Results 41 to 50 of about 92,131 (300)

Glutamine metabolism in the proliferation of GS-expression pituitary tumor cells

open access: yesEndocrine Connections, 2020
Objective: Many cancer cells cannot survive without exogenous glutamine (Gln); however, cancer cells expressing glutamine synthetase (GS) do not have this restriction.
Jintao Hu   +6 more
doaj   +1 more source

The intracellular location of nitrogen metabolism enzymes in Pisum arvense L. roots

open access: yesActa Societatis Botanicorum Poloniae, 2014
The time course changes of nitrate assimilation enzymes and their distribution has been studied in Pisum arvense roots. The results indicate that nitrate reductase (EC 1.6.6.2) and glutamine synthetase (EC 6.3.1.2) are present in the soluble fraction ...
Grażyna Kłobus   +2 more
doaj   +1 more source

Cancer metabolism at a glance [PDF]

open access: yes, 2016
A defining hallmark of cancer is uncontrolled cell proliferation. This is initiated once cells have accumulated alterations in signaling pathways that control metabolism and proliferation, wherein the metabolic alterations provide the energetic and ...
Gottlieb, Eyal   +5 more
core   +2 more sources

Abnormalities in Glutamate Metabolism and Excitotoxicity in the Retinal Diseases

open access: yesScientifica, 2013
In the physiological condition, glutamate acts as an excitatory neurotransmitter in the retina. However, excessive glutamate can be toxic to retinal neurons by overstimulation of the glutamate receptors.
Makoto Ishikawa
doaj   +1 more source

Effect of chilling and acclimation on the activity of glutamine synthetase isoforms in maize seedlings [PDF]

open access: yesArchives of Biological Sciences, 2007
Effects of chilling and acclimation on the activity of cytosolic (GS1) and plastidic (GS2) isoforms of glutamine synthetase (E.C. 6.3.1.2) were studied in chilling-sensitive and acclimation-responsive maize inbred G50.
Simonović Ana D., Anderson M.D.
doaj   +1 more source

Direct molecular and spectroscopic evidence for increased ammonia removal capacity of skeletal muscle in acute liver failure

open access: yes, 2006
BACKGROUND/AIMS: It has been proposed that, in acute liver failure, skeletal muscle adapts to become the principle organ responsible for removal of blood-borne ammonia by increasing glutamine synthesis, a reaction that is catalyzed by the cytosolic ATP ...
Butterworth, Roger   +5 more
core   +1 more source

Leaf-Atmosphere NH3 Exchange in Barley Mutants with Reduced Activities of Glutamine Synthetase [PDF]

open access: yes, 1997
Mutants of barley (Hordeum vulgare L. cv Maris Mink) with 47 or 66% of the glutamine synthetase (GS) activity of the wild type were used for studies of NH3 exchange with the atmosphere.
Hausler, R.E.   +4 more
core   +3 more sources

L-arginine metabolism in mitochondria isolated from the liver of Antarctic fish Notothenia rossii and Notothenia neglecta

open access: yesBrazilian Archives of Biology and Technology, 2006
The arginase tissue distribution, the biochemical properties of the argininolytic system and the subcellular localization of the enzymes carbamoylphosphate synthetase, ornithinecarbamoyl transferase, glutamine synthetase and arginase in Antarctic fish, N.
Edson Rodrigues   +2 more
doaj   +1 more source

Glutamine Synthetase Promotes Radiation Resistance via Facilitating Nucleotide Metabolism and Subsequent DNA Damage Repair

open access: yesCell Reports, 2019
Summary: Radiation resistance is a critical problem in radiotherapy for cancer. Radiation kills tumor cells mainly through causing DNA damage. Thus, efficiency of DNA damage repair is one of the most important factors that limits radiotherapy efficacy ...
Shujun Fu   +15 more
doaj   +1 more source

In-vivo modification of Azotobacter-chroococcum glutamine-synthetase [PDF]

open access: yes, 1994
against glutamine synthetase of the unicellular cyanobacterium Synechocystis sp. strain PCC 6803 immunoreacted with glutamine synthetase from the N2-fixing heterotrophic bacterium Azotobacter chroococcum. In Western-blotting experiments this antibody
Aneque Guerrero, Antonio   +2 more
core  

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