Results 11 to 20 of about 92,131 (300)

Regulation of Glutamine Synthetase

Archives of Biochemistry and Biophysics, 1967
Bennett M. Shapiro, Earl R. Stadtman
  +4 more sources

Congenital glutamine deficiency with glutamine synthetase mutations [PDF]

New England Journal of Medicine, 2006
Jalan, Rajiv, Rose, Christopher
core   +3 more sources

Glutamine Synthetase Sensitivity to Oxidative Modification during Nutrient Starvation in Prochlorococcus marinus PCC 9511. [PDF]

PLoS ONE, 2015
Glutamine synthetase plays a key role in nitrogen metabolism, thus the fine regulation of this enzyme in Prochlorococcus, which is especially important in the oligotrophic oceans where this marine cyanobacterium thrives.
Guadalupe Gómez-Baena, María Agustina Domínguez-Martín, Robert P Donaldson, José Manuel García-Fernández, Jesús Diez   +4 more
doaj   +1 more source

Licensing instead of fueling: Glutamine synthetase promotes mitotic progression via a non-metabolic mechanism

Visualized Cancer Medicine, 2023
A recent report published in Nature Metabolism identified that glutamine synthetase (GS), the only enzyme in mammals to produce glutamine from glutamate, can directly control cancer cell mitosis by governing the APC/C complex via a metabolism-independent
Zhao Jiang-Sha, Yang Jing, Lu Zhimin, Feng Yu-Xiong   +3 more
doaj   +1 more source

Investigating the role of GLUL as a survival factor in cellular adaptation to glutamine depletion via targeted stable isotope resolved metabolomics

Frontiers in Molecular Biosciences, 2022
Cellular glutamine synthesis is thought to be an important resistance factor in protecting cells from nutrient deprivation and may also contribute to drug resistance.
Șafak Bayram, Yasmin Sophiya Razzaque, Sabrina Geisberger, Matthias Pietzke, Matthias Pietzke, Susanne Fürst, Susanne Fürst, Carolina Vechiatto, Martin Forbes, Guido Mastrobuoni, Stefan Kempa   +10 more
doaj   +1 more source

Glutamine Synthetase: Localization Dictates Outcome [PDF]

Genes, 2018
Glutamine synthetase (GS) is the adenosine triphosphate (ATP)-dependent enzyme that catalyses the synthesis of glutamine by condensing ammonium to glutamate. In the circulatory system, glutamine carries ammonia from muscle and brain to the kidney and liver.
Castegna A., Menga A.
openaire   +4 more sources

Glutamine Synthetase and Glutamate Synthase Family Perform Diverse Physiological Functions in Exogenous Hormones and Abiotic Stress Responses in Pyrus betulifolia Bunge (P.be). [PDF]

Plants (Basel)
Zhang W, Yuan S, Liu N, Zhang H, Zhang Y.   +4 more
europepmc   +3 more sources

Ammonia promotes the proliferation of bone marrow-derived mesenchymal stem cells by regulating the Akt/mTOR/S6k pathway

Bone Research, 2022
Ammonia plays an important role in cellular metabolism. However, ammonia is considered a toxic product. In bone marrow-derived mesenchymal stem cells, multipotent stem cells with high expression of glutamine synthetase (GS) in bone marrow, ammonia and ...
Yu Liu, Xiangxian Zhang, Wei Wang, Ting Liu, Jun Ren, Siyuan Chen, Tianqi Lu, Yan Tie, Xia Yuan, Fei Mo, Jingyun Yang, Yuquan Wei, Xiawei Wei   +12 more
doaj   +1 more source

Reduced density of glutamine synthetase immunoreactive astrocytes in different cortical areas in major depression but not in bipolar I disorder

Frontiers in Cellular Neuroscience, 2015
There is increasing evidence for disturbances within the glutamate system in patients with affective disorders, which involve disruptions of the glutamate-glutamine- cycle.
Hans-Gert eBernstein, Gabriela eMeyer-Lotz, Henrik eDobrowlny, Jana eBannier, Johann eSteiner, Martin eWalter, Martin eWalter, Bernhard eBogerts   +7 more
doaj   +1 more source

Glutamine synthetase activity during embryonic and larval development of the silkworm Bombyx mori L. and role of a JH analogue [PDF]

, 1992
Silkworm eggs of diapause nature were chilled or treated with hydrochloric acid. Glutamine synthetase activity in such treated eggs was present soon after the treatment, whereas in non-diapause eggs it was not detectable until 24 h after the start of ...
Krishnamoorthy, R.V., Seshachalam, R.V., Subramanyam, M.V.V.   +2 more
core   +1 more source