Results 211 to 220 of about 2,596,775 (326)

Akt regulates glutamate receptor trafficking and postsynaptic membrane elaboration at the Drosophila neuromuscular junction [PDF]

, 2013
Hyun‐Gwan Lee, Na Zhao, Bridget Kelly Campion, Michelle M. Nguyen, Scott B. Selleck   +4 more
openalex   +1 more source

Antibody‐Empowered Nanomedicine for Precise Biomedical Applications

Advanced Science, EarlyView.
This review explores strategies for functionalizing nanoparticles with antibodies to construct antibody‐empowered nanomedicine. It discusses the classification of these nanomedicines based on antibody structure, with a specific focus on their biomedical applications in diagnostics, bioimaging, and therapeutics for various diseases.
Chen Chen, Xinglin Chen, Zhenhao Gao, Meng Sun, Yaozong Yu, Fang Lv, Qiujun Wang, Jinfeng Zhang   +7 more
wiley   +1 more source

Synaptic Plasticity Linked to Ionotropic Glutamate Receptors After Nicotine Exposure. [PDF]

Curr Neuropharmacol
Kazmi A, Choe ES.
europepmc   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

Advanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling, Aïda Yakhlef Sanchez, Nicolas Thelen, Müge Senarisoy, Maria Hogg, Steven Condamine, Andrea Lelli, Emilia Wysocka, Pranav Patni, Sandrine Vitry, Kerem Yasin Yildizhan, Sébastien Le Gal, Sylvie Nouaille, Michael R. Bowl, Marc Thiry, Didier Dulon, Sedigheh Delmaghani, Aziz El‐Amraoui   +17 more
wiley   +1 more source

The SNARE protein Ykt6 drives insertion of the GluA1 and GluA2 glutamate receptors at synaptic spines during long-term potentiation. [PDF]

J Biol Chem
Takahashi M, Raman M, Caraveo G.
europepmc   +1 more source

Ubiquitination‐Driven Reprogramming of Proteostasis in Metastasis

Advanced Science, EarlyView.
The DCAF12–TRiC/CCT axis is a key regulator of metastasis in cancer. By reprogramming proteostasis to ensure efficient protein folding, it drives progression through a dual mechanism: enhancing cancer cell motility and invasiveness while concurrently activating pro‐growth and survival pathways.
Dongping Wei, Jiayan Chen, Yaping Xu
wiley   +1 more source

Photoswitching endogenous glutamate receptors in neural ensembles and single synapses in vivo.

Brain Stimul
Garrido-Charles A, Bosch M, Lee H, Rovira X, Pittolo S, Llobet A, Wong HH, Trapero A, Matera C, Papotto C, Serra C, Llebaria A, Soriano E, Sanchez-Vives MV, Holt CE, Gorostiza P.   +15 more
europepmc   +1 more source

Ionotropic receptors (IRs): chemosensory ionotropic glutamate receptors in Drosophila and beyond.

Insect Biochemistry and Molecular Biology, 2013
R. Rytz, Vincent Croset, R. Benton
semanticscholar   +1 more source

Effects of Synaptic Frequency and Glutamate Transport on NMDA Receptor Activity at the Shaffer-CA1 Synapse

, 2015
Genevieve E. Lind, Weinan Sun, Katie M. Hoffman, Michael Kavanaugh   +3 more
openalex   +1 more source

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

Advanced Science, EarlyView.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély, István Narozsny, Levente Szarka, Daniel V. Veres, Peter Csermely, Dávid Keresztes   +5 more
wiley   +1 more source