Plasmodium falciparum glyoxalase II: Theorell-Chance product inhibition patterns, rate-limiting substrate binding via Arg(257)/Lys(260), and unmasking of acid-base catalysis [PDF]
, 2009 Glyoxalase II (GloII) is a ubiquitous thioester hydrolase catalyzing the last step of the glutathione-dependent conversion of 2-oxoaldehydes to 2-hydroxycarboxylic acids.
Elia A.C. +6 more
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Glutathione and mitochondria [PDF]
Frontiers in Pharmacology, 2014 Glutathione (GSH) is the main non-protein thiol in cells whose functions are dependent on the redox-active thiol of its cysteine moiety that serves as a cofactor for a number of antioxidant and detoxifying enzymes. While synthesized exclusively in the cytosol from its constituent amino acids, GSH is distributed in different compartments, including ...
Ribas, Vicent +2 more
openaire +4 more sources
A Mammalian Mediator Subunit that Shares Properties with Saccharomyces cerevisiae Mediator Subunit Cse2 [PDF]
, 2004 The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. We previously identified and partially purified a mammalian Mediator complex from rat liver nuclei (Brower ...
Banks, Charles A. S. +10 more
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Expression of a catalytically inactive mutant form of glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility. [PDF]
, 2015 The selenoenzyme Gpx4 is essential for early embryogenesis and cell viability for its unique function to prevent phospholipid oxidation. Recently, the cytosolic form of Gpx4 was identified as an upstream regulator of a novel form of non-apoptotic cell ...
Aichler, M +12 more
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Chloroplast Glutathione Reductase [PDF]
Plant Physiology, 1977 Glutathione reductase (EC 1.6.4.2) activity is present in spinach (Spinacia oleracea L.) chloroplasts. The pH dependence and substrate concentration for half-maximal rate are reported and a possible role in chloroplasts is proposed.
Michail Schaedle, James A. Bassham
openaire +3 more sources
Halotolerant Bacillus altitudinis WR10 improves salt tolerance in wheat via a multi-level mechanism
Frontiers in Plant Science, 2022 Soil salinity is an important abiotic stress factor that seriously affects the crop growth and yield. Use of plant-derived microorganisms is a promising strategy to alleviate salt stress.
Zonghao Yue +9 more
doaj +1 more source
Glutathione S-Transferases in Cancer
Antioxidants, 2021 In humans, the glutathione S-transferases (GST) protein family is composed of seven members that present remarkable structural similarity and some degree of overlapping functionalities.
R. Singh, Katie M. Reindl
semanticscholar +1 more source
Bistable equilibrium points of mercury body burden [PDF]
, 2007 In the last century mercury levels in the global environment have tripled as a result of increased pollution from industrial, occupational, medicinal and domestic uses \cite{BaMe03}. Glutathione is known to be the main agent responsible for the excretion
Boulos, Areen, Owhadi, Houman
core +2 more sources
Enhancement Glutathione Peroxidase Activity and α2-Macroglobulin Gene Expression of Macrobrachium Rosenbergii Fed with Aqueous Morinda Citrifolia Leaves Extract-Supplemented Diet [PDF]
, 2018 Morinda citrifolia, known commercially as noni is often used for enhance immunity, these plant rich of phenolic compound with antioxidant properties. In the present study, Macrobrachium rosenbergii were fed with diets containing of aqueous M.
Chang, C. C. (Chin) +2 more
core
Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]
, 2002 Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Baron, A. +5 more
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