Results 71 to 80 of about 216,468 (357)

Leaf-Atmosphere NH3 Exchange in Barley Mutants with Reduced Activities of Glutamine Synthetase [PDF]

, 1997
Mutants of barley (Hordeum vulgare L. cv Maris Mink) with 47 or 66% of the glutamine synthetase (GS) activity of the wild type were used for studies of NH3 exchange with the atmosphere.
Hausler, R.E., Lea, P.J., Leegood, R.C., Mattsson, M., Schjoerring, J.K.   +4 more
core   +3 more sources

Contributions of two cytosolic glutamine synthetase isozymes to ammonium assimilation in Arabidopsis roots

Journal of Experimental Botany, 2016
Highlight Temporal and spatial distributions of GLN1;2 and GLN1;3, the two low-affinity cytosolic glutamine synthetase isoforms, determine their contributions to ammonium assimilation in Arabidopsis roots.
N. Konishi, Keiki Ishiyama, M. Beier, Eri Inoue, K. Kanno, T. Yamaya, Hideki Takahashi, S. Kojima   +7 more
semanticscholar   +1 more source

Towards High‐Acuity Vision Restoration: Hybrid Retinal Prosthesis Composed of a High‐Density Multielectrode Array Integrated With Glutamatergic Cells

Advanced Functional Materials, EarlyView.
This work introduces a novel Hybrid Retinal Implant (HRI), composed of a high‐density electrode array integrated with glutamatergic neurons to overcome key limitations of current retinal prostheses. The significant reduction of activation threshold and of electrode cross‐talk yields in an improved spatial resolution.
Nairouz Farah, Amos Markus, Gal Shpun, Yoav Chemla, Erel Lasnoy, Tamar Azrad‐Leibovitch, Fikre Fentahon, Zeev Zalvesky, Yossi Mandel   +8 more
wiley   +1 more source

Advances in human glutamine-hydrolyzing synthetases and their therapeutic potential

Frontiers in Chemical Biology
Bifunctional enzymes, characterized by their dual active sites, enable efficient chemical conversion and substrate channeling using elegant coupling mechanisms to coordinate the two active sites. In humans, several bifunctional enzymes synthesize de novo
Wen Zhu, Alanya J. Nardone, Lucciano A. Pearce   +2 more
doaj   +1 more source

Glutamine Synthetase Promotes Radiation Resistance via Facilitating Nucleotide Metabolism and Subsequent DNA Damage Repair

Cell Reports, 2019
Summary: Radiation resistance is a critical problem in radiotherapy for cancer. Radiation kills tumor cells mainly through causing DNA damage. Thus, efficiency of DNA damage repair is one of the most important factors that limits radiotherapy efficacy ...
Shujun Fu, Zhi Li, Lanbo Xiao, Wenfeng Hu, Lu Zhang, Bowen Xie, Qin Zhou, Junju He, Yanfang Qiu, Ming Wen, Yanni Peng, Jie Gao, Rong Tan, Yuezhen Deng, Liang Weng, Lun-Quan Sun   +15 more
doaj   +1 more source

Ammonia assimilation in Bacillus polymyxa. 15N NMR and enzymatic studies [PDF]

, 1987
Pathways of ammonia assimilation into glutamic acid and alanine in Bacillus polymyxa were investigated by 15N NMR spectroscopy in combination with measurements of the specific activities of glutamate dehydrogenase, glutamine synthetase, glutamate ...
Kanamori, Keiko, Roberts, John D., Weiss, Richard L.   +2 more
core  

Limited capacity for ammonia removal by brain in chronic liver failure: potential role of nitric oxide

, 2005
Chronic liver failure leads to hyperammonemia and consequently increased brain ammonia concentrations, resulting in hepatic encephalopathy. When the liver fails to regulate ammonia concentrations, the brain, devoid of a urea cycle, relies solely on the ...
Felipo, Vicente, Rose, Christopher
core   +1 more source

The Regulation of Glutamine Transport and Glutamine Synthetase in Salmonella typhimurium [PDF]

Journal of General Microbiology, 1976
Transport of glutamine by the high-affinity transport system is regulated by the nitrogen status of the medium. With high concentrations of ammonia, transport is repressed; whereas with Casamino acids, transport is elevated, showing behaviour similar to glutamine synthetase.
P. D. Ayling, P. R. Betteridge
openaire   +2 more sources

UCP2 Upregulates ACSL3 to Enhance Lipid Droplet Release from Acinar Cells and Modulates the Sirt1/Smad3 Pathway to Promote Macrophage‐to‐Myofibroblast Transition in Chronic Pancreatitis

Advanced Science, EarlyView.
These findings suggest that UCP2 promotes LD formation and release in acinar cells by upregulating ACSL3 expression. This alteration in the local lipid metabolic environment indirectly drives the MMT process. Additionally, UCP2 may regulate the acetylation of Smad3 through Sirt1, enhancing its nuclear activity and activating the TGF‐β/ Smad3 signaling ...
Kunpeng Wang, Lilong Zhang, Beiying Deng, Wanrong Jiang, Tianrui Kuang, Chen Chen, Kailiang Zhao, Qiao Shi, Jun He, Weixing Wang   +9 more
wiley   +1 more source

Glutamine synthetase 2 is not essential for biosynthesis of compatible solutes in Halobacillus halophilus

Frontiers in Microbiology, 2014
Halobacillus halophilus, a moderately halophilic bacterium isolated from salt marshes, produces various compatible solutes to cope with osmotic stress. Glutamate and glutamine are dominant compatible solutes at mild salinities.
Anna eShiyan, Melanie eThompson, Saskia eKöcher, Michaela eTausendschön, Helena eSantos, Inga eHänelt, Volker eMüller   +6 more
doaj   +1 more source