Results 111 to 120 of about 135,439,936 (222)
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.Alcohol metabolism induces structural instability of iron‐sulfur clusters through ROS‐mediated oxidative damage and direct covalent modification of acetaldehyde. The iron‐sulfur cluster deficiency drives metabolic reprogramming by inactivating aconitase, accumulating succinate, and impairing tRNA thiolation, thereby promoting hepatic steatosis ...
Li Xu +6 more
wiley +1 more source
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.Phytofabricated metal oxide nanoparticles may activate the Nrf2–Keap1 axis through a dual‐stimulus mechanism, coupling nanoparticle‐derived ROS with phytochemical‐mediated Keap1 modification, steering mesenchymal stem cells toward osteogenic commitment — a mechanistic framework this review consolidates from current evidence.
Muhammad Irfan +3 more
wiley +1 more source
The Thioltransferase (Glutaredoxin) 1 Gene of Fission Yeast Is Regulated by Atf1 and Pap1
Molecules and Cells, 2003 We previously isolated a gene encoding thioltransferase (TTase1) from the fission yeast Schizosaccharomyces pombe. Using a TTase-lacZ fusion plasmid, carrying a 666 bp region upstream of the translation initiation point, we found that expression of TTase1 was enhanced by metal ions, diamide and NO-generating S-nitroso-N-acetylpenicillamine (SNAP).
Chang-Jin, Lim +4 more
openaire +2 more sources
Ergothioneine: Biosynthesis, Molecular Mechanisms, Physiological Function, and Role in Disease
MedComm, Volume 7, Issue 9, September 2026.Ergothioneine is a natural thione antioxidant with significant biomedical potential. By reducing oxidative stress, inflammation, mitochondrial dysfunction, and cellular injury, ergothioneine may support interventions for aging‐related disorders, neurodegeneration, metabolic diseases, and skin protection.
Guojuan Yi +6 more
wiley +1 more source
Double Alkynylation of Quinoline-5,8-diones and their In-silico and Antimicrobial Studies
Journal of Applied Sciences and Environmental Management, 2018 A double alkynylation of quinoline-5,8-dione to furnished bis-alkynylquinoline-5,8-dione in good yields and their in silico and antimicrobial studies is described.
MA Ezeokonkwo +5 more
doaj +1 more source
Dynamics of the glutathione/glutaredoxin system. [PDF]
, 2014 M. Sc. University of KwaZulu-Natal, Pietermaritzburg 2014.The glutathione/glutaredoxin system is made up of glutaredoxins, glutathione (GSH) and glutathione reductase (GLR).
Mashamaite, Lefentse Nelly.
core +1 more source
Redox Biology, 2019 Understanding the in vivo redox biology of cells is a complex albeit important biological problem. Studying redox processes within living cells without physical disruption or chemical modifications is essential in determining the native redox states of ...
Wilhad Hans Reuter +11 more
doaj +1 more source
Non-reciprocal regulation of the redox state of the glutathione-glutaredoxin and thioredoxin systems
, 2003 Our studies in yeast show that there is an essential requirement for either an active thioredoxin or an active glutathione (GSH)-glutaredoxin system for cell viability.
Eleanor W Trotter +3 more
core +1 more source
The Protective Role of Glutaredoxin‐1 in Endothelial Barrier Regulation and Atherosclerosis
The FASEB Journal, 2015 Vascular oxidative stress is widely invoked as an important pathogenic mechanism for atherosclerosis (AS). Protein S‐glutathionylation (P‐SSG), the prevalent post‐translational oxidative modification, is emerging as a critical redox signaling mechanism in cardiovascular diseases. However, its role in AS is not clear yet.
Jingyan Han, Richard Cohen, Reiko Matsui
openaire +1 more source
, 2006 International audienceThe existence of natural peroxiredoxin–glutaredoxin hybrid enzymes in several bacteria is in line with previous findings indicating that poplar peroxiredoxin II can use glutaredoxin as an electron donor.
Gans, Pierre +13 more
core +1 more source