Results 21 to 30 of about 216,468 (357)
Reassimilation of Photorespiratory Ammonium in Lotus japonicus Plants Deficient in Plastidic Glutamine Synthetase. [PDF]
PLoS ONE, 2015 It is well established that the plastidic isoform of glutamine synthetase (GS2) is the enzyme in charge of photorespiratory ammonium reassimilation in plants.
Carmen M Pérez-Delgado +3 more
doaj +11 more sources
The glutamine synthetase gene family in
BMC Plant Biology, 2011 Background Glutamine synthetase (GS; EC: 6.3.1.2, L-glutamate: ammonia ligase ADP-forming) is a key enzyme in ammonium assimilation and metabolism of higher plants.
Cánovas Francisco M +5 more
doaj +4 more sources
Nature Communications, 2021 Plants use nitrate, ammonium, and organic nitrogen in the soil as nitrogen sources. Since the elevated CO2 environment predicted for the near future will reduce nitrate utilization by C3 species, ammonium is attracting great interest.
Takushi Hachiya +11 more
semanticscholar +1 more source
Glutamine Synthetase as a Therapeutic Target for Cancer Treatment
International Journal of Molecular Sciences, 2021 The significance of glutamine in cancer metabolism has been extensively studied. Cancer cells consume an excessive amount of glutamine to facilitate rapid proliferation.
Go-woon Kim +7 more
semanticscholar +1 more source
Congenital glutamine deficiency with glutamine synthetase mutations [PDF]
New England Journal of Medicine, 2006 Jalan, Rajiv, Rose, Christopher
core +4 more sources
Differential inhibition of adenylylated and deadenylylated forms of M. tuberculosis glutamine synthetase as a drug discovery platform. [PDF]
PLoS ONE, 2017 Glutamine synthetase is a ubiquitous central enzyme in nitrogen metabolism that is controlled by up to four regulatory mechanisms, including adenylylation of some or all of the twelve subunits by adenylyl transferase.
A Theron +9 more
doaj +1 more source
Regulation of synthesis of glutamine synthetase by adenylylated glutamine synthetase. [PDF]
Proceedings of the National Academy of Sciences, 1975 We have examined three mutants of Klebsiella aerogenes whose genetic lesions (glnB, glnD, and glnE) are in loci unlinked to the structural gene for glutamine sythetase (glnA) and in which the control of both the level and state of adenylylation of glutamine synthetase is altered. Each mutation alters a different component of the adenylylation system of
Boris Magasanik +2 more
openaire +3 more sources
Glutamine Synthetase Sensitivity to Oxidative Modification during Nutrient Starvation in Prochlorococcus marinus PCC 9511. [PDF]
PLoS ONE, 2015 Glutamine synthetase plays a key role in nitrogen metabolism, thus the fine regulation of this enzyme in Prochlorococcus, which is especially important in the oligotrophic oceans where this marine cyanobacterium thrives.
Guadalupe Gómez-Baena +4 more
doaj +1 more source
Visualized Cancer Medicine, 2023 A recent report published in Nature Metabolism identified that glutamine synthetase (GS), the only enzyme in mammals to produce glutamine from glutamate, can directly control cancer cell mitosis by governing the APC/C complex via a metabolism-independent
Zhao Jiang-Sha +3 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2022 Cellular glutamine synthesis is thought to be an important resistance factor in protecting cells from nutrient deprivation and may also contribute to drug resistance.
Șafak Bayram +10 more
doaj +1 more source