Results 61 to 70 of about 17,633 (189)
Neonatal Encephalopathy due to Glutaminase Deficiency in a Neonate
Identifying neurometabolic disorders that lead to neonatal encephalopathy is difficult, and access to exome sequencing is a significant advantage in developing countries.
Unnati Achanta +5 more
doaj +1 more source
HuR controls glutaminase RNA metabolism
AbstractGlutaminase (GLS) is directly related to cell growth and tumor progression, making it a target for cancer treatment. The RNA-binding protein HuR (encoded by the ELAVL1 gene) influences mRNA stability and alternative splicing. Overexpression of ELAVL1 is common in several cancers, including breast cancer. Here we show that HuR regulates GLS mRNA
Douglas Adamoski +7 more
openaire +3 more sources
Glutamine metabolism, a double agent combating or fuelling hepatocellular carcinomaKey points
Summary: The reprogramming of glutamine metabolism is a key event in cancer more generally and in hepatocellular carcinoma (HCC) in particular. Glutamine consumption supplies tumours with ATP and metabolites through anaplerosis of the tricarboxylic acid ...
Razan Abou Ziki, Sabine Colnot
doaj +1 more source
In vivo activity of glutaminase in the brain of hyperammonaemic rats measured by 15N nuclear magnetic resonance [PDF]
Keiko Kanamori, Brian D. Ross
openalex +1 more source
Photoreceptor loss results in vision loss in many blinding diseases, and metabolic dysfunction underlies photoreceptor degeneration. So, exploiting photoreceptor metabolism is an attractive strategy to prevent vision loss.
Moloy T Goswami +13 more
doaj +1 more source
Glutamine catabolism by heart muscle. Properties of phosphate-activated glutaminase [PDF]
David Nelson +2 more
openalex +1 more source
Control of Rat‐Liver Glutaminase by Ammonia and pH [PDF]
Arthur J. Verhoeven +3 more
openalex +1 more source

