Results 71 to 80 of about 78,410 (212)

Evaluation of the endogenous glucocorticoid hypothesis of denervation atrophy [PDF]

The effects are studied of the oral administration of RU38486, a potent selective glucocorticoid antagonist, on muscle weight, non-collagen protein content, and selected enzyme activities (choline acetyltransferase, glucose 6-phosphate dehydrogenase, and
Konagaya, Masaaki, Konagaya, Yoko, Max, Stephen R.   +2 more
core   +1 more source

Importance of the ammonia assimilation by Penicillium purpurogenum in amino derivative Monascus pigment, PP-V, production [PDF]

, 2013
A fungal strain, Penicillium purpurogenum IAM 15392, produced the azaphilone Monascus pigment homolog when cultured in a medium composed of soluble starch, ammonium nitrate, yeast extract, and citrate buffer, pH 5.0. One of the typical features of violet
Jun Kato, Jun Ogihara, Kasumi Koganei, Ryo Kojima, Sara Umemura, Takafumi Kasumi, Teppei Arai   +6 more
core   +1 more source

The herbicidal natural product phosphonothrixin is an inhibitor of the riboflavin biosynthetic enzyme L‐3,4‐dihydroxy‐2‐butanone‐4‐phosphate synthase

Pest Management Science, EarlyView.
An enzyme involved in vitamin B2 biosynthesis, 3,4‐dihydroxy‐2‐butanone‐4‐phosphate synthase (DHBPS), was identified as the target of the natural product phosphonothrixin, representing a novel mode of action for herbicides. Abstract BACKGROUND In our ongoing search for new and environmentally friendly chemical entities that can control weeds via new ...
Bernd Laber, Yoann Huet, Jörg Freigang, Hansjörg Dietrich, Wolfgang Schulte, David M. Barber   +5 more
wiley   +1 more source

Effect of the nitrogen source on glutamine and alanine biosynthesis in Neurospora crassa. An in vivo 15N nuclear magnetic resonance study [PDF]

, 1982
The influences of different nitrogen sources on the relative rates of biosynthesis of glutamine and alanine have been studied by 15N nuclear magnetic resonance spectroscopy of intact Neurospora crassa mycelia suspensions.
Kanamori, Keiko, Legerton, Timothy L., Roberts, John D., Weiss, Richard L.   +3 more
core  

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

Small Methods, EarlyView.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai, Jiawen Wang, Zihuan Lin, Danni Yu, Hui Yang, Jinsong Wei, Xiaoyu Li, Hao Hu, Chao Ni, Bing Zhao   +9 more
wiley   +1 more source

The response of diatom central carbon metabolism to nitrogen starvation is different from that of green algae and higher plants [PDF]

, 2011
The availability of nitrogen varies greatly in the ocean and limits primary productivity over large areas. Diatoms, a group of phytoplankton that are responsible for about 20% of global carbon fixation, respond rapidly to influxes of nitrate and are ...
Hockin, Nicola Louise, Kopriva, Stanislav, Malin, Gill, Mock, Thomas, Mulholland, Francis   +4 more
core   +1 more source

Dysregulation of glutaminase and glutamine synthetase in cancer

Cancer Letters, 2019
Besides fast glucose catabolism, many types of cancers are characterized by elevated glutamine consumption. Medical oncology pursuits to block specific pathways, mainly glycolysis and glutaminolysis, in tumor cells to arrest cancer development. This strategy frequently induces adaptive metabolic resistance that must be countered. Combination therapy is
Mates-Sánchez, José Manuel, Campos-Sandoval, José Ángel, De los Santos-Jiménez, Juan, Márquez-Gómez, Javier   +3 more
openaire   +5 more sources

Production Starch Using the Yeast (Cryptococcus neoformans HTM1 Strain) Isolated From Tea (Camellia sinensis)

Starch - Stärke, EarlyView.
Production of starch using the yeast isolated from tea (Camellia sinensis). Providing an alternative for the evaluation of fruit waste or fruits that are not of commercial importance. Starch production is independent of climate conditions. Newly isolated and characterized yeast from tea. ABSTRACT Starch is a staple food in human and animal nutrition as
Barbaros Dinçer, Emine Hacıosmanoğlu, Demet Kızıl, Şengül Alpay Karaoğlu   +3 more
wiley   +1 more source

Biostimulant Effects of Seed-Applied Sedaxane Fungicide: Morphological and Physiological Changes in Maize Seedlings [PDF]

, 2017
Most crops are routinely protected against seed-born and soil-borne fungal pathogens through seed-applied fungicides. The recently released succinate dehydrogenase inhibitor (SDHI), sedaxane®, is a broad-spectrum fungicide, used particularly to control ...
DAL CORTIVO, Cristian, Conselvan, GIOVANNI BATTISTA, Carletti, Paolo, Barion, Giuseppe, Sella, Luca, Vamerali, Teofilo   +5 more
core   +3 more sources

Plasma POSTN Derived From Bile Proteome Is a Promising Biomarker for Cholangiocarcinoma With Efficacy Comparable and Complementary to CA19.9

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background Cholangiocarcinoma presents a global health challenge due to its increasing incidence and poor prognosis, primarily resulting from delayed diagnosis. There is an urgent need for a reliable biomarker to enhance early detection. Materials and Methods Patients with cholangiocarcinoma were enrolled into three cohorts: a discovery set (n 
Lichieh Julie Chu, Chia‐Jung Tsai, Chun‐Chun Chien, Yung‐Chin Hsiao, Jau‐Song Yu, Jun‐Yi Tsai, Ta‐Sen Yeh   +6 more
wiley   +1 more source