Epigallocatechin-3-gallate enhances key enzymatic activities of hepatic thioredoxin and glutathione systems in selenium-optimal mice but activates hepatic Nrf2 responses in selenium-deficient mice [PDF]
Selenium participates in the antioxidant defense mainly through a class of selenoproteins, including thioredoxin reductase. Epigallocatechin-3-gallate (EGCG) is the most abundant and biologically active catechin in green tea.
Chen, Pingping+6 more
core +4 more sources
NOX-like ROS production by glutathione reductase. [PDF]
Summary: In organisms from bacteria to mammals, NADPH oxidase (NOX) catalyzes the production of beneficial reactive oxygen species (ROS) such as superoxide (O2−).
Diaz JM, Shi X.
europepmc +2 more sources
Evaluation of the salivary level of glutathione reductase, catalase and free thiol in patients with oral lichen planus. [PDF]
Objective Oral lichen planus (OLP) is a usual chronic inflammatory disease of the oral mucosa with malignant capacity, whose pathogenesis is not yet well known.
Rezazadeh F+5 more
europepmc +2 more sources
The assessment of glutathione, glutathione peroxidase, glutathione reductase, and oxidized glutathione in patients with periodontitis-A systematic review and meta-analysis. [PDF]
Objective The present systematic review explored the involvement of enzymatic and nonenzymatic antioxidants in periodontitis, drawing from established literature. Materials and Methods The research approach encompassed an extensive electronic search from
Mohideen K+5 more
europepmc +2 more sources
Dynamics of glutathione reductase activity in rat liver tissues during cryodestruction of the right atrium [PDF]
The metabolic processes of the human body are based on multiple redox reactions and oxidative stress occurs when homeostasis is imbalanced.
Pavlova Olga+4 more
doaj +1 more source
Long-term results of the enzyme glutation system activity in experimental ovarian cancer
The article presents the experimental results of the investigation the glutathione system activity (glutathione peroxidase and glutathione reductase) in rats simulated ovarian ascites tumor.
L. Yershova+4 more
doaj +1 more source
Quercetin-Induced Glutathione Depletion Sensitizes Colorectal Cancer Cells to Oxaliplatin
Quercetin is an antioxidant phytochemical which belongs to the natural flavonoids group. Recently, the compound has been reported to inhibit glutathione reductase responsible for replenishing reduced forms of glutathione and thus leads to glutathione ...
Jinkyung Lee+4 more
doaj +1 more source
Chloroplast Glutathione Reductase [PDF]
Glutathione reductase (EC 1.6.4.2) activity is present in spinach (Spinacia oleracea L.) chloroplasts. The pH dependence and substrate concentration for half-maximal rate are reported and a possible role in chloroplasts is proposed.
Michail Schaedle, James A. Bassham
openaire +3 more sources
It is known that the majority of pathological processes take place against the background of formation of active oxygen species and intensification of free radical oxidation of bio-substrates.
Boriskin Pavel+5 more
doaj +1 more source
Glutathione reductase inhibitors are very popular antimalarial and anticancer agents. In this study, in vitro inhibition effects of β-sitosterol, stigmasterol, diosgenin and jervine which containing steroidal structure were determined against glutathione
Tuba Aydin
doaj +1 more source