Results 61 to 70 of about 216,468 (357)

Glutamine Synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

Nature Cell Biology, 2015
L-Glutamine (Gln) functions physiologically to balance the carbon and nitrogen requirements of tissues. It has been proposed that in cancer cells undergoing aerobic glycolysis, accelerated anabolism is sustained by Gln-derived carbons, which replenish ...
S. Tardito, A. Oudin, Shafiq U. Ahmed, F. Fack, O. Keunen, Liang Zheng, H. Miletic, P. Sakariassen, Adam Weinstock, Allon Wagner, Susan L. Lindsay, A. Hock, S. Barnett, E. Ruppin, S. H. Mørkve, M. Lund-Johansen, A. Chalmers, R. Bjerkvig, S. Niclou, E. Gottlieb   +19 more
semanticscholar   +1 more source

Abnormalities in Glutamate Metabolism and Excitotoxicity in the Retinal Diseases

Scientifica, 2013
In the physiological condition, glutamate acts as an excitatory neurotransmitter in the retina. However, excessive glutamate can be toxic to retinal neurons by overstimulation of the glutamate receptors.
Makoto Ishikawa
doaj   +1 more source

L-arginine metabolism in mitochondria isolated from the liver of Antarctic fish Notothenia rossii and Notothenia neglecta

Brazilian Archives of Biology and Technology, 2006
The arginase tissue distribution, the biochemical properties of the argininolytic system and the subcellular localization of the enzymes carbamoylphosphate synthetase, ornithinecarbamoyl transferase, glutamine synthetase and arginase in Antarctic fish, N.
Edson Rodrigues, Ana Cristina Miguez Teixeira Ribeiro, Metry Bacila   +2 more
doaj   +1 more source

Effect of chilling and acclimation on the activity of glutamine synthetase isoforms in maize seedlings [PDF]

Archives of Biological Sciences, 2007
Effects of chilling and acclimation on the activity of cytosolic (GS1) and plastidic (GS2) isoforms of glutamine synthetase (E.C. 6.3.1.2) were studied in chilling-sensitive and acclimation-responsive maize inbred G50.
Simonović Ana D., Anderson M.D.
doaj   +1 more source

Direct molecular and spectroscopic evidence for increased ammonia removal capacity of skeletal muscle in acute liver failure

, 2006
BACKGROUND/AIMS: It has been proposed that, in acute liver failure, skeletal muscle adapts to become the principle organ responsible for removal of blood-borne ammonia by increasing glutamine synthesis, a reaction that is catalyzed by the cytosolic ATP ...
Butterworth, Roger, Chatauret, Nicolas, Desjardins, Paul, Rao, Rama K. V., Rose, Christopher, Zwingmann, Claudia   +5 more
core   +1 more source

Delaying chloroplast turnover increases water-deficit stress tolerance through the enhancement of nitrogen assimilation in rice. [PDF]

, 2017
Abiotic stress-induced senescence in crops is a process particularly affecting the photosynthetic apparatus, decreasing photosynthetic activity and inducing chloroplast degradation.
Blumwald, Eduardo, Rubio Wilhelmi, Maria Del Mar, Sade, Nir, Umnajkitikorn, Kamolchanok, Wang, Songhu, Wright, Matthew   +5 more
core   +1 more source

Correlation of Exon 3 β-catenin Mutations with Glutamine Synthetase Staining Patterns in Hepatocellular Adenoma and Hepatocellular Carcinoma

Modern Pathology, 2016
The current clinical practice is based on the assumption of strong correlation between diffuse glutamine synthetase expression and β-catenin activation in hepatocellular adenoma and hepatocellular carcinoma. This high correlation is based on limited data
G. Hale, Xinxin Liu, Junjie Hu, Zhong Xu, L. Che, D. Solomon, C. Tsokos, N. Shafizadeh, Xin Chen, R. Gill, S. Kakar   +10 more
semanticscholar   +1 more source

Bacterial nitrate assimilation: gene distribution and regulation [PDF]

, 2011
In the context of the global nitrogen cycle, the importance of inorganic nitrate for the nutrition and growth of marine and freshwater autotrophic phytoplankton has long been recognized.
Andrew J. Gates, Assumpção, Caballero, Cabello, Chai, Chen, Conrado Moreno-Vivián, David J. Richardson, Flores, Forchhammer, Forchhammer, Gates, Gutierrez, Ishida, Kayumov, Koropatkin, Leigh, Li, Lin, Lledó, Llácer, M. Dolores Roldán, Moreno-Vivián, Nakano, Ogawa, Ohashi, Pawlowski, Paz-Yepes, Pino, Puerta-Fernández, Ramos, Richardson, Sanders, Shao, Shu, Shu, Stuart J. Ferguson, Swanson, Szeto, Toukdarian, Víctor M. Luque-Almagro, Weiss, Weiss, Wray, Wu   +44 more
core   +1 more source

Glutamine synthetase sequence evolution in the mycobacteria and their use as molecular markers for Actinobacteria speciation

BMC Evolutionary Biology, 2009
Background Although the gene encoding for glutamine synthetase (glnA) is essential in several organisms, multiple glnA copies have been identified in bacterial genomes such as those of the phylum Actinobacteria, notably the mycobacterial species ...
Wiid Ian JF, van Helden Paul D, Hayward Don   +2 more
doaj   +1 more source

In-vivo modification of Azotobacter-chroococcum glutamine-synthetase [PDF]

, 1994
against glutamine synthetase of the unicellular cyanobacterium Synechocystis sp. strain PCC 6803 immunoreacted with glutamine synthetase from the N2-fixing heterotrophic bacterium Azotobacter chroococcum. In Western-blotting experiments this antibody
Aneque Guerrero, Antonio, Cejudo Fernández, Francisco Javier, Muñoz Centeno, María de la Cruz   +2 more
core