Results 21 to 30 of about 91,004 (324)

Reduced density of glutamine synthetase immunoreactive astrocytes in different cortical areas in major depression but not in bipolar I disorder

Frontiers in Cellular Neuroscience, 2015
There is increasing evidence for disturbances within the glutamate system in patients with affective disorders, which involve disruptions of the glutamate-glutamine- cycle.
Hans-Gert eBernstein, Gabriela eMeyer-Lotz, Henrik eDobrowlny, Jana eBannier, Johann eSteiner, Martin eWalter, Martin eWalter, Bernhard eBogerts   +7 more
doaj   +1 more source

Glutamine synthetase activity during embryonic and larval development of the silkworm Bombyx mori L. and role of a JH analogue [PDF]

, 1992
Silkworm eggs of diapause nature were chilled or treated with hydrochloric acid. Glutamine synthetase activity in such treated eggs was present soon after the treatment, whereas in non-diapause eggs it was not detectable until 24 h after the start of ...
Krishnamoorthy, R.V., Seshachalam, R.V., Subramanyam, M.V.V.   +2 more
core   +1 more source

Glutamine synthetase in muscle and kidney [PDF]

Biochemical Journal, 1970
1. Glutamine synthetase activity has been determined in extracts of rat cardiac and skeletal muscle and kidney, after treatment to ensure that the rate of synthesis was proportional to time of incubation and to amount of extract added. The activity was measured by two methods, with hydroxylamine as substrate. 2.
K, Iqbal, J H, Ottaway
openaire   +2 more sources

Possibility of medicinal correction of disorders in metabolic cycle of neurotoxic transmitter glutamate in retina with neurotropic drugs during experimental glaucoma

Patologìâ, 2012
Adult rabbits with experimental glaucoma were used in this study. We studied glutamate and glutamine levels and glutamine synthetase, glutamate oxidase and glutaminase activity in the eye tissue during glaucoma process.
V. M. Serdyuk
doaj   +1 more source

Expression of Glutamine Synthetase in Macrophages [PDF]

Journal of Histochemistry & Cytochemistry, 2000
We studied the expression of glutamine synthetase in liver macrophages (Kupffer cells, KCs) in situ and in culture. Glutamine synthetase was detectable at the mRNA and protein level in freshly isolated and short-term-cultured rat liver macrophages. Enzyme activity and protein content were about 9% of that in liver parenchymal cells.
J G, Bode, T, Peters-Regehr, R, Kubitz, D, Häussinger   +3 more
openaire   +2 more sources

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Oligodendrocytes Support Neuronal Glutamatergic Transmission via Expression of Glutamine Synthetase

Cell Reports, 2019
Summary: Glutamate has been implicated in a wide range of brain pathologies and is thought to be metabolized via the astrocyte-specific enzyme glutamine synthetase (GS).
Wendy Xin, Yevgeniya A. Mironova, Hui Shen, Rosa A.M. Marino, Ari Waisman, Wouter H. Lamers, Dwight E. Bergles, Antonello Bonci   +7 more
doaj   +1 more source

New isoforms and assembly of glutamine synthetase in the leaf of wheat (Triticum aestivum L.). [PDF]

, 2015
Glutamine synthetase (GS; EC 6.3.1.2) plays a crucial role in the assimilation and re-assimilation of ammonia derived from a wide variety of metabolic processes during plant growth and development.
Ma, Xinming, Shi, Lanxin, Theg, Steven M, Wang, Xiaochun, Wei, Yihao   +4 more
core   +1 more source

Formation of Glutamine and Activities of Glutamine Synthetase in Goats

The Japanese Journal of Veterinary Science, 1977
When goats were administered orally with urea in a dose of 0.3 g per kg of body weight, the blood concentration of glutamine-N in the jugular vein increased to about 6μg per ml of plasma, reflecting the removal of ammonia by forming glutamine in the animal body. The blood glutamine seemed to undergo a more rapid turnover than the blood urea.
Y, Ide, H, Matsumoto
openaire   +3 more sources

Dexamethasone enhances glutamine synthetase activity and reduces N-methyl-D-aspartate neurotoxicity in mixed cultures of neurons and astrocytes

AIMS Molecular Science, 2015
Astrocytes are claimed to protect neurons against excitotoxicity by clearing glutamate from the extracellular space and rapidly converting it into glutamine.
Edith Debroas, Carine Ali, Dominique Duval   +2 more
doaj   +1 more source