Results 31 to 40 of about 200,780 (234)
Patologìâ, 2012 Adult rabbits with experimental glaucoma were used in this study. We studied glutamate and glutamine levels and glutamine synthetase, glutamate oxidase and glutaminase activity in the eye tissue during glaucoma process.
V. M. Serdyuk
doaj +1 more source
The role of cytosolic glutamine synthetase in wheat [PDF]
, 2001 The definitive version is available at www.blackwell-synergy.comThe role of glutamine synthetase (GS; EC 6.3.1.2) was studied in wheat. GS isoforms were separated by HPLC and the two major leaf isoforms (cytosolic GS1 and chloroplastic GS2) were found to
Rong, H. L. +9 more
core +1 more source
Glutamine versus ammonia utilization in the NAD synthetase family. [PDF]
PLoS ONE, 2012 NAD is a ubiquitous and essential metabolic redox cofactor which also functions as a substrate in certain regulatory pathways. The last step of NAD synthesis is the ATP-dependent amidation of deamido-NAD by NAD synthetase (NADS).
Jessica De Ingeniis +5 more
doaj +1 more source
Leukemia Cells Resistant to Glutamine Deprivation Express Glutamine Synthetase Protein
Turkish Journal of Hematology, 2022 Objective: Low glutamine levels have been shown in tumor environments for several cancer subtypes. Therefore, it has been suggested that cancer cells rewire their metabolism to adopt low nutrient levels for survival and proliferation.
Burcu Yücel, Saniye Ada
doaj +1 more source
Formation of Glutamine and Activities of Glutamine Synthetase in Goats
The Japanese Journal of Veterinary Science, 1977 When goats were administered orally with urea in a dose of 0.3 g per kg of body weight, the blood concentration of glutamine-N in the jugular vein increased to about 6μg per ml of plasma, reflecting the removal of ammonia by forming glutamine in the animal body. The blood glutamine seemed to undergo a more rapid turnover than the blood urea.
IDE, Yu, MATSUMOTO, Hajime
openaire +3 more sources
Glutamine synthetase is necessary for sarcoma adaptation to glutamine deprivation and tumor growth
Oncogenesis, 2019 Despite a growing body of knowledge about the genomic landscape and molecular pathogenesis of sarcomas, translation of basic discoveries into targeted therapies and significant clinical gains has remained elusive.
Sameer H Issaq +3 more
semanticscholar +1 more source
Proteolytic Inactivation of Glutamine Synthetase in Extracts From Wheat Leaves: Effects of pH, Inorganic Ions and Metabolites [PDF]
, 1994 Glutamine synthetase in extracts from young wheat (Triticum aestivum L.) leaves was quite stable at pH 7.0-9.0, whereas it was remarkably more labile below and above this range.
Fischer, Andreas +4 more
core +1 more source
In vitro suppression of inflammatory cytokine response by methionine sulfoximine
Journal of Inflammation, 2018 Background The glutamine synthetase inhibitor methionine sulfoximine (MSO), shown previously to prevent death caused by an inflammatory liver response in mice, was tested on in vitro production of cytokines by mouse peritoneal macrophages triggered with ...
Tyler J. Peters +2 more
doaj +1 more source
Frontiers in Neuroscience, 2021 Glutamate is the main excitatory amino acid acting at the level of pre and postsynaptic neurons, as well as in glial cells. It is involved in the coordinated modulation of energy metabolism, glutamine synthesis, and ammonia detoxification.
Catya Jiménez-Torres +5 more
doaj +1 more source
Transgenic expression of plastidic glutamine synthetase increases nitrogen uptake and yield in wheat
Plant Biotechnology Journal, 2018 Summary The plastidic glutamine synthetase isoform (GS2) plays a key role in nitrogen (N) assimilation. We introduced TaGS2‐2Abpro::TaGS2‐2Ab, the favourable allele of TaGS2‐2A in the winter wheat (Triticum aestivum) variety Ji5265. Transgenic expression
M. Hu +8 more
semanticscholar +1 more source