Results 31 to 40 of about 226,163 (382)
Liability of a Surgeon for the Extension of an Authorized Operation [PDF]
, 1956 Polyunsaturated fatty acids modulate the voltage dependence of several voltage-gated ion channels, thereby being potent modifiers of cellular excitability.
Billman +43 more
core +2 more sources
QM/MM study of the stereospecific proton exchange of glutathiohydroxyacetone by glyoxalase I
Results in Chemistry, 2019 We have performed quantum mechanics (QM), molecular mechanics (MM) and hybrid QM/MM calculations to study the stereospecific proton exchange of glutathiohydroxyacetone (HOC-SG) by glyoxalase I (GlxI). We did the QM/MM calculations with a large QM system (
Sonia Jafari, Ulf Ryde, Mehdi Irani
doaj +1 more source
Glutamate Taste: Discrimination between the Tastes of Glutamate Agonists and Monosodium Glutamate in Rats [PDF]
Chemical Senses, 2004 Taste aversion studies have demonstrated that rats conditioned to avoid monosodium glutamate (MSG) with amiloride added to reduce the intensity of the sodium component of MSG taste, generalize this aversion to aspartic acid and to L-AP4, but not to ionotropic glutamate receptor agonists.
Delay, Eugene R. +3 more
openaire +3 more sources
Plants, 2022 Coding sequences of the CLC family genes SaCLCd, SaCLCf, and SaCLCg, the putative orthologs of Arabidopsis thaliana AtCLCd, AtCLCf, and AtCLCg genes, were cloned from the euhalophyte Suaeda altissima (L.) Pall.
Olga I. Nedelyaeva +3 more
doaj +1 more source
Diversity of Fe2+ entry and oxidation in ferritins [PDF]
, 2017 The essential metal iron presents two major problems for life: it is potentially highly toxic due to its redox activity, and its extremely low solubility in aqueous solution in the presence of O2 can make it hard to acquire and store safely.
Bradley, Justin M. +2 more
core +1 more source
Transient expression in Nicotiana benthamiana for rapid functional analysis of genes involved in non-photochemical quenching and carotenoid biosynthesis. [PDF]
, 2016 Plants must switch rapidly between light harvesting and photoprotection in response to environmental fluctuations in light intensity. This switch can lead to losses in absorbed energy usage, as photoprotective energy dissipation mechanisms can take ...
Erickson, Erika +3 more
core +1 more source
MoleculesThe reaction of arylidene-α-amino esters with electrophilic alkenes to yield Michael-type addition compounds is optimized using several phosphines as organocatalysts. The transformation is very complicated due to the generation of several final compounds,
Lesly V. Rodríguez-Flórez +6 more
doaj +1 more source
Synthesis of N -(4-propargylaminobenzoyl)-L-glutamates
Pteridines, 1994 To facilitate the rather labour consuming synthesis of antifolate γ-oligo-L-glutamates including those with the propargyl group at position N10 , two synthons possessing this group, α-t-butyl γ-methyl N-(4-propargylaminobenzoyl)- L-glutamate (1) and a-t ...
Kempny Michal +2 more
doaj +1 more source
Frontiers in Molecular Neuroscience, 2022 The natriuretic peptide receptors NPR1 and NPR2, also known as guanylyl cyclase A and guanylyl cyclase B, have critical functions in many signaling pathways, but much remains unknown about their localization and function in vivo. To facilitate studies of
Jeremy R. Egbert +13 more
doaj +1 more source
Energetics of discrete selectivity bands and mutation-induced transitions in the calcium-sodium ion channels family [PDF]
, 2013 We use Brownian dynamics (BD) simulations to study the ionic conduction and valence selectivity of a generic electrostatic model of a biological ion channel as functions of the fixed charge Qf at its selectivity filter.
Eisenberg, Robert S. +4 more
core +2 more sources