Results 61 to 70 of about 17,633 (189)

Neonatal Encephalopathy due to Glutaminase Deficiency in a Neonate

open access: yesClinical Case Reports
Identifying neurometabolic disorders that lead to neonatal encephalopathy is difficult, and access to exome sequencing is a significant advantage in developing countries.
Unnati Achanta   +5 more
doaj   +1 more source

HuR controls glutaminase RNA metabolism

open access: yesNature Communications
AbstractGlutaminase (GLS) is directly related to cell growth and tumor progression, making it a target for cancer treatment. The RNA-binding protein HuR (encoded by the ELAVL1 gene) influences mRNA stability and alternative splicing. Overexpression of ELAVL1 is common in several cancers, including breast cancer. Here we show that HuR regulates GLS mRNA
Douglas Adamoski   +7 more
openaire   +3 more sources

Glutamine metabolism, a double agent combating or fuelling hepatocellular carcinomaKey points

open access: yesJHEP Reports
Summary: The reprogramming of glutamine metabolism is a key event in cancer more generally and in hepatocellular carcinoma (HCC) in particular. Glutamine consumption supplies tumours with ATP and metabolites through anaplerosis of the tricarboxylic acid ...
Razan Abou Ziki, Sabine Colnot
doaj   +1 more source

Glutamine catabolism supports amino acid biosynthesis and suppresses the integrated stress response to promote photoreceptor survival

open access: yeseLife
Photoreceptor loss results in vision loss in many blinding diseases, and metabolic dysfunction underlies photoreceptor degeneration. So, exploiting photoreceptor metabolism is an attractive strategy to prevent vision loss.
Moloy T Goswami   +13 more
doaj   +1 more source

Supplementary Materials and Methods from Antitumor Activity of the Glutaminase Inhibitor CB-839 in Triple-Negative Breast Cancer

open access: gold, 2023
Matt I. Gross   +19 more
openalex   +1 more source

Control of Rat‐Liver Glutaminase by Ammonia and pH [PDF]

open access: bronze, 1983
Arthur J. Verhoeven   +3 more
openalex   +1 more source

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