ميزان اتوآنتیبادی ضد گلوتاميک اسيد در بيماران ديابتی نوع دو و وابستگان درجه اول آنها [PDF]
, 2004 آنزيم گلوتاميک اسيد دکربوکسيلاز( GAD ) که مسئول تبديل گلوتاميک اسيد به گاما آمينوبوتيريک اسيد است يک نوروترانسميتر مهاری غالب در سيستم اعصاب مرکزی میباشد.
فيروزرای, محسن +3 more
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Long‐term remission of type B insulin resistance syndrome with immunotherapy: A case report
Journal of Diabetes Investigation, Volume 17, Issue 3, Page 542-545, March 2026.ABSTRACT We report long‐term remission in a patient with type B insulin resistance achieved with a combination of immunotherapies. A 55‐year‐old Japanese man presented with nocturnal hypoglycemia and cytopenia. He also had postprandial hyperglycemia due to severe insulin resistance, which was difficult to manage using high‐dose insulin and recombinant ...
Erika Egawa +3 more
wiley +1 more source
Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse. [PDF]
, 1995 Insulin-dependent diabetes mellitus (IDDM) is thought to be an immunologically mediated disease resulting in the complete destruction of the insulin-producing islets of Langerhans.
Bluestone, JA +7 more
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Unraveling A‐β+ ketosis‐prone diabetes: An evolving diagnosis with an elusive pathogenesis
Journal of Diabetes Investigation, Volume 17, Issue 3, Page 381-391, March 2026.ABSTRACT Since the discovery of insulin over a century ago, how we conceptualize, describe and treat diabetes has evolved, paving the way for the identification of distinct diabetes subgroups and individualized treatment options. Historically, the term ketosis‐prone diabetes (KPD) has comprised a group of diabetes syndromes characterized by severe ...
Nina Suda +3 more
wiley +1 more source
Analysis of Receptor’s Distribution in Entorhinal Cortex after Induction of Spreading Depression in Juvenile Rats [PDF]
, 2015 Spreading depression (SD), discovered by Leao in 1944, is a pathophysiological wave which propagates slowly in the brain (3 mm/min) and cause dramatic ionic and hemodynamic changes.
Alizadeh, L., Ghaemi, A., Lotfinia, A.A.
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Characteristics of type 1 diabetes in Northwest China: A multicenter hospital‐based study
Journal of Diabetes Investigation, Volume 17, Issue 3, Page 411-419, March 2026.This study provided an overview of the characteristics of type 1 diabetes patients in Northwest China, a region with low incidence and limited healthcare resources, highlighting the necessity of enhancing public awareness and long‐term disease education and management. ABSTRACT Objective To comprehensively analyze the characteristics of type 1 diabetes
Yue Zhang +5 more
wiley +1 more source
Baculovirus-Mediated Expression of Human 65 kDa and 67 kDa Glutamic Acid Decarboxylases in SF9 Insect Cells and Their Relevance in Diagnosis of Insulin-Dependent Diabetes Mellitus [PDF]
, 1993 cDNAs coding for the full-length human 65 and 67 kDa glutamic acid decarboxylases (GAD65 and GAD67) were amplified from pancreas and hippocampus cDNA libraries by polymerase chain reaction, respectively. Both cDNAs were inserted into a baculovirus vector
Abney, Charles C. +9 more
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A High‐Resolution Transcriptomic Atlas of Cell Types in the Ventral Visual Thalamus
Journal of Neurochemistry, Volume 170, Issue 3, March 2026.Visual information from the eyes travels from retinal ganglion cells (RGCs) to reach the brain through several relay centers. One of these centers, the ventral lateral geniculate nucleus (vLGN), is much less understood than others. In this study, we created the first detailed map of the different cell types found in the mouse vLGN.
Katelyn Stebbins +5 more
wiley +1 more source
Adrenarche as a regulator of sensitivity to early adversity
Journal of Neuroendocrinology, Volume 38, Issue 3, March 2026.Abstract The human brain is highly sensitive to early adversity, which can have long‐term consequences for later mental health. It is also a time of rapid learning of social, motor and other skills, including language. It is proposed that pre‐adrenarche, the only epoch in human development in which cortisol is not accompanied by dehydroepiandrosterone (
J. Herbert
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Aspinous and sparsely-spinous stellate neurons in the visual cortex of rats contain glutamic acid decarboxylase. [PDF]
, 1978 Glutamic acid decarboxylase (GAD), the enzyme that synthesizes the neurotransmitter gamma-amino-butyric acid (GABA), has been localized in the rat visual cortex by immunocytochemical methods with both light and electron microscopy.
Ribak, CE
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