Novel Glutamate–Putrescine Ligase Activity in Haloferax mediterranei: A New Function for glnA-2 Gene
Biomolecules, 2021 The genome of the halophilic archaea Haloferax mediterranei contains three ORFs that show homology with glutamine synthetase (GS) (glnA-1, glnA-2, and glnA-3).
Verónica Rodríguez-Herrero +5 more
doaj +1 more source
Effect of Ammonium-supplemented Seawater on Glutamine Synthetase and Glutamate Dehydrogenase Activities in Host Tissue and Zooxanthellae of Pocillopora damicornis and on Ammonium Uptake Rates of the Zooxanthellae [PDF]
, 1994 Host glutamine synthetase activity decreases in Pocillopora damicornis (Linnaeus) following exposure of the coral to seawater containing elevated ammonium (20 uM).
Fitt, W.K., Rees, TAV, Yellowlees, D.
core
Ammonia toxicity: from head to toe? [PDF]
, 2016 Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan +6 more
core +1 more source
Advanced Science, EarlyView.Glutamine deprivation triggers ACSL5 upregulation in tumor cells, sustaining their viability via dual metabolic rewiring programs. ACSL5 enhances glycolysis by relieving p53's inhibition of PGAM1 while also sustaining mitochondrial respiration and TCA cycle flux through promoting IDH2 dimerization.
Shuai Tian +11 more
wiley +1 more source
Minireview on Glutamine Synthetase Deficiency, an Ultra-Rare Inborn Error of Amino Acid Biosynthesis
Biology, 2016 Glutamine synthetase (GS) is a cytosolic enzyme that produces glutamine, the most abundant free amino acid in the human body. Glutamine is a major substrate for various metabolic pathways, and is thus an important factor for the functioning of many ...
Marta Spodenkiewicz +4 more
doaj +1 more source
Leaf-Atmosphere NH3 Exchange in Barley Mutants with Reduced Activities of Glutamine Synthetase [PDF]
, 1997 Mutants of barley (Hordeum vulgare L. cv Maris Mink) with 47 or 66% of the glutamine synthetase (GS) activity of the wild type were used for studies of NH3 exchange with the atmosphere.
Hausler, R.E. +4 more
core +3 more sources
Advanced Science, EarlyView.Four distinct satellite glial cell subtypes are identified in mouse dorsal root ganglia using single‐cell RNA sequencing and spatial validation. These subtypes show unique marker profiles and anatomical distributions. Human dorsal root ganglia display layered perisomatic organization with differential marker expression.
Ole Andreas Ahlgreen +13 more
wiley +1 more source
Genetics and Molecular Biology, 2005 This work was aimed at locating Eucalyptus ESTs corresponding to the GS enzyme (Glutamine Synthetase, EC = 6.3.1.2) and to the D1 protein, which are directly related to resistance to herbicides that promote oxidative stress.
Edivaldo Domingues Velini +9 more
doaj +1 more source
Macrophage Stimulated by Low Ambient Temperature Hasten Tumor Growth via Glutamine Production
Biomedicines, 2020 Ambient temperature can regulate the immune response and affect tumor growth. Although thermoneutral caging reduces tumor growth via immune activation, little attention has been paid to the tumorigenic effect of low temperature.
Eun-Ji Lee +8 more
doaj +1 more source
The Regulation of Glutamine Transport and Glutamine Synthetase in Salmonella typhimurium [PDF]
Journal of General Microbiology, 1976 Transport of glutamine by the high-affinity transport system is regulated by the nitrogen status of the medium. With high concentrations of ammonia, transport is repressed; whereas with Casamino acids, transport is elevated, showing behaviour similar to glutamine synthetase.
P R, Betteridge, P D, Ayling
openaire +2 more sources