Results 51 to 60 of about 27,788 (240)

von Willebrand factor and early diabetic retinopathy: no evidence for a relationship in patients with Type 1 (insulin-dependent) diabetes mellitus and normal urinary albumin excretion [PDF]

, 1992
High plasma levels of von Willebrand factor, an indicator of endothelial cell dysfunction, have been reported in both diabetic retinopathy and nephropathy.
Baarsma, G.S. (Seerp), Donker, A.J.M. (Ab J.), Nauta, J.J.P. (Jos), Ottolander, G.J. (Gerard) den, Polak, B.C.P. (Bettine), Stehouwer, C.D. (Coen), Zellenrath, P. (P.)   +6 more
core   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

Protein glycation – biomarkers of metabolic dysfunction and early-stage decline in health in the era of precision medicine

Redox Biology, 2021
Protein glycation provides a biomarker in widespread clinical use, glycated hemoglobin HbA1c (A1C). It is a biomarker for diagnosis of diabetes and prediabetes and of medium-term glycemic control in patients with established diabetes.
Naila Rabbani, Paul J. Thornalley
doaj   +1 more source

Myocardial inflammation is associated with impaired mitochondrial oxidative capacity in ischaemic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1246-1255, April 2025.
Abstract Aims Myocardial inflammation and impaired mitochondrial oxidative capacity are hallmarks of heart failure (HF) pathophysiology. The extent of myocardial inflammation in patients suffering from ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and its association with mitochondrial energy metabolism are unknown.
Julius Borger, Elric Zweck, Constanze Moos, Patrick Horn, Fabian Voß, Heinz‐Peter Schultheiss, Jacob Eifer Møller, Udo Boeken, Hug Aubin, Artur Lichtenberg, Malte Kelm, Michael Roden, Amin Polzin, Ralf Westenfeld, Julia Szendroedi, Daniel Scheiber   +15 more
wiley   +1 more source

Synergistic Effect of Hesperidin, Acarbose, and Exercise Combination on Neuroinflammation and Neurochemical Alterations in Diabetic Encephalopathy Rat Model

Food Chemistry International, EarlyView.
Diabetic encephalopathy (DME) impairs neurobehavior, neurochemicals, oxidative stress, and inflammation. This study evaluated the effects of hesperidin (HSP), exercise (EX), and acarbose (ACA) alone or combined on diabetic rats. Treatments reduced AChE, BChE, ACE, arginase, ATPDase, 5′‐nucleotidase, ADA, LDH, TBARS, and ROS, while increasing IL‐10, SOD,
Idowu Sunday Oyeleye, Olajide Raymond Ojo, Taiwo Olawale Adeleke, Adeyinka Sunday Ajeigbe, Mercy Gladys Tenywa, Oboh Ganiyu   +5 more
wiley   +1 more source

Advanced glycation endproducts in the pathogenesis of chronic kidney disease [PDF]

, 2018
Advanced glycation endproducts (AGEs) are stable post-translational modifications of proteins formed by the spontaneous reaction with glucose and related metabolites. Important AGEs quantitatively are methylglyoxal (MG)-derived hydroimidazolone MG-H1, Nε-
Rabbani, Naila, Thornalley, Paul J.
core   +1 more source

The Association Between Stress‐Induced Hyperglycemia Ratio and Increased Urinary Albumin Excretion in Patients With Hypertension: A Population‐Based Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The stress hyperglycemia ratio (SHR), a novel marker reflecting relative hyperglycemia, has been increasingly recognized for its prognostic value in cardiovascular and metabolic diseases. However, its association with early renal damage in hypertensive patients remains underexplored.
Kai‐Jun Zhang, Yun Lan, Wen‐Feng Zeng, Rong‐Ting Zhang, Zhi‐Yi Ma, Xin Zou   +5 more
wiley   +1 more source

Correlation of serum lipids and glycosylated hemoglobin with cognitive function in peritoneal dialysis patients

Linchuang shenzangbing zazhi
Objective To explore the relevant factors affecting cognitive function in continuous ambulatory peritoneal dialysis (CAPD) patients and evaluate the relationship between blood lipids and glycosylated hemoglobin and cognitive function in CAPD patients ...
Mai Zhang, Hua-ying Pei
doaj   +1 more source

Diabetes mellitus and necrotizing fasciitis – a deadly combination; case report [PDF]

, 2020
Necrotizing fasciitis is a rapidly destructive affliction of soft tissues, with a mortality rate that may reach 73% of the cases. It is characterized by a progressive inflammation and extended necrosis of the subcutaneous tissue and the fascia ...
Andronache, Liliana Florina, Bica, Cristina, Gherghiceanu, Florentina, Mazilu, Laura, Moroianu, Lavinia Alexandra, Paunica, Ioana, Sandu, Camelia, Suceveanu, Andra Iulia, Toma, Alexandra   +8 more
core   +3 more sources