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The Role of Glutamate Transporters in Glutamate Homeostasis in the Brain
Journal of Experimental Biology, 1997ABSTRACT Glutamate transporters in neurones and glia, four of which have been cloned from mammals, play a crucial role in controlling the extracellular glutamate concentration in the brain. In normal conditions, they remove glutamate from the extracellular space and thereby help to terminate glutamatergic synaptic transmission and to ...
M, Takahashi +5 more
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Oxidative deamination of glutamate and transdeamination through glutamate
Archives of Biochemistry and Biophysics, 1966Abstract Rat liver mitochondria are able to produce ammonia from glutamate at a steady rate under the conditions described. A system generating ADP from ATP is necessary for the continual deamination of glutamate. Maximum stimulation is reached with a hexokinase-glucose system in the presence of 0.2 m m ATP.
F J, Hird, M A, Marginson
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Headache Currents, 2004
The NMDA Receptor Antagonist MK‐801 Reduces Fos‐like Immunoreactivity Within the Trigeminocervical Complex Following Superior Sagittal Sinus Stimulation in the Cat Expression of Fos protein is an indicator of neuronal perturbation and is readily observed in the caudal medulla and the spinal cord following trigeminovascular nociceptive
BROMAN J. +4 more
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The NMDA Receptor Antagonist MK‐801 Reduces Fos‐like Immunoreactivity Within the Trigeminocervical Complex Following Superior Sagittal Sinus Stimulation in the Cat Expression of Fos protein is an indicator of neuronal perturbation and is readily observed in the caudal medulla and the spinal cord following trigeminovascular nociceptive
BROMAN J. +4 more
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Glutamate receptors and new glutamate agonists
Trends in Pharmacological Sciences, 1983Abstract A variety of naturally occurring and synthetic analogues of the putative excitatory amino acid neurotransmittersl-glutamic acid (l-GLU) andl-aspartec acid (l-ASP) are powerful neuroexcitatory and neurotoxic agents. These effects appear to be mediated primarily by the central receptors normally operated byl-GLU and/orl-ASP.
Povl Krogsgaard-Larsen, Tage Honore´
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Progress in Neurobiology, 2001
Brain tissue has a remarkable ability to accumulate glutamate. This ability is due to glutamate transporter proteins present in the plasma membranes of both glial cells and neurons. The transporter proteins represent the only (significant) mechanism for removal of glutamate from the extracellular fluid and their importance for the long-term maintenance
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Brain tissue has a remarkable ability to accumulate glutamate. This ability is due to glutamate transporter proteins present in the plasma membranes of both glial cells and neurons. The transporter proteins represent the only (significant) mechanism for removal of glutamate from the extracellular fluid and their importance for the long-term maintenance
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Glutamate and Glutamate Receptors in the Vertebrate Retina
2023Book chapter published in: Kolb, H., Fernandez, E., Nelson, R., Webvision: The Organization of the Retina and Visual System [Internet].
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2012
Orexin neurons are localized in the lateral hypothalamus and regulate many functions including sleep-wake states. Substantial number of neurotransmitters and neuromodulators has been proposed to influence orexinergic system. Glutamate, as the major excitatory amino acid neurotransmitter in the hypothalamus, was shown to mediate orexin neurons in the ...
Minbay, Zehra +2 more
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Orexin neurons are localized in the lateral hypothalamus and regulate many functions including sleep-wake states. Substantial number of neurotransmitters and neuromodulators has been proposed to influence orexinergic system. Glutamate, as the major excitatory amino acid neurotransmitter in the hypothalamus, was shown to mediate orexin neurons in the ...
Minbay, Zehra +2 more
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Glutamate synthase and the synthesis of glutamate in plants
Plant Physiology and Biochemistry, 2003The discovery of glutamate synthases (E.C. 1.4.1.13 and E.C. 1.4.7.1) caused a major re-assessment of the way in which ammonium is assimilated in bacteria and higher plants. The history of that discovery is reviewed and considered in the light of recent developments in the biochemistry and genetics of the higher plant ferredoxin- and NADH-dependent ...
Lea, Peter John, Miflin, Ben J.
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