Results 31 to 40 of about 27,788 (240)

Methylglyoxal induces platelet hyperaggregation and reduces thrombus stability by activating PKC and inhibiting PI3K/Akt pathway [PDF]

, 2013
Diabetes is characterized by a dysregulation of glucose homeostasis and platelets from patients with diabetes are known to be hyper-reactive and contribute to the accelerated development of vascular diseases.
Elgheznawy, Amro, Fleming, Ingrid, Hadas, Karin, Mann, Alexander, Randriamboavonjy, Voahanginirina   +4 more
core   +6 more sources

Definition of the upper reference limit of glycated albumin in blood donors from Italy [PDF]

, 2017
Glycated Albumin (GA) has been proposed as a short-term indicator of glycemic homeostasis. The aim of this study is to describe the distribution of GA in a large sample of blood donors from Italy to evaluate whether demographic features, namely age and ...
Agnello, Luisa, Bellia, Chiara, Bivona, Giulia, Ciaccio, Marcello, Cosma, Chiara, Plebani, Mario, Sasso, Bruna Lo, Zaninotto, Martina   +7 more
core   +1 more source

Association between serum albumin and glycated hemoglobin in Asian Indian subjects

Indian Journal of Endocrinology and Metabolism, 2015
Background: Protein glycation plays a signifi cant role in diabetic complications. Glycated hemoglobin (HbA1c) is a known predictor of diabetes and its complications.
Shalbha Tiwari, Manish Bothale, Imtiaz Hasan, Mahesh J Kulkarni, Mehmood G Sayyad, Rita Basu, Ananda Basu, Ambika Gopalakrishnan Unnikrishnan   +7 more
doaj   +1 more source

Follow-up of blood-pressure lowering and glucose control in type 2 diabetes. [PDF]

, 2014
BACKGROUND In the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) factorial trial, the combination of perindopril and indapamide reduced mortality among patients with type 2 diabetes, but ...
Arima, H, Billot, L, Chalmers, J, Colagiuri, S, Cooper, M, Davoren, Peter, Glasziou, P, Grobbee, D, Group, ADVANCE-ON Collaboration, Harnett, P, Harrap, S, Heller, S, Hirakawa, Y, Joshi, R, Li, Q, Lisheng, L, MacMahon, S, Mancia, G, Marre, M, Matthews, D, Mogensen, C, Monaghan, H, Neal, B, Patel, A, Perkovic, V, Poulter, N, Rodgers, A, Williams, B, Woodward, M, Zoungas, S   +29 more
core   +4 more sources

Alternative biomarkers for assessing glycemic control in diabetes: fructosamine, glycated albumin, and 1,5-anhydroglucitol [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2015
The growing attention to alternative glycemic biomarkers including fructosamine, glycated albumin (GA), 1,5-anhydroglucitol (1,5-AG), is attributable to the limitations of the glycated hemoglobin (HbA1c) assay. It is important to recognize the conditions
Ji-Eun Lee
doaj   +1 more source

Papaverine increases human serum albumin glycation [PDF]

Journal of Biological Physics, 2014
Glycation is a non-enzymatic reaction that is initiated by the primary addition of sugars to amino groups of proteins. In the early phase of glycation, the synthesis of intermediates leads to formation of Amadori compounds. In the last phase, advanced glycation end products (AGE) are irreversibly formed following a complex cascade of reactions.
openaire   +2 more sources

From Cure to Complexity: Post-SVR Liver and Metabolic Trajectories in Diabetic Patients. [PDF]

Liver Int
ABSTRACT Background and Aims The long‐term impact of HCV cure on hepatic and metabolic outcomes in patients with type 2 diabetes (T2D) remains insufficiently defined. This study evaluated T2D‐related vascular complications, liver disease progression and overall survival over 9 years of follow‐up, also exploring genetic variability contribution ...
Asero C, Franzè MS, Maltese T, La Spada A, Lombardo D, Grisanti C, Russo G, Giandalia A, Pitrone C, Filomia R, Caccamo G, Saitta C, Licata A, Pollicino T, Cacciola I.   +14 more
europepmc   +2 more sources

Oxidative stress, protein glycation and nutrition – interactions relevant to health and disease throughout the lifecycle [PDF]

, 2014
Protein glycation has been studied for over a century now and plays an important role in disease pathogenesis throughout the lifecycle. Strongly related to diabetic complications, glycation of Hb has become the gold standard method for diabetes diagnosis
American Diabetes, Antonis Vlassopoulos, Bhagwat, El-Salem, Emilie Combet, Hao, Hodge, Khaw, Koenig, Maillard, Malickova, Michael E. J. Lean, Monnier, Nicholl, Rothwell, Schmidt, Sell, Vlassara   +17 more
core   +3 more sources

Influence of biological variations and sample handling on measured microalbuminuria in diabetic patients [PDF]

, 1992
Five immunochemical assays for determining low concentrations of albumin were investigated. These were a radioimmunoassay (RIA); turbidimetric immunoassays (TIA) both according to end-point measuring principle on a Cobas Fara and Hitachi 717 analysers ...
Cowell, Elving, Erman, Ghiggeri, Giampietro, Hayashi, Jarrett, Mogensen, Mogensen, Nathan, Osberg, Passing, Rowe, Silver, Tomaselli, Townsend, Ukita, Viberti, Wiegmann, Yudkin   +19 more
core   +3 more sources

DJ-1 as a deglycating enzyme: A unique function to explain a multifaceted protein? [PDF]

, 2017
The recently reported deglycating activity of DJ-1 reconciles several features previously described for the protein. The deglycating activity reported for DJ-1 may explain its different subcellular localizations, indeed the protein has been found in the ...
Bisaglia, Marco, DE LAZZARI, Federica
core   +2 more sources