Results 31 to 40 of about 87,161 (272)

Glutamine metabolic reprogramming in hepatocellular carcinoma

Frontiers in Molecular Biosciences, 2023
Hepatocellular carcinoma (HCC) is a lethal disease with limited management strategies and poor prognosis. Metabolism alternations have been frequently unveiled in HCC, including glutamine metabolic reprogramming.
Yanyan Ye, Bodong Yu, Bodong Yu, Hua Wang, Hua Wang, Fengming Yi, Fengming Yi   +6 more
doaj   +1 more source

Genes for asparagine metabolism in Lotus japonicus : differential expression and interconnection with photorespiration [PDF]

, 2017
Background: Asparagine is a very important nitrogen transport and storage compound in plants due to its high nitrogen/carbon ratio and stability.
Betti, Marco, Credali, Alfredo, García Calderón, Margarita, Márquez Cabeza, Antonio José, Pérez Delgado de Torres, Carmen María, Vega Piqueres, José María   +5 more
core   +1 more source

Outgrowth of Rice Tillers Requires Availability of Glutamine in the Basal Portions of Shoots

Rice, 2018
Background Our previous studies concluded that metabolic disorder in the basal portions of rice shoots caused by a lack of cytosolic glutamine synthetase1;2 (GS1;2) resulted in a severe reduction in the outgrowth of tillers.
Miwa Ohashi, Keiki Ishiyama, Soichi Kojima, Noriyuki Konishi, Kazuhiro Sasaki, Mitsue Miyao, Toshihiko Hayakawa, Tomoyuki Yamaya   +7 more
doaj   +1 more source

Starve Cancer Cells of Glutamine: Break the Spell or Make a Hungry Monster? [PDF]

, 2019
Distinct from normal differentiated tissues, cancer cells reprogram nutrient uptake and utilization to accommodate their elevated demands for biosynthesis and energy production.
Jiang, Jie, Srivastava, Sankalp, Zhang, Ji   +2 more
core   +1 more source

Intraspecfic variation in cold-temperature metabolic phenotypes of Arabidopsis lyrata ssp petraea [PDF]

, 2009
Atmospheric temperature is a key factor in determining the distribution of a plant species. Alongside this, plant populations growing at the margin of their range may exhibit traits that indicate genetic differentiation and adaptation to their local ...
A Suzuki, AB Bleeckerl, B Jonsell, B Usadel, B Vinocur, BH Miesak, C Alonso-Blanco, CD Thomas, CL Guy, D Cook, F Kaplan, F Kaplan, F. Ian Woodward, GR Gray, GR Walther, GR Walther, HM Lam, HM Lam, HM Lam, IC Oliveira, J Kilian, J Klotke, L Skøt, M Stitt, MA Hannah, Matthew P. Davey, MF Thomashow, MJ Clauss, MJ Clauss, MP Davey, N Smirnoff, NR Sackville Hamilton, OK Atkin, P Vergeer, RC Meyer, RJ Li, S Sagisaka, TK Peterman, W. Paul Quick, Y Zhen, Å Strand   +40 more
core   +1 more source

The Rhizobium GstI Protein Reduces the NH4+ Assimilation Capacity of Rhizobium leguminosarum

Molecular Plant-Microbe Interactions, 2001
We show that the protein encoded by the glutamine synthetase translational inhibitor (gstI) gene reduces the NH4+ assimilation capacity of Rhizobium leguminosarum.
Rosarita Tatè, Luigi Mandrich, Maria R. Spinosa, Anna Riccio, Alessandro Lamberti, Maurizio Iaccarino, Eduardo J. Patriarca   +6 more
doaj   +1 more source

Glutamine metabolism in the proliferation of GS-expression pituitary tumor cells

Endocrine Connections, 2020
Objective: Many cancer cells cannot survive without exogenous glutamine (Gln); however, cancer cells expressing glutamine synthetase (GS) do not have this restriction.
Jintao Hu, Qingbo Chen, Xiao Ding, Xin Zheng, Xuefeng Tang, Song Li, Hui Yang   +6 more
doaj   +1 more source

Molecular mechanisms of adaptation of the moderately halophilic bacterium Halobacillis halophilus to its environment [PDF]

, 2013
The capability of osmoadaptation is a prerequisite of organisms that live in an environment with changing salinities. Halobacillus halophilus is a moderately halophilic bacterium that grows between 0.4 and 3 M NaCl by accumulating both chloride and ...
Hänelt, Inga, Müller, Volker
core   +2 more sources

The intracellular location of nitrogen metabolism enzymes in Pisum arvense L. roots

Acta Societatis Botanicorum Poloniae, 2014
The time course changes of nitrate assimilation enzymes and their distribution has been studied in Pisum arvense roots. The results indicate that nitrate reductase (EC 1.6.6.2) and glutamine synthetase (EC 6.3.1.2) are present in the soluble fraction ...
Grażyna Kłobus, Genowefa Kłobus-Dobosz, Józef Buczek   +2 more
doaj   +1 more source

Abnormalities in Glutamate Metabolism and Excitotoxicity in the Retinal Diseases

Scientifica, 2013
In the physiological condition, glutamate acts as an excitatory neurotransmitter in the retina. However, excessive glutamate can be toxic to retinal neurons by overstimulation of the glutamate receptors.
Makoto Ishikawa
doaj   +1 more source