Results 11 to 20 of about 428,300 (333)
Glutathione Transferase P1: Potential Therapeutic Target in Ovarian Cancer [PDF]
Medicina, 2022 Chemotherapy resistance of ovarian cancer, regarded as the most lethal malignant gynecological disease, can be explained by several mechanisms, including increased activity of efflux transporters leading to decreased intracellular drug accumulation ...
Petar Simic +10 more
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The Multifaceted Role of Glutathione S-Transferases in Health and Disease
Biomolecules, 2023 In humans, the cytosolic glutathione S-transferase (GST) family of proteins is encoded by 16 genes presented in seven different classes. GSTs exhibit remarkable structural similarity with some overlapping functionalities. As a primary function, GSTs play
Aslam M. A. Mazari +5 more
semanticscholar +1 more source
Glutathione-binding site of a bombyx mori theta-class glutathione transferase. [PDF]
PLoS ONE, 2014 The glutathione transferase (GST) superfamily plays key roles in the detoxification of various xenobiotics. Here, we report the isolation and characterization of a silkworm protein belonging to a previously reported theta-class GST family.
M D Tofazzal Hossain +2 more
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Clinical study of copeptin in serum patiants of heart diseases
Tikrit Journal of Pure Science, 2023 The study included the estimation copeptin level in serum of healthy and patients with heart diseases . The Results indicated that the level of copeptin in serum was (36.2±1.1 pg/mL) in control group for both sex, with the age range between ) 37 -
Thikra Ali Allwsh, Noori Mohammed Aziz
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Frontiers in Medicine, 2022 Psoriasis vulgaris is a chronic inflammatory skin disease characterized by well-demarcated scaly plaques. Oxidative stress plays a crucial role in the psoriasis pathogenesis and is associated with the disease severity.
Elena Campione +16 more
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Plant Glutathione Transferases [PDF]
, 2005 Soluble plant glutathione transferases (GSTs) consist of seven distinct classes, six of which have been functionally characterized. The phi and tau class GSTs are specific to plants and the most numerous and abundant of these enzymes. Both have classic conjugating activities toward a diverse range of xenobiotics, including pesticides, where they are ...
Robert, Edwards, David P, Dixon
openaire +2 more sources
S-Denitrosylation: A Crosstalk between Glutathione and Redoxin Systems
Antioxidants, 2022 S-nitrosylation of proteins occurs as a consequence of the derivatization of cysteine thiols with nitric oxide (NO) and is often associated with diseases and protein malfunction.
Surupa Chakraborty +8 more
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Glutathione transferase and mammary tumors
Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки, 2019 The analysis of publications from the last 5 years is presented in this review. These articles describe the relationship of glutathione transferase (GST) with mammary tumors.
O. M. Fedets, I. M. Kurlyak
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A structure-based mechanism of cisplatin resistance mediated by glutathione transferase P1-1
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance The resurgence of platinum-based chemotherapy in the last few years has renewed interest in the field, including clinical studies of cisplatin in combination with resistance modulators.
A. De Luca +12 more
semanticscholar +1 more source
The expression of GST isoenzymes and p53 in non-small cell lung cancer.
Folia Histochemica et Cytobiologica, 2010 This study investigated the immunohistochemical staining characteristics of glutathione-S-transferase alpha, pi, mu, theta and p53 in non-small cell lung carcinoma and normal lung tissue from 50 patients.
MĂźzeyyen Ozhavzali +6 more
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