Results 41 to 50 of about 87,161 (272)
Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. [PDF]
, 2016 Cellular amino acid uptake is critical for mTOR complex 1 (mTORC1) activation and cell proliferation. However, the regulation of amino acid uptake is not well-understood.
Braas, Daniel +4 more
core +1 more source
Effect of chilling and acclimation on the activity of glutamine synthetase isoforms in maize seedlings [PDF]
Archives of Biological Sciences, 2007 Effects of chilling and acclimation on the activity of cytosolic (GS1) and plastidic (GS2) isoforms of glutamine synthetase (E.C. 6.3.1.2) were studied in chilling-sensitive and acclimation-responsive maize inbred G50.
Simonović Ana D., Anderson M.D.
doaj +1 more source
Ammonia toxicity: from head to toe? [PDF]
, 2016 Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan +6 more
core +1 more source
Brazilian Archives of Biology and Technology, 2006 The arginase tissue distribution, the biochemical properties of the argininolytic system and the subcellular localization of the enzymes carbamoylphosphate synthetase, ornithinecarbamoyl transferase, glutamine synthetase and arginase in Antarctic fish, N.
Edson Rodrigues +2 more
doaj +1 more source
Methionine sulfoximine resistance in Mycobacterium tuberculosis is due to a single nucleotide deletion resulting in increased expression of the major glutamine synthetase, GlnA1 [PDF]
, 2011 We investigated the effect of methionine sulfoximine (MetSox), a potent inhibitor of glutamine synthetase, on Mycobacterium tuberculosis. M. tuberculosis encodes four glutamine synthetases, of which MetSox targets the type I enzyme encoded by glnA1 ...
Butcher, Philip D +3 more
core +2 more sources
Single‐Injection Multi‐Omics Analysis by Direct Infusion Mass Spectrometry
Angewandte Chemie, EarlyView.A high‐throughput direct infusion mass spectrometry platform, enabled by gas‐phase ion mobility separation, supports single‐injection analysis of peptides, polar metabolites, and lipids. Coupled with custom software, it identified ∽1,300 proteins and ∽600 metabolites in ∽4.3 minutes per sample, and demonstrated broad utility in macrophage polarization ...
Yuming Jiang +6 more
wiley +2 more sources
BMC Evolutionary Biology, 2009 Background Although the gene encoding for glutamine synthetase (glnA) is essential in several organisms, multiple glnA copies have been identified in bacterial genomes such as those of the phylum Actinobacteria, notably the mycobacterial species ...
Wiid Ian JF +2 more
doaj +1 more source
Cell Reports, 2019 Summary: Radiation resistance is a critical problem in radiotherapy for cancer. Radiation kills tumor cells mainly through causing DNA damage. Thus, efficiency of DNA damage repair is one of the most important factors that limits radiotherapy efficacy ...
Shujun Fu +15 more
doaj +1 more source
Reassimilation of Photorespiratory Ammonium in Lotus japonicus Plants Deficient in Plastidic Glutamine Synthetase. [PDF]
PLoS ONE, 2015 It is well established that the plastidic isoform of glutamine synthetase (GS2) is the enzyme in charge of photorespiratory ammonium reassimilation in plants.
Carmen M Pérez-Delgado +3 more
doaj +1 more source
In-vivo modification of Azotobacter-chroococcum glutamine-synthetase [PDF]
, 1994 against glutamine synthetase of the unicellular cyanobacterium Synechocystis sp. strain PCC 6803 immunoreacted with glutamine synthetase from the N2-fixing heterotrophic bacterium Azotobacter chroococcum. In Western-blotting experiments this antibody
Aneque Guerrero, Antonio +2 more
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