Results 21 to 30 of about 538,260 (299)
The trace metal manganese in excess affects iron-sulfur cluster and heme-protein biogenesis, eliciting cellular toxicity. The manganese efflux protein MntP is crucial to evading manganese toxicity in bacteria.
Arunima Kalita +4 more
doaj +1 more source
Glutamine supplementation [PDF]
Intravenous glutamine supplementation is standard care when parenteral nutrition is given for critical illness. There are data of a reduced mortality when glutamine supplementation is given. In addition, standard commercial products for parenteral nutrition do not contain any glutamine due to glutamine instability in aqueous solutions. For the majority
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Enteral Glutamine Modulates Renal Glutamine Utilization [PDF]
Enteral glutamine feeding effect on renal glutamine utilization was assessed from the perspective of gamma glutamyltransferase activity-dependent cellular glutamate modulation of phosphate-dependent glutaminase. After 4d, rats fed an elemental diet supplemented with glutamine exhibited a 2 1 % higher kidney glutamate content and 27% reduction in ...
T, Welbourne, X, Mu, S, Evans
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Aminosäuren – Leitlinie Parenterale Ernährung, Kapitel 4 [PDF]
Protein catabolism should be reduced and protein synthesis promoted with parenteral nutrion (PN). Amino acid (AA) solutions should always be infused with PN. Standard AA solutions are generally used, whereas specially adapted AA solutions may be required
Blumenstein, I +15 more
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Glutamine and Its Effects on the Intestine
Glutamine, an amino acid, is the principal energy substrate for small intestinal cells. It also acts as a nitrogen carrier through its amide nitrogen. Arterial glutamine is supported by net synthesis in skeletal muscle.
Paul E Hardy +3 more
doaj +1 more source
Glutamine Transport and the Role of the Glutamine Translocator in Chloroplasts [PDF]
The transport of l-[(14)C]glutamine in oat (Avena sativa L.) and spinach (Spinacia oleracea L.) chloroplasts was studied by a conventional single-layer and a newly developed stable double-layer silicone oil filtering system. [(14)C]Glutamine was actively transported into oat chloroplasts against a concentration gradient.
J, Yu, K C, Woo
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PET Imaging of Active Invasive Fungal Infections with d‑[5-11C]-Glutamine
The increasing prevalence and severity of invasive fungal infections (IFIs), especially in immunocompromised populations, has amplified the need for rapid diagnosis of fungal pathogens.
Orhan K. Öz (1877377) +6 more
core +1 more source
Many mammalian cancer cell lines depend on glutamine as a major tri-carboxylic acid (TCA) cycle anaplerotic substrate to support proliferation. However, some cell lines that depend on glutamine anaplerosis in culture rely less on glutamine catabolism to ...
Alexander Muir +5 more
doaj +1 more source
Metabolic Analysis of DFO-Resistant Huh7 Cells and Identification of Targets for Combination Therapy
Hepatocellular carcinoma (HCC) is one of the most refractory cancers with a high rate of recurrence. Iron is an essential trace element, and iron chelation has garnered attention as a novel therapeutic strategy for cancer.
Koichi Fujisawa +4 more
doaj +1 more source
The Regulation of Glutamine Metabolism in Candida utilis: the Role of Glutamine in the Control of Glutamine Synthetase [PDF]
SUMMARY: In Candida utilis, the amount of glutamine synthetase is finely attuned to the availability of ammonia in the culture medium, and any change in ammonia availability results in a compensatory adjustment to enzyme level. In yeast growing with different sources of nitrogen there was a good inverse correlation between the rate of enzyme synthesis ...
A R, Ferguson, A P, Sims
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