Results 131 to 140 of about 18,229,039 (247)

Versatile Co‐Engineering of Immunogenic Cell Death‐Primed Dead Tumor Cell Bodies With Tumor‐Activated MnO2 for cGAS‐STING‐Potentiated Personalized Immunotherapy

open access: yesAdvanced Science, EarlyView.
DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu   +6 more
wiley   +1 more source

The activity of the antioxidant protection enzymatic system of boars with a decrease in their reproductive capacity under oxidative stress

open access: yesTheoretical and Applied Veterinary Medicine, 2020
It was found that enzymatic system activity of the antioxidant protection of the breeding boars organism with a decrease in their reproductive ability under oxidative stress was significantly decreased, which was noted by a decrease in the antioxidant ...
V. I. Koshevoy, S. V. Naumenko
doaj  

Targeting brain cells with glutathione-modulated nanoliposomes: in vitro and in vivo study

open access: yes, 2015
Heba F Salem,1 Sayed M Ahmed,2 Ashraf E Hassaballah,3 Mahmoud M Omar1,4 1Department of Pharmaceutics and Industrial Pharmacy, Beni-suef University, 2Department of Industrial Pharmacy, Assiut University, 3Department of Clinical Pathology, Faculty of ...
Salem HF   +3 more
core  

State of glutathione system in the serum of rats in experimental osteoarthritis and administration of chondroitin sulphate

open access: yes, 2017
It was established that in osteoarthritis induced by administering of sodium monoiodacetate in the blood serum of rats glutathione system enzyme activities reduced – glutathione peroxidase, glutathione, oxidized glutathione and the ratio of redox ...
Y. Kovelska   +3 more
core   +1 more source

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao   +5 more
wiley   +1 more source

Liquid Gallium Nanozyme Coatings Enable Sustained Nitric Oxide Generation With Antioxidant and Anti‐Inflammatory Functions

open access: yesAdvanced Science, EarlyView.
Liquid gallium (Ga) acts as a catalytic center for nitric oxide (NO) generation within a tannic acid–zirconium metal–phenolic network coating. Stabilized Ga nanoparticles catalyze S‐nitrosothiol decomposition through surface electron transfer, enabling controlled NO production, enhancing endothelial biocompatibility, and providing antioxidant and anti ...
Franco Centurion   +10 more
wiley   +1 more source

Effect of Cold Treatment on Glutathione Synthesis in Maize Seedlings

open access: yes, 1993
Institut für Pflanzenwissenschaften (IPS)2Paper erschienen in: Proceedings of the First European Workshop on Glutathione: Regulation, Cellular Defences & Clinical Aspects, p.
Brunold, Christian, Kocsy, Gabor
core  

TAB2 Causes Neuronal Damage by Aggravating Microglia‐Mediated Neuroinflammation in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
In microglia, STAT3 upregulates TAB2, which promotes NF‐κB activation through its NZF domain‐mediated recognition of K63‐linked ubiquitin chains, leading to inflammatory cytokine release and subsequent neuronal injury. Lumacaftor suppresses TAB2 expression and directly binds the TAB2‐NZF domain to interrupt K63 ubiquitin recognition, thereby blocking ...
Yanhao Zhao   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy