Results 31 to 40 of about 221,194 (241)

Obesity as a Limiting Factor for Remote Ischemic Postconditioning-Mediated Neuroprotection after Stroke

Journal of Obesity & Metabolic Syndrome
Background : Remote ischemic postconditioning (RIPostC) may protect the brain from ischemia/reperfusion (I/R) injury. The association between RIPostC and obesity has not yet been extensively studied.
Klaudia Kotorová, Jana Končeková, Miroslav Gottlieb, Martin Bona, Petra Bonová   +4 more
doaj   +1 more source

Beyond Sulfate-Free Personal Cleansing Technology

Cosmetics
There is a strong global demand for sulfate-free personal cleansing products. The objective of sulfate-free personal cleansing technology should not be aimed solely at the absence of “sulfate” wording in the list of ingredients, but on the true benefits ...
Evelyn Su, Stephen Herman
doaj   +1 more source

Expression and purification of recombinant vesicular glutamate transporter VGLUT1 using PC12 cells and High Five insect cells

Biological Procedures Online, 2004
In synaptic vesicles, the estimated concentration of the excitatory amino acid glutamate is 100-150 mM. It was recently discovered that VGLUT1, previously characterized as an inorganic phosphate transporter (BNPI) with 9-11 predicted transmembrane ...
Andersen Søren S.L.
doaj   +1 more source

Replacement of all alpha-domain lysines with glutamates reduces metallothionein detoxification function.

Biochemical and Biophysical Research Communications - BBRC, 1994
Mammalian metallothioneins (MTs) possess eight highly conserved lysine residues, including three in each of two metal binding domains. We used site-directed mutagenesis to replace these intradomain lysines in Chinese hamster ovary MT2 with glutamic acid ...
C. Cody, P. C. Huang
semanticscholar   +1 more source

Cortical glutamate in migraine [PDF]

Brain, 2017
Cortical hyperexcitability due to enhanced glutamatergic activity has been implicated in migraine pathophysiology but direct evidence is lacking. Here we assessed glutamate levels and intracellular mobility of glutamate in the visual cortex of migraineurs in-between attacks.
Mark C. Kruit, Michel D. Ferrari, Hermien E. Kan, Jannie P. Wijnen, Jannie P. Wijnen, Itamar Ronen, Andrew G. Webb, Gisela M. Terwindt, Ronald Zielman, Gerrit L J Onderwater   +9 more
openaire   +5 more sources

Glutamate Receptor [PDF]

, 2016
[No abstract]
openaire   +2 more sources

Long-term NMDAR antagonism correlates reduced astrocytic glutamate uptake with anxiety-like phenotype

Frontiers in Cellular Neuroscience, 2015
The role of glutamate N-methyl-D-Aspartate receptor (NMDAR) hypofunction has been extensively studied in schizophrenia; however, less is known about its role in anxiety disorders.
Eduardo R Zimmer, Vitor R Torrez, Eduardo eKalinine, Eduardo eKalinine, Marina C Augustin, Kamila C Zenki, Roberto Farina Almeida, Gisele eHansel, Alexandre P Muller, Diogo O Souza, Rodrigo eMachado-Vieira, Rodrigo eMachado-Vieira, Luis V Portela   +12 more
doaj   +1 more source

Cofactor Tail Length Modulates Catalysis of Bacterial F420-Dependent Oxidoreductases

Frontiers in Microbiology, 2017
F420 is a microbial cofactor that mediates a wide range of physiologically important and industrially relevant redox reactions, including in methanogenesis and tetracycline biosynthesis.
Blair Ney, Blair Ney, Carlo R. Carere, Richard Sparling, Richard Sparling, Thanavit Jirapanjawat, Matthew B. Stott, Colin J. Jackson, John G. Oakeshott, Andrew C. Warden, Chris Greening, Chris Greening   +11 more
doaj   +1 more source

Metabotropic Glutamate Receptors Inhibit Microglial Glutamate Release [PDF]

ASN Neuro, 2012
Pro-inflammatory stimuli evoke an export of glutamate from microglia that is sufficient to contribute to excitotoxicity in neighbouring neurons. Since microglia also express various glutamate receptors themselves, we were interested in the potential feedback of glutamate on this system. Several agonists of mGluRs (metabotropic glutamate receptors) were
Steven W. Barger, Stephen M McMullan, Bounleut Phanavanh, Gary Guo Li   +3 more
openaire   +4 more sources

Biochemical characterization of mutants in the active site residues of the β-galactosidase enzyme of Bacillus circulans ATCC 31382

FEBS Open Bio, 2014
The Bacillus circulans ATCC 31382 β-galactosidase (BgaD) is a retaining-type glycosidase of glycoside hydrolase family 2 (GH2). Its commercial enzyme preparation, Biolacta N5, is used for commercial-scale production of galacto-oligosaccharides (GOS). The
Jelle B. Bultema, Bas J.H. Kuipers, Lubbert Dijkhuizen   +2 more
doaj   +1 more source