Results 1 to 10 of about 78,410 (212)
The Distinctive Regulation of Cyanobacterial Glutamine Synthetase [PDF]
Life, 2018 Glutamine synthetase (GS) features prominently in bacterial nitrogen assimilation as it catalyzes the entry of bioavailable nitrogen in form of ammonium into cellular metabolism. The classic example, the comprehensively characterized GS of enterobacteria,
Bolay, Paul +3 more
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Congenital glutamine deficiency with glutamine synthetase mutations [PDF]
New England Journal of Medicine, 2006 Jalan, Rajiv, Rose, Christopher
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Regulation of synthesis of glutamine synthetase by adenylylated glutamine synthetase. [PDF]
Proceedings of the National Academy of Sciences, 1975 We have examined three mutants of Klebsiella aerogenes whose genetic lesions (glnB, glnD, and glnE) are in loci unlinked to the structural gene for glutamine sythetase (glnA) and in which the control of both the level and state of adenylylation of glutamine synthetase is altered. Each mutation alters a different component of the adenylylation system of
Boris Magasanik +2 more
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Role of glutamine synthetase in angiogenesis beyond glutamine synthesis [PDF]
Nature, 2018 Glutamine synthetase, encoded by the gene GLUL, is an enzyme that converts glutamate and ammonia to glutamine. It is expressed by endothelial cells, but surprisingly shows negligible glutamine-synthesizing activity in these cells at physiological glutamine levels.
Jaap D. van Buul +46 more
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Astrocytes and Glutamine Synthetase in Epileptogenesis [PDF]
Journal of Neuroscience Research, 2018 AbstractThe cellular, molecular, and metabolic mechanisms that underlie the development of mesial temporal lobe epilepsy are incompletely understood. Here we review the role of astrocytes in epilepsy development (a.k.a. epileptogenesis), particularly astrocyte pathologies related to: aquaporin 4, the inwardly rectifying potassium channel Kir4.1 ...
Peter R. Patrylo +4 more
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Glutamine synthetase in muscle and kidney [PDF]
Biochemical Journal, 1970 1. Glutamine synthetase activity has been determined in extracts of rat cardiac and skeletal muscle and kidney, after treatment to ensure that the rate of synthesis was proportional to time of incubation and to amount of extract added. The activity was measured by two methods, with hydroxylamine as substrate. 2.
J. H. Ottaway, Khalid Iqbal
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Glutamine synthetase activity during embryonic and larval development of the silkworm Bombyx mori L. and role of a JH analogue [PDF]
, 1992 Silkworm eggs of diapause nature were chilled or treated with hydrochloric acid. Glutamine synthetase activity in such treated eggs was present soon after the treatment, whereas in non-diapause eggs it was not detectable until 24 h after the start of ...
Krishnamoorthy, R.V. +2 more
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Formation of Glutamine and Activities of Glutamine Synthetase in Goats
The Japanese Journal of Veterinary Science, 1977 When goats were administered orally with urea in a dose of 0.3 g per kg of body weight, the blood concentration of glutamine-N in the jugular vein increased to about 6μg per ml of plasma, reflecting the removal of ammonia by forming glutamine in the animal body. The blood glutamine seemed to undergo a more rapid turnover than the blood urea.
Hajime Matsumoto, Yu Ide
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Expression of Glutamine Synthetase in Macrophages [PDF]
Journal of Histochemistry & Cytochemistry, 2000 We studied the expression of glutamine synthetase in liver macrophages (Kupffer cells, KCs) in situ and in culture. Glutamine synthetase was detectable at the mRNA and protein level in freshly isolated and short-term-cultured rat liver macrophages. Enzyme activity and protein content were about 9% of that in liver parenchymal cells.
Thorsten Peters-Regehr +3 more
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Astrocyte glutamine synthetase : pivotal in health and disease [PDF]
, 2013 The multifunctional properties of astrocytes signify their importance in brain physiology and neurological function. In addition to defining the brain architecture, astrocytes are primary elements of brain ion, pH and neurotransmitter homoeostasis.
Parpura, Vladimir +2 more
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