Results 121 to 130 of about 135,439,936 (222)

Utility of Synechocystis sp. PCC glutaredoxin A as a platform to study high-resolution mutagenesis of proteins. [PDF]

, 2013
Glutaredoxin from the cyanobacterium Synechocystis sp. PCC 6803 is a small protein, containing only 88 amino acids, that participates in a large number of redox reactions, serving both as an electron donor for enzyme-catalyzed reductions and as a ...
David B Knaff, Roger Bryan Sutton, Knaff, David B., Roger B. Sutton, David B. Knaff, Sutton, Roger B.   +5 more
core   +1 more source

Iron-sulfur glutaredoxin 2 protects oligodendrocytes against damage induced by nitric oxide release from activated microglia

, 2017
Demyelinated brain lesions, a hallmark of autoimmune neuroinflammatory diseases like multiple sclerosis, result from oligodendroglial cell damage. Activated microglia are considered a major source of nitric oxide and subsequent peroxynitrite-mediated ...
Hildebrandt, T., Arne Holmgren, Lawrence Steinman, Klaudia Lepka, Natalia Rios, Thomas Hildebrandt, Volbracht, K., Berndt, C., Reiner Schneider, Lillig, C., Steinman, L., Ingwersen, J., Rafael Radi, Hartung, H., Orhan Aktas, Katrin Volbracht, Eckhard Bill, Schneider, R., Lepka, K., Holmgren, A., Bill, E., Prozorovski, T., Jack van Horssen, Carsten Berndt, Rios, N., van Horssen, J., Christopher Horst Lillig, Aktas, O., Timur Prozorovski, Jens Ingwersen, Hans-Peter Hartung, Radi, R., Prozorovski, T, Volbracht, K, Schneider, R, van, Horssen J, Rios, N, Hildebrandt, T, Bill, E, Lepka, K, Ingwersen, J, Lillig, CH   +41 more
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Preclinical Study of the Neuroprotective Effects of Pharmacological Agent-Modulators of HSP70 After Intrauterine Hypoxia

Journal of Integrative Neuroscience
Background:Chronic intrauterine hypoxia (IUH) is a cause not only of early postnatal mortality but also of delayed central nervous system (CNS) impairments in offspring, including increased risks of acute cerebrovascular disorders, epilepsy, and ...
Igor Belenichev, Olena Aliyeva, Nina Bukhtiyarova, Victor Ryzhenko, Sergiy Oliynyk, Suyeon Lee, Kyu-Ho Yi   +6 more
doaj   +1 more source

Enhancement of protein production in Aspergillus niger by engineering the antioxidant defense metabolism

Biotechnology for Biofuels and Bioproducts
Background Research on protein production holds significant importance in the advancement of food technology, agriculture, pharmaceuticals, and bioenergy.
Xin Chen, Baoxiang Pan, Leyi Yu, Bin Wang, Li Pan   +4 more
doaj   +1 more source

HSP₇₀ Modulators for the Correction of Cognitive, Mnemonic, and Behavioral Disorders After Prenatal Hypoxia

Biomedicines
Background/Objectives: Prenatal hypoxia (PH) is a leading cause of nervous system disorders in early childhood and subsequently leads to a decline in the cognitive and mnemonic functions of the central nervous system (such as memory impairment, reduced ...
Olena Aliyeva, Igor F. Belenichev, Ivan Bilai, Iryna Duiun, Lyudmyla Makyeyeva, Valentyn Oksenych, Oleksandr Kamyshnyi   +6 more
doaj   +1 more source

Positive Regulation of Interleukin-1β Bioactivity by Physiological ROS-Mediated Cysteine S-Glutathionylation

Cell Reports, 2017
Reactive oxygen species (ROS)-induced cysteine S-glutathionylation is an important posttranslational modification (PTM) that controls a wide range of intracellular protein activities.
Xue Zhang, Peng Liu, Christie Zhang, Direkrit Chiewchengchol, Fan Zhao, Hongbo Yu, Jingyu Li, Hiroto Kambara, Kate Y. Luo, Arvind Venkataraman, Ziling Zhou, Weidong Zhou, Haiyan Zhu, Li Zhao, Jiro Sakai, Yuanyuan Chen, Ye-Shih Ho, Besnik Bajrami, Bing Xu, Leslie E. Silberstein, Tao Cheng, Yuanfu Xu, Yuehai Ke, Hongbo R. Luo   +23 more
doaj   +1 more source

[[alternative]]Total synthesis and biological evaluation of glutathione disulfide analogue

, 2010
[[abstract]]Glutaredoxin為專門且有效地對protein-SSG進行去麩胺基硫反應（deglutathionylation）的催化蛋白質，此外，glutaredoxin也催化進行diglutathionylated HIV-1 protease的去麩胺基硫反應，使原本無活性的HIV-1 protease轉換成超活性狀態（superactive form）；諸多例子指出glutaredoxin幫助恢復了麩胺基硫化蛋白質（S-glutathionylated proteins ...
[[author]]田鎧豪, [[author]]Kai-Hau Tian, 田鎧豪, Kai-Hau Tian   +3 more
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Glutaredoxin-3 from Escherichia coli : Amino acid sequence, H-1 and N-15 NMR assignments, and structural analysis

, 1996
The primary and secondary structure of glutaredoxin-3 (Grx3), a glutathione-disulfide oxidoreductase from Escherichia coli, has been determined. The amino acid sequence of Grx3 consists of 82 residues and contains a redox-active motif, Cys-Pro-Tyr-Cys ...
Åslund, F, Berndt, Kurt D,, Nikkola, M, Otting, G, Holmgren, A, Nordstrand, K, Ponstingl, H, Bergman, T, Jornvall, H   +8 more
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Soybean Glutaredoxin Gene Responds to Aluminum Toxicity in Soil II [PDF]

, 2002
Oxidizing agents are a normal product of aerobic metabolism and may also be encountered from environmental sources. Aluminum is one proposed source of environmental oxidative stress in plants, and is a major component of soils and an inhibitor of plant ...
Thomas-Bostic, Kisha D.
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Glutaredoxin and glutathione regulate the activity of ATP7A AND ATP7B

, 2012
In this study it was shown that the antioxidant, glutathione, and the glutaredoxin-1 protein, have important new roles in regulating ATP7A and ATP7B - two key proteins which regulate intracellular copper levels in humans - by modulating how they bind ...
W Singleton (12145599)
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