Results 61 to 70 of about 91,004 (324)

Glutamine synthetase 2 is not essential for biosynthesis of compatible solutes in Halobacillus halophilus

Frontiers in Microbiology, 2014
Halobacillus halophilus, a moderately halophilic bacterium isolated from salt marshes, produces various compatible solutes to cope with osmotic stress. Glutamate and glutamine are dominant compatible solutes at mild salinities.
Anna eShiyan, Melanie eThompson, Saskia eKöcher, Michaela eTausendschön, Helena eSantos, Inga eHänelt, Volker eMüller   +6 more
doaj   +1 more source

Photorespiration: metabolic pathways and their role in stress protection [PDF]

, 2000
Photorespiration results from the oxygenase reaction catalysed by ribulose-1,5-bisphosphate carboxylase/ oxygenase. In this reaction glycollate-2-phosphate is produced and subsequently metabolized in the photorespiratory pathway to form the Calvin ...
Anderson L. E., Astrid Wingler, C. B. Osmond, C. H. Foyer, Downton W. J. S., G. Bock, Kacser H., Koch K. E., Nakamura Y., Noctor G., Noctor G., Nour J. M., Nour J. M., Osmond C. B., Peter J. Lea, Richard C. Leegood, Richardson K. E., Ruban A.V., Tolbert N. E., W. Paul Quick, Walker R. R., Wingler A.   +21 more
core   +2 more sources

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

Advanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan, Mengyao Zhang, Haiyue Guo, Yan Xu, Chenjie Xu, Fan Hu, Yinbing Pan, Xian Wang, Wentao Liu, Chun‐Yi Jiang   +9 more
wiley   +1 more source

Bacterial nitrate assimilation: gene distribution and regulation [PDF]

, 2011
In the context of the global nitrogen cycle, the importance of inorganic nitrate for the nutrition and growth of marine and freshwater autotrophic phytoplankton has long been recognized.
Andrew J. Gates, Assumpção, Caballero, Cabello, Chai, Chen, Conrado Moreno-Vivián, David J. Richardson, Flores, Forchhammer, Forchhammer, Gates, Gutierrez, Ishida, Kayumov, Koropatkin, Leigh, Li, Lin, Lledó, Llácer, M. Dolores Roldán, Moreno-Vivián, Nakano, Ogawa, Ohashi, Pawlowski, Paz-Yepes, Pino, Puerta-Fernández, Ramos, Richardson, Sanders, Shao, Shu, Shu, Stuart J. Ferguson, Swanson, Szeto, Toukdarian, Víctor M. Luque-Almagro, Weiss, Weiss, Wray, Wu   +44 more
core   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

Advanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi, Qingyu Li, Jian Li, Jian Bai, Ji Xi, Qi He, Jianglin Zhou, Xuejun Wang, Xiang Song, Xiaoju Li, Xiangpei Yue, Xiaochang Zhang, Zhen Sun, Jiangbo Li, Wen Yang, Yuke Cui, Wenjie Shu, Liang Guo, Shengqi Wang   +18 more
wiley   +1 more source

Nitrogen metabolism in a grapevine in vitro system

OENO One, 2002
Ammonium, nitrate, nitrite, protein and individual and total amino acid contents were determined in grapevine (cv Sauvignon) cultured in vitro. The enzyme activities of nitrate and nitrite reductases, glutamine synthetase, glutamate synthetase and ...
Nuria Llorens, Lluís Arola, Cinta Bladé, Albert Mas   +3 more
doaj   +1 more source

Glutamate biosynthesis in Bacillus azotofixans. 15N NMR and enzymatic studies [PDF]

, 1988
Pathways of ammonia assimilation into glutamic acid in Bacillus azotofixans, a recently characterized nitrogen-fixing species of Bacillus, were investigated through observation by NMR spectroscopy of in vivo incorporation of 15N into glutamine and ...
Kanamori, Keiko, Roberts, John D., Weiss, Richard L.   +2 more
core  

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Boosting Reversible Photocontrol of a Photoxenase by an Engineered Conformational Shift

Angewandte Chemie, EarlyView.
Photocontrol of enzymes with photoswitchable unnatural amino acids hitherto yielded only limited light‐regulation factors (LRFs). Here we boosted the LRF of an imidazole glycerol phosphate synthase variant from ∼15 to ∼100 in a semi‐rational design approach and unraveled the mechanistic fundamentals of this effect via biophysical and computational ...
Sabrina Mandl, Janet Sánchez, Miquel Estévez, Astrid Bruckmann, Caroline Hiefinger, Sílvia Osuna, Andrea Hupfeld   +6 more
wiley   +2 more sources

Biostimulant Effects of Seed-Applied Sedaxane Fungicide: Morphological and Physiological Changes in Maize Seedlings [PDF]

, 2017
Most crops are routinely protected against seed-born and soil-borne fungal pathogens through seed-applied fungicides. The recently released succinate dehydrogenase inhibitor (SDHI), sedaxane®, is a broad-spectrum fungicide, used particularly to control ...
DAL CORTIVO, Cristian, Conselvan, GIOVANNI BATTISTA, Carletti, Paolo, Barion, Giuseppe, Sella, Luca, Vamerali, Teofilo   +5 more
core   +5 more sources