Results 31 to 40 of about 147,440 (362)

The flavin reductase ActVB from Streptomyces coelicolor: characterization of the electron transferase activity of the flavoprotein form [PDF]

FEBS Letters, Elsevier, 2005, 579, pp.2817-20, 2015
The flavin reductase ActVB is involved in the last step of actinorhodin biosynthesis in Streptomyces coelicolor. Although ActVB can be isolated with some FMN bound, this form was not involved in the flavin reductase activity. By studying the ferric reductase activity of ActVB, we show that its FMN-bound form exhibits a proper enzymatic activity of ...
arxiv   +1 more source

Cytosolic thioredoxin reductase 1 is required for correct disulfide formation in the ER [PDF]

, 2017
Folding of proteins entering the secretory pathway in mammalian cells frequently requires the insertion of disulfide bonds. Disulfide insertion can result in covalent linkages found in the native structure as well as those that are not, so‐called non ...
Elias SJ Arnér, Fourie AM, Greg J Poet, Marcel Lith, Marie Anne Pringle, Neil J Bulleid, Ojore BV Oka, Philip J Robinson, Zhenbo Cao   +8 more
core   +2 more sources

Effect of cadmium on antioxidative enzymes, glutathione content, and glutathionylation in tall fescue

Biologia Plantarum, 2014
The aim of this work was to assess the effect of different Cd2+concentrations on some antioxidant enzymes in Festuca arundinacea. Increased activities of ascorbate peroxidase, monodehydroascorbate reductase, dehydroascorbate reductase, glutathione S ...
D. Del Buono, T. Mimmo, R. Terzano, N. Tomasi, S. Cesco   +4 more
doaj   +1 more source

Remote ischemic conditioning improves rat brain antioxidant defense in a time-dependent mechanism

Acta Cirúrgica Brasileira, 2021
Purpose To clarify the best protocol for performing remote ischemic conditioning and to minimize the consequences of ischemia and reperfusion syndrome in brain, the present study aimed to evaluate different time protocols and the relation of the organs ...
Andrew Moraes Monteiro, Rodrigo Paracampo Couteiro, Dora Fonseca da Silva, Sérgio Cunha Trindade Júnior, Renata Cunha Silva, Luís Fernando Freitas de Sousa, Deivid Ramos dos Santos, Jofre Jacob da Silva Freitas, Marcus Vinícius Henriques Brito   +8 more
doaj   +1 more source

Dimethyl Fumarate Induces Glutathione Recycling by Upregulation of Glutathione Reductase [PDF]

Oxidative Medicine and Cellular Longevity, 2017
Neuronal degeneration in multiple sclerosis has been linked to oxidative stress. Dimethyl fumarate (DMF) is an effective oral therapeutic option shown to reduce disease activity and progression in patients with relapsing‐remitting multiple sclerosis. DMF activates the transcription factor nuclear factor erythroid 2‐related factor 2 (NRF2) leading to ...
Christina Hoffmann, Michael Dietrich, Ann-Kathrin Herrmann, Teresa Schacht, Philipp Albrecht, Axel Methner   +5 more
openaire   +4 more sources

CydDC-mediated reductant export in Escherichia coli controls the transcriptional wiring of energy metabolism and combats nitrosative stress [PDF]

, 2016
The glutathione/cysteine exporter CydDC maintains redox balance in Escherichia coli. A cydD mutant strain was used to probe the influence of CydDC upon reduced thiol export, gene expression, metabolic perturbations, intracellular pH homeostasis, and ...
Cook, Gregory M, Holyoake, Louise V, Howard, Mark J., Hunt, Stuart, Poole, Robert K, Rowe, Michelle L., Sanguinetti, Guido, Shepherd, Mark   +7 more
core   +3 more sources

Effect of ochratoxin A and buthionine sulfoximine on proteome and ascorbate-glutathione cycle enzymes in Arabidopsis thaliana

Biologia Plantarum, 2015
In this study, proteome and activities of glutathione (GSH)-related enzymes were investigated in detached leaves of Arabidopsis thaliana treated with ochratoxin A (OTA) alone or supplemented with buthionine sulfoximine (BSO, a specific inhibitor of the ...
J. R. Hao, Y. Wang, W. W. Zhao, W. T. Xu, Y. B. Luo, Z. J. Yang, W. H. Wu, Z. H. Liang, K. L. Huang   +8 more
doaj   +1 more source

The binding of the retro-analogue of glutathione disulfide to glutathione reductase. [PDF]

Journal of Biological Chemistry, 1990
The retro-analogue of glutathione disulfide was bound to the GSSG binding site of crystalline glutathione reductase. The binding mode revealed why the analogue is a very poor substrate in enzyme catalysis. The observed binding mode difference between natural substrate and retro-analogue is explained.
Georg E. Schulz, W Janes
openaire   +2 more sources

Adaptive response to oxidative stress in the filamentous fungus Aspergillus niger B1-D [PDF]

, 2008
In the present study, we used a recombinant filamentous fungus strain, Aspergillus niger B1-D, as a model system, and investigated the antioxidant defences in this organism.
Harvey, L.M., Li, Qiang, Mcneil, Brian
core   +1 more source

The Effect of an Aqueous Extract of Teucrium polium on Glutathione Homeostasis In Vitro: A Possible Mechanism of Its Hepatoprotectant Action

Advances in Pharmacological Sciences, 2010
Background. Teucrium polium is used in Arab traditional medicine to treat liver diseases. Glutathione is an important intracellular antioxidant, and intrahepatic glutathione levels are depleted in liver diseases. Hypothesis and Aim.
Stella Shtukmaster, Predrag Ljubuncic, Arieh Bomzon   +2 more
doaj   +1 more source