed Han sheep ≈1330 years ago, and subsequently migrated from northern to warm and humid southern regions. The genes BMPR1B, UNC5C, and GRID2 play a synergistic role in the superior reproductive traits of Hu sheep.
Zexuan Liu   +12 more
wiley   +1 more source

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