Results 21 to 30 of about 119,068 (185)

Cloning and expression of murine glutamine synthetase.

open access: yes, 1989
Cloning and expression of murine glutamine ...
Scott Randell. Magnuson (7997663)
core   +6 more sources

Oligodendrocytes Support Neuronal Glutamatergic Transmission via Expression of Glutamine Synthetase

open access: yesCell Reports, 2019
Summary: Glutamate has been implicated in a wide range of brain pathologies and is thought to be metabolized via the astrocyte-specific enzyme glutamine synthetase (GS).
Wendy Xin   +7 more
doaj   +1 more source

Leukemia Cells Resistant to Glutamine Deprivation Express Glutamine Synthetase Protein

open access: yesTurkish Journal of Hematology, 2022
Objective: Low glutamine levels have been shown in tumor environments for several cancer subtypes. Therefore, it has been suggested that cancer cells rewire their metabolism to adopt low nutrient levels for survival and proliferation.
Burcu Yücel, Saniye Ada
doaj   +1 more source

Formation of Glutamine and Activities of Glutamine Synthetase in Goats

open access: yesThe Japanese Journal of Veterinary Science, 1977
When goats were administered orally with urea in a dose of 0.3 g per kg of body weight, the blood concentration of glutamine-N in the jugular vein increased to about 6μg per ml of plasma, reflecting the removal of ammonia by forming glutamine in the animal body. The blood glutamine seemed to undergo a more rapid turnover than the blood urea.
IDE, Yu, MATSUMOTO, Hajime
openaire   +3 more sources

Crystal structure of the Large Type III Glutamine Synthetase from Bacteroides Fragilis [PDF]

open access: yes, 2010
Glutamine synthetases are one of the most ancient functioning enzymes in existence and these large oligomeric complexes are found in all extant forms of life where they play a critical role in nitrogen metabolism.
van Rooyen, Jason M
core   +1 more source

In vitro suppression of inflammatory cytokine response by methionine sulfoximine

open access: yesJournal of Inflammation, 2018
Background The glutamine synthetase inhibitor methionine sulfoximine (MSO), shown previously to prevent death caused by an inflammatory liver response in mice, was tested on in vitro production of cytokines by mouse peritoneal macrophages triggered with ...
Tyler J. Peters   +2 more
doaj   +1 more source

Acute Liver Toxicity Modifies Protein Expression of Glutamate Transporters in Liver and Cerebellar Tissue

open access: yesFrontiers in Neuroscience, 2021
Glutamate is the main excitatory amino acid acting at the level of pre and postsynaptic neurons, as well as in glial cells. It is involved in the coordinated modulation of energy metabolism, glutamine synthesis, and ammonia detoxification.
Catya Jiménez-Torres   +5 more
doaj   +1 more source

Glutamine metabolic reprogramming in hepatocellular carcinoma

open access: yesFrontiers in Molecular Biosciences, 2023
Hepatocellular carcinoma (HCC) is a lethal disease with limited management strategies and poor prognosis. Metabolism alternations have been frequently unveiled in HCC, including glutamine metabolic reprogramming.
Yanyan Ye   +6 more
doaj   +1 more source

Outgrowth of Rice Tillers Requires Availability of Glutamine in the Basal Portions of Shoots

open access: yesRice, 2018
Background Our previous studies concluded that metabolic disorder in the basal portions of rice shoots caused by a lack of cytosolic glutamine synthetase1;2 (GS1;2) resulted in a severe reduction in the outgrowth of tillers.
Miwa Ohashi   +7 more
doaj   +1 more source

The Rhizobium GstI Protein Reduces the NH4+ Assimilation Capacity of Rhizobium leguminosarum

open access: yesMolecular Plant-Microbe Interactions, 2001
We show that the protein encoded by the glutamine synthetase translational inhibitor (gstI) gene reduces the NH4+ assimilation capacity of Rhizobium leguminosarum.
Rosarita Tatè   +6 more
doaj   +1 more source

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