Glutamine metabolic reprogramming in hepatocellular carcinoma
Frontiers in Molecular Biosciences, 2023 Hepatocellular carcinoma (HCC) is a lethal disease with limited management strategies and poor prognosis. Metabolism alternations have been frequently unveiled in HCC, including glutamine metabolic reprogramming.
Yanyan Ye +6 more
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Dexamethasone regulates glutamine synthetase expression in rat skeletal muscles [PDF]
, 1988 The regulation of glutamine synthetase expression by dexamethasone was studied in rat skeletal muscles. Daily administration of dexamethasone caused striking enhancement of glutamine synthetase activity in plantaris, soleus, and diaphragm muscles ...
C. Banner +7 more
core +1 more source
Outgrowth of Rice Tillers Requires Availability of Glutamine in the Basal Portions of Shoots
Rice, 2018 Background Our previous studies concluded that metabolic disorder in the basal portions of rice shoots caused by a lack of cytosolic glutamine synthetase1;2 (GS1;2) resulted in a severe reduction in the outgrowth of tillers.
Miwa Ohashi +7 more
doaj +1 more source
Glutamine Synthetase and Glutamine Synthetase‐Like Protein from Human Brain [PDF]
Journal of Neurochemistry, 2000 Abstract: Glutamine synthetase (GS; EC 6.3.1.2), a key enzyme ofglutamate metabolism, and another enzyme possessing highhydroxylamine‐L‐glutamine transferase activity comparable to that of GS andtermed GS‐like protein (GSLP) were purified from human brain concurrently.
I S, Boksha +2 more
openaire +2 more sources
A glutamine riboswitch is a key element for the regulation of glutamine synthetase in cyanobacteria
Nucleic Acids Research, 2018 As the key enzyme of bacterial nitrogen assimilation, glutamine synthetase (GS) is tightly regulated. In cyanobacteria, GS activity is controlled by the interaction with inactivating protein factors IF7 and IF17 encoded by the genes gifA and gifB ...
Stephan Klähn +7 more
semanticscholar +1 more source
Neural control of glutamine synthetase activity in rat skeletal muscles [PDF]
, 1990 The mechanism of glutamine synthetase induction in rat skeletal muscle after denervation or limb immobilization was investigated. Adult male rats were subjected to midthigh section of the sciatic nerve.
C. Banner +6 more
core +1 more source
The Rhizobium GstI Protein Reduces the NH4+ Assimilation Capacity of Rhizobium leguminosarum
Molecular Plant-Microbe Interactions, 2001 We show that the protein encoded by the glutamine synthetase translational inhibitor (gstI) gene reduces the NH4+ assimilation capacity of Rhizobium leguminosarum.
Rosarita Tatè +6 more
doaj +1 more source
Glutamine metabolism in the proliferation of GS-expression pituitary tumor cells
Endocrine Connections, 2020 Objective: Many cancer cells cannot survive without exogenous glutamine (Gln); however, cancer cells expressing glutamine synthetase (GS) do not have this restriction.
Jintao Hu +6 more
doaj +1 more source
The intracellular location of nitrogen metabolism enzymes in Pisum arvense L. roots
Acta Societatis Botanicorum Poloniae, 2014 The time course changes of nitrate assimilation enzymes and their distribution has been studied in Pisum arvense roots. The results indicate that nitrate reductase (EC 1.6.6.2) and glutamine synthetase (EC 6.3.1.2) are present in the soluble fraction ...
Grażyna Kłobus +2 more
doaj +1 more source
Circumstantial evidence for a role of glutamine-synthetase in suicide [PDF]
, 2011 Suicide occurs during depression, schizophrenia and epilepsy. A common denominator of these disorders is the presence of a brain inflammation. Inflammatory cytokines affect function and expression of the glial enzyme glutamine synthetase and post mortem ...
Kalkman, Hans O., Hans O. Kalkman
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