Results 21 to 30 of about 740,346 (304)

Enteral Glutamine Modulates Renal Glutamine Utilization [PDF]

open access: yesThe Journal of Nutrition, 1996
Enteral glutamine feeding effect on renal glutamine utilization was assessed from the perspective of gamma glutamyltransferase activity-dependent cellular glutamate modulation of phosphate-dependent glutaminase. After 4d, rats fed an elemental diet supplemented with glutamine exhibited a 2 1 % higher kidney glutamate content and 27% reduction in ...
T, Welbourne, X, Mu, S, Evans
openaire   +2 more sources

Regulation of osmoadaptation in the moderate halophile Halobacillus halophilus : chloride, glutamate and switching osmolyte strategies [PDF]

open access: yes, 2008
The moderate halophile Halobacillus halophilus is the paradigm for chloride dependent growth in prokaryotes. Recent experiments shed light on the molecular basis of the chloride dependence that is reviewed here.
Saum, Stephan H., Müller, Volker
core   +1 more source

Therapeutic Potential of Glutamine Pathway in Lung Cancer

open access: yesFrontiers in Oncology, 2022
Cancer cells tend to obtain the substances needed for their development depending on altering metabolic characteristics. Among the reorganized metabolic pathways, Glutamine pathway, reprogrammed to be involved in the physiological process including ...
Enyu Tang   +7 more
doaj   +1 more source

Oligodendroglioma cells lack glutamine synthetase and are auxotrophic for glutamine, but do not depend on glutamine anaplerosis for growth [PDF]

open access: yes, 2018
In cells derived from several types of cancer, a transcriptional program drives high consumption of glutamine (Gln), which is used for anaplerosis, leading to a metabolic addiction for the amino acid. Low or absent expression of Glutamine Synthetase (GS),
Andreoli, Roberta   +8 more
core   +2 more sources

Glutamine supplementation [PDF]

open access: yesAnnals of Intensive Care, 2011
Intravenous glutamine supplementation is standard care when parenteral nutrition is given for critical illness. There are data of a reduced mortality when glutamine supplementation is given. In addition, standard commercial products for parenteral nutrition do not contain any glutamine due to glutamine instability in aqueous solutions. For the majority
openaire   +2 more sources

An Intrinsic Alkalization Circuit Turns on mntP Riboswitch under Manganese Stress in Escherichia coli

open access: yesMicrobiology Spectrum, 2022
The trace metal manganese in excess affects iron-sulfur cluster and heme-protein biogenesis, eliciting cellular toxicity. The manganese efflux protein MntP is crucial to evading manganese toxicity in bacteria.
Arunima Kalita   +4 more
doaj   +1 more source

Glutamine Transport and the Role of the Glutamine Translocator in Chloroplasts [PDF]

open access: yesPlant Physiology, 1988
The transport of l-[(14)C]glutamine in oat (Avena sativa L.) and spinach (Spinacia oleracea L.) chloroplasts was studied by a conventional single-layer and a newly developed stable double-layer silicone oil filtering system. [(14)C]Glutamine was actively transported into oat chloroplasts against a concentration gradient.
J, Yu, K C, Woo
openaire   +2 more sources

Glutamine Phosphoribosylpyrophosphate Amidotransferase-independent Phosphoribosyl Amine Synthesis from Ribose 5-Phosphate and Glutamine or Asparagine [PDF]

open access: yes, 2007
Phosphoribosylamine (PRA) is the first intermediate in the common pathway to purines and thiamine and is generated in bacteria by glutamine phosphoribosylpyrophosphate (PRPP) amidotransferase (EC 2.4.2.14) from PRPP and glutamine.
Downs, Diana M.   +2 more
core   +2 more sources

Glutamine and Its Effects on the Intestine

open access: yesCanadian Journal of Gastroenterology, 1991
Glutamine, an amino acid, is the principal energy substrate for small intestinal cells. It also acts as a nitrogen carrier through its amide nitrogen. Arterial glutamine is supported by net synthesis in skeletal muscle.
Paul E Hardy   +3 more
doaj   +1 more source

Environmental cystine drives glutamine anaplerosis and sensitizes cancer cells to glutaminase inhibition

open access: yeseLife, 2017
Many mammalian cancer cell lines depend on glutamine as a major tri-carboxylic acid (TCA) cycle anaplerotic substrate to support proliferation. However, some cell lines that depend on glutamine anaplerosis in culture rely less on glutamine catabolism to ...
Alexander Muir   +5 more
doaj   +1 more source

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