Results 41 to 50 of about 17,633 (189)
Nature Communications, 2016 Cancer cells have previously been shown to be addicted to glutamine and glutaminase enzyme activity. Here, the authors show that overexpression of the JUN proto-oncogene in breast cancer cells regulates glutaminaseexpression and is sufficient to confer ...
Michael J. Lukey +4 more
doaj +1 more source
A new extracellular glutaminase and urease-free l-asparaginase from Meyerozyma guilliermondii [PDF]
, 2023 Aline Ratuchne +4 more
openalex +1 more source
De novo MYC addiction as an adaptive response of cancer cells to CDK4/6 inhibition
Molecular Systems Biology, 2017 Cyclin‐dependent kinases (CDK) are rational cancer therapeutic targets fraught with the development of acquired resistance by tumor cells. Through metabolic and transcriptomic analyses, we show that the inhibition of CDK4/6 leads to a metabolic ...
Míriam Tarrado‐Castellarnau +6 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Glutaminase (EC 3.5.1.2) can catalyze the deamidation of glutamine, which has been used to improve umami taste in oriental fermented foods. However, a high salt concentration is still a fundamental challenge for glutaminase application, especially in soy
Song Liu +7 more
doaj +1 more source
p63 regulates glutaminase 2 expression [PDF]
Cell Cycle, 2013 The transcription factor p63 is critical for many biological processes, including development and maintenance of epidermal tissues and tumorigenesis. Here, we report that the TAp63 isoforms regulate cell metabolism through the induction of the mitochondrial glutaminase 2 (GLS2) gene both in primary cells and tumor cell lines.
Giacobbe, A +12 more
openaire +5 more sources
Supplementary Figure 2 from Dibenzophenanthridines as Inhibitors of Glutaminase C and Cancer Cell Proliferation [PDF]
, 2023 William P. Katt +3 more
openalex +1 more source
Supplementary Figure 7 from Inhibition of Glutaminase Preferentially Slows Growth of Glioma Cells with Mutant IDH1 [PDF]
, 2023 Meghan J. Seltzer +11 more
openalex +1 more source
Open Medicine, 2023 Hepatocellular carcinoma (HCC) is a frequently diagnosed malignancy with a high mortality rate. Cisplatin (CDDP) is a widely applied anti-cancer drug. However, a large population of liver cancer patients developed CDDP resistance.
Tian Ruimin +3 more
doaj +1 more source
مجله دانشگاه علوم پزشکی گرگان, 2011 Background and Objective: Celiac is a hereditary disease presented with chronic inflammation of small intestine. Several studies supposed a relationship between Celiac disease and Inflammatory Bowel Disease (IBD). Tissue trans-glutaminase antibody is one
Amiriani T +9 more
doaj
Glutamine and Glutaminase in Blood
Clinical Chemistry, 1956 Abstract A convenient and accurate procedure for the determination of glutaminase activity and glutamine in blood has been described. Kidney homogenate from rats made acidotic by feeding NH4CL was used as a glutaminase source and the Conway microdiffusion method was used to determine ammonia.
J, BRUTON, F L, IBER
openaire +2 more sources